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Gene: Gabra5 (gamma-aminobutyric acid type A receptor alpha 5 subunit) Rattus norvegicus
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Symbol: Gabra5
Name: gamma-aminobutyric acid type A receptor alpha 5 subunit
Description: Exhibits GABA receptor binding activity; GABA-A receptor activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to benzodiazepine receptor activity and extracellular ligand-gated ion channel activity. Involved in brain development and chemical synaptic transmission. Localizes to several cellular components, including the GABA-ergic synapse; integral component of synaptic membrane; and neuronal cell body membrane. Human ortholog(s) of this gene implicated in bipolar disorder and mental depression. Orthologous to human GABRA5 (gamma-aminobutyric acid type A receptor alpha5 subunit); INTERACTS WITH (+)-pilocarpine; 6-propyl-2-thiouracil; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GABA(A) receptor subunit alpha-5; GABA-A receptor alpha-5 subunit; gamma-aminobutyric acid (GABA) A receptor, alpha 5; gamma-aminobutyric acid (GABA-A) receptor subunit alpha 5; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5; gamma-aminobutyric acid A receptor, alpha 5; gamma-aminobutyric acid receptor subunit alpha-5
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01112,833,941 - 112,947,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01113,844,235 - 113,955,760 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41108,843,086 - 108,955,130 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11108,921,428 - 109,033,473 (-)NCBI
Celera1102,441,576 - 102,547,389 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gabra5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61859
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.