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Gene: Folh1 (folate hydrolase 1) Rattus norvegicus
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Symbol: Folh1
Name: folate hydrolase 1
Description: Predicted to have Ac-Asp-Glu binding activity; peptidase activity; and tetrahydrofolyl-poly(glutamate) polymer binding activity. Involved in positive regulation of apoptotic process and proteolysis. Predicted to localize to the cell surface and integral component of plasma membrane. Orthologous to several human genes including FOLH1 (folate hydrolase 1); PARTICIPATES IN folate cycle metabolic pathway; folate mediated one-carbon metabolic pathway; folate metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: FGCP; folate hydrolase; folylpoly-gamma-glutamate carboxypeptidase; GCPII; glutamate carboxypeptidase 2; glutamate carboxypeptidase II; membrane glutamate carboxypeptidase; mGCP; N-acetylated alpha-linked acidic dipeptidase; N-acetylated-alpha-linked acidic dipeptidase I; Naalad; NAALADase I; prostate-specific membrane antigen homolog; pteroylpoly-gamma-glutamate carboxypeptidase
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01150,323,768 - 150,395,415 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01156,631,301 - 156,702,948 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41142,936,379 - 143,010,358 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11143,014,784 - 143,088,764 (-)NCBI
Celera1138,771,206 - 138,844,472 (-)NCBICelera
Cytogenetic Map1q32NCBI
RH 3.4 Map11111.7RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Folh1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70963
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.