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Gene: Smg1 (SMG1, nonsense mediated mRNA decay associated PI3K related kinase) Rattus norvegicus
Symbol: Smg1
Name: SMG1, nonsense mediated mRNA decay associated PI3K related kinase
RGD ID: 1563508
Description: Predicted to have protein serine/threonine kinase activity and telomeric DNA binding activity. Predicted to be involved in several processes, including nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; phosphorylation; and regulation of telomere maintenance. Predicted to localize to cytoplasm and nucleoplasm. Orthologous to human SMG1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil; amphetamine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC499250; LOC691397; LOW QUALITY PROTEIN: serine/threonine-protein kinase SMG1; RGD1563508; serine/threonine-protein kinase SMG1; similar to PI-3-kinase-related kinase SMG-1; similar to PI-3-kinase-related kinase SMG-1 isoform 2; smg-1 homolog, phosphatidylinositol 3-kinase-related kinase; smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans); SMG1 phosphatidylinositol 3-kinase-related kinase
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01187,781,577 - 187,882,833 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,784,270 - 187,883,157 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01194,735,685 - 194,836,308 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,347,187 - 176,442,991 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1170,228,494 - 170,329,833 (-)NCBICelera
Cytogenetic Map1q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Smg1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563508
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.