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Gene: Med25 (mediator complex subunit 25) Rattus norvegicus
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Symbol: Med25
Name: mediator complex subunit 25
Description: Predicted to have retinoid X receptor binding activity. Predicted to be involved in several processes, including positive regulation of chromatin binding activity; positive regulation of mediator complex assembly; and regulation of transcription by RNA polymerase II. Predicted to localize to the mediator complex and nuclear transcription factor complex. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B2. Orthologous to human MED25 (mediator complex subunit 25); PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH bisphenol A; vinclozolin; 17alpha-ethynylestradiol (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC292889; mediator of RNA polymerase II transcription subunit 25; mediator of RNA polymerase II transcription, subunit 25 homolog; mediator of RNA polymerase II transcription, subunit 25 homolog (yeast) ; RGD1305137; similar to RIKEN cDNA 2610034E13
Orthologs:
Homo sapiens (human) : MED25 (mediator complex subunit 25)  HGNC  Alliance
Mus musculus (house mouse) : Med25 (mediator complex subunit 25)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Med25 (mediator complex subunit 25)
Pan paniscus (bonobo/pygmy chimpanzee) : MED25 (mediator complex subunit 25)
Canis lupus familiaris (dog) : MED25 (mediator complex subunit 25)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Med25 (mediator complex subunit 25)
Sus scrofa (pig) : MED25 (mediator complex subunit 25)
Chlorocebus sabaeus (green monkey) : MED25 (mediator complex subunit 25)
Heterocephalus glaber (naked mole-rat) : Med25 (mediator complex subunit 25)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01100,872,240 - 100,887,864 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,874,976 - 100,887,853 (-)Ensembl
Rnor_5.01101,936,861 - 101,952,758 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,351,526 - 95,364,403 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1195,429,640 - 95,442,595 (-)NCBI
Celera189,624,421 - 89,637,298 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Med25
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305137
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.