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Gene: Ap2a1 (adaptor related protein complex 2 subunit alpha 1) Rattus norvegicus
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Symbol: Ap2a1
Name: adaptor related protein complex 2 subunit alpha 1
Description: Exhibits protein C-terminus binding activity. Involved in positive regulation of neuron projection development and positive regulation of receptor-mediated endocytosis. Localizes to several cellular components, including the apical plasma membrane; basolateral plasma membrane; and clathrin-coated vesicle. Orthologous to human AP2A1 (adaptor related protein complex 2 subunit alpha 1); PARTICIPATES IN Arf family mediated signaling pathway; clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH 2,6-dinitrotoluene; bis(2-ethylhexyl) phthalate; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adaptor protein complex AP-2, alpha 1 subunit; adaptor-related protein complex 2, alpha 1 subunit; alpha-adaptin A; AP-2 complex subunit alpha-1; LOC308578
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01100,896,582 - 100,926,443 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,896,947 - 100,926,335 (-)Ensembl
Rnor_5.01101,961,206 - 101,990,841 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,373,135 - 95,403,376 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1195,451,977 - 95,481,455 (-)NCBI
Celera189,646,459 - 89,675,632 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ap2a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306254
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.