Enables protein C-terminus binding activity. Involved in positive regulation of neuron projection development and positive regulation of receptor-mediated endocytosis. Located in apical plasma membrane; basolateral plasma membrane; and clathrin-coated vesicle. Part of protein-containing complex. Orthologous to human AP2A1 (adaptor related protein complex 2 subunit alpha 1); PARTICIPATES IN Arf family mediated signaling pathway; clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bis(2-ethylhexyl) phthalate.
[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of AP2A1 mRNA, [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of AP2A1 gene
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of AP2A1 mRNA
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AP2A1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of AP2A1 mRNA
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AP2A1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of AP2A1 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of AP2A1 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of AP2A1 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of AP2A1 mRNA
[Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of AP2A1 mRNA, [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of AP2A1 mRNA
[Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of AP2A1 mRNA, [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of AP2A1 mRNA