Ap2a1 (adaptor related protein complex 2 subunit alpha 1)

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Gene: Ap2a1 (adaptor related protein complex 2 subunit alpha 1) Rattus norvegicus

Analyze

Symbol:

Ap2a1

Name:

adaptor related protein complex 2 subunit alpha 1

RGD ID:

1306254

Description:

Exhibits protein C-terminus binding activity. Involved in positive regulation of neuron projection development and positive regulation of receptor-mediated endocytosis. Localizes to several cellular components, including apical plasma membrane; basolateral plasma membrane; and clathrin-coated vesicle. Orthologous to human AP2A1 (adaptor related protein complex 2 subunit alpha 1); PARTICIPATES IN Arf family mediated signaling pathway; clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH 2,6-dinitrotoluene; bis(2-ethylhexyl) phthalate; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

adaptor protein complex AP-2, alpha 1 subunit; adaptor-related protein complex 2, alpha 1 subunit; alpha-adaptin A; AP-2 complex subunit alpha-1; LOC308578

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	95,384,303 - 95,414,249 (-)	NCBI
Rnor_6.0 Ensembl	1	100,896,947 - 100,926,335 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	1	100,896,582 - 100,926,443 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	101,961,206 - 101,990,841 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,373,135 - 95,403,376 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	95,451,977 - 95,481,455 (-)	NCBI
Celera	1	89,646,459 - 89,675,632 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

aflatoxin B2 (ISO)

alpha-pinene (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP)

bisphenol F (ISO)

bortezomib (ISO)

C60 fullerene (EXP)

chlordecone (ISO)

cobalt atom (EXP)

dexamethasone (ISO)

dibutyl phthalate (EXP)

dioxygen (ISO)

ethanol (ISO)

folic acid (ISO)

indometacin (ISO)

iron atom (EXP)

iron(0) (EXP)

lead diacetate (ISO)

lead(0) (ISO)

lead(2+) (ISO)

lipopolysaccharide (ISO)

methapyrilene (ISO)

N-ethyl-N-nitrosourea (ISO)

nickel atom (EXP)

ozone (ISO)

paracetamol (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

tamoxifen (ISO)

tetrahydropalmatine (ISO)

trichloroethene (EXP)

triptonide (ISO)

tungsten (EXP,ISO)

zinc protoporphyrin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

clathrin-dependent endocytosis (IBA,ISO)

intracellular protein transport (IEA)

negative regulation of hyaluronan biosynthetic process (ISO)

positive regulation of neuron projection development (IMP)

positive regulation of receptor-mediated endocytosis (IMP)

receptor-mediated endocytosis (IBA)

Cellular Component

AP-2 adaptor complex (IBA,ISO)

apical plasma membrane (IDA)

basolateral plasma membrane (IDA)

clathrin-coated vesicle (IDA)

filopodium tip (ISO)

membrane coat (ISO)

protein-containing complex (IDA)

Molecular Function

cargo adaptor activity (IBA)

clathrin adaptor activity (IBA)

low-density lipoprotein particle receptor binding (ISO)

protein binding (IPI,ISO)

protein C-terminus binding (IPI)

protein kinase binding (ISO)

protein-containing complex binding (IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

Arf family mediated signaling pathway (ISO)

clathrin-dependent synaptic vesicle endocytosis (ISO)

endocytosis pathway (IEA)

Huntington's disease pathway (IEA)

References

References - curated


1.	Chen H, etal., J Biol Chem. 1999 Feb 5;274(6):3257-60.
2.	Duncker SV, etal., J Neurosci. 2013 May 29;33(22):9508-19. doi: 10.1523/JNEUROSCI.5689-12.2013.
3.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	GOA data from the GO Consortium
5.	Kamiguchi H and Yoshihara F, J Neurosci. 2001 Dec 1;21(23):9194-203.
6.	Legendre-Guillemin V, etal., J Biol Chem 2002 May 31;277(22):19897-904.
7.	MGD data from the GO Consortium
8.	Nashida T, etal., Arch Histol Cytol. 2003 Mar;66(1):45-52.
9.	Pipeline to import KEGG annotations from KEGG into RGD
10.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11.	RGD automated data pipeline
12.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13.	RGD automated import pipeline for gene-chemical interactions
14.	RGD comprehensive gene curation
15.	Rotem-Yehudar R, etal., J Biol Chem. 2001 Aug 31;276(35):33054-60. Epub 2001 Jun 21.
16.	Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
17.	Wasiak S, etal., J Cell Biol 2002 Sep 2;158(5):855-62. Epub 2002 Sep 03.

Additional References at PubMed

PMID:9259551	PMID:9694653	PMID:11382783	PMID:11879655	PMID:12234931	PMID:16903783	PMID:19946888	PMID:21307259	PMID:21499258	PMID:21700703	PMID:22262466	PMID:23509262
PMID:23676497	PMID:24251095	PMID:24305805	PMID:26005850	PMID:26771574	PMID:31505169

Genomics

Comparative Map Data

Ap2a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	95,384,303 - 95,414,249 (-)	NCBI
Rnor_6.0 Ensembl	1	100,896,947 - 100,926,335 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	1	100,896,582 - 100,926,443 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	101,961,206 - 101,990,841 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,373,135 - 95,403,376 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	95,451,977 - 95,481,455 (-)	NCBI
Celera	1	89,646,459 - 89,675,632 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

AP2A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	19	49,766,968 - 49,807,113 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p13 Ensembl	19	49,767,001 - 49,807,114 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	19	49,767,001 - 49,807,114 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	19	50,270,258 - 50,310,371 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	54,961,992 - 55,002,181 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	19	54,961,991 - 55,002,181	NCBI
Celera	19	47,139,637 - 47,179,822 (+)	NCBI
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	46,646,519 - 46,686,682 (+)	NCBI		HuRef
CHM1_1	19	50,271,982 - 50,312,188 (+)	NCBI		CHM1_1

Ap2a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,549,797 - 44,578,914 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	7	44,549,797 - 44,578,920 (-)	Ensembl
GRCm38	7	44,900,373 - 44,929,490 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	44,900,373 - 44,929,496 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,155,743 - 52,184,860 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	7	44,768,425 - 44,797,510 (-)	NCBI			mm8
Celera	7	40,350,575 - 40,379,662 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI

Ap2a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,117,636 - 1,143,409 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,117,380 - 1,143,403 (-)	NCBI	ChiLan1.0	ChiLan1.0

AP2A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	55,696,819 - 55,736,570 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,694,070 - 55,736,570 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	46,779,196 - 46,820,055 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

AP2A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,752,326 - 106,784,803 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	106,751,800 - 106,784,663 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	106,335,247 - 106,367,722 (-)	NCBI
ROS_Cfam_1.0	1	107,273,281 - 107,305,783 (-)	NCBI
UMICH_Zoey_3.1	1	106,945,343 - 106,977,824 (-)	NCBI
UNSW_CanFamBas_1.0	1	106,587,348 - 106,619,846 (-)	NCBI
UU_Cfam_GSD_1.0	1	107,427,815 - 107,460,313 (-)	NCBI

Ap2a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,944,676 - 21,978,793 (+)	NCBI
SpeTri2.0	NW_004936664	3,562,800 - 3,596,983 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AP2A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	54,786,511 - 54,823,904 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	54,786,537 - 54,823,906 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	50,515,632 - 50,553,005 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AP2A1
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	42,933,303 - 42,968,963 (+)	NCBI
ChlSab1.1 Ensembl	6	42,953,693 - 42,969,427 (+)	Ensembl

Ap2a1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624832	4,513,977 - 4,540,080 (-)	NCBI

Position Markers

Ap2a1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	100,896,605 - 100,896,781	NCBI	Rnor6.0
Rnor_5.0	1	101,961,224 - 101,961,399	UniSTS	Rnor5.0
RGSC_v3.4	1	95,373,155 - 95,373,937	UniSTS	RGSC3.4
Celera	1	89,646,048 - 89,646,293	UniSTS
Cytogenetic Map	1	q22	UniSTS

AW530045

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	100,896,358 - 100,896,561	NCBI	Rnor6.0
Rnor_5.0	1	101,960,977 - 101,961,180	UniSTS	Rnor5.0
RGSC_v3.4	1	95,372,908 - 95,373,111	UniSTS	RGSC3.4
Celera	1	89,645,801 - 89,646,004	UniSTS
RH 3.4 Map	1	908.59	UniSTS
Cytogenetic Map	1	q22	UniSTS

MARC_23449-23450:1027106382:1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	100,902,674 - 100,903,158	NCBI	Rnor6.0
Rnor_5.0	1	101,967,292 - 101,967,776	UniSTS	Rnor5.0
RGSC_v3.4	1	95,379,830 - 95,380,314	UniSTS	RGSC3.4
Celera	1	89,652,186 - 89,652,670	UniSTS
Cytogenetic Map	1	q22	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5655769	122614963	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	23406428	108057505	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	25951907	130917265	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34993530	173445086	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	35377692	217372257	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43579208	126240667	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43579208	126240667	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43579208	126240667	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43579208	126240667	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43579208	126240667	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	cortical volumetric bone mineral density (CMO:0001730)	1	43579208	126240667	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43579208	126240667	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	49147799	156446783	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49578577	169852184	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49578693	217054291	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	57761301	104391981	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	58209327	103209327	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	58354072	161711996	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	64588516	125875986	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	66113339	122614963	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	79134941	113593716	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	79689548	124689548	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	82788437	239853971	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	83502376	128502376	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	83656882	126240667	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	85779320	130779320	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	85917265	130917265	Rat
4889494	Scort2	Serum corticosterone level QTL 2	4.2		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	86776571	131776571	Rat
2300324	Fetw1	Fetal weight QTL 1	12.1	0.005	fetal growth trait (VT:0004201)	fetal body weight (CMO:0002080)	1	88634585	106002500	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	90804143	161321256	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)	1	91093646	136093646	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	94201400	184846632	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	94201400	197187904	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	94225372	130917265	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94364073	153076991	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	95304961	156446783	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	99983293	127203999	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	99983293	188289386	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	99983293	198656062	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	99983293	216213510	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	99983293	216325819	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	100131562	236763528	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	100354344	145354344	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	77
Count of miRNA genes:	69
Interacting mature miRNAs:	75
Transcripts:	ENSRNOT00000020304
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	36	49	33	19	33	3	6	74	35	41	11	3
Low		7	8	8		8	5	5					5
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094894	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000020304 ⟹ ENSRNOP00000020304

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	100,896,947 - 100,926,335 (-)	Ensembl

RefSeq Acc Id:

NM_001107511 ⟹ NP_001100981

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	95,384,668 - 95,414,057 (-)	NCBI
Rnor_6.0	1	100,896,947 - 100,926,335 (-)	NCBI
Rnor_5.0	1	101,961,206 - 101,990,841 (-)	NCBI
RGSC_v3.4	1	95,373,135 - 95,403,376 (-)	RGD
Celera	1	89,646,459 - 89,675,632 (-)	NCBI

Sequence:

show sequence

ATGCCGGCTGTATCCAAAGGCGATGGCATGCGTGGGCTTGCCGTGTTCATCTCCGACATCCGGA
ACTGCAAGAGCAAAGAGGCTGAGATCAAGAGGATCAACAAGGAACTGGCCAACATCCGCTCCAA
GTTCAAAGGGGACAAGGCCTTGGATGGCTACAGTAAAAAGAAGTATGTGTGTAAGCTGCTCTTC
ATCTTCCTGCTTGGCCATGACATTGACTTTGGACACATGGAGGCTGTGAACCTGCTAAGCTCCA
ACAAGTACACAGAGAAGCAGATAGGGTACCTGTTCATCTCAGTCCTGGTGAACTCGAACTCAGA
GCTGATCCGGCTCATTAACAACGCTATCAAGAACGACCTGGCCAGTCGCAACCCCACCTTCATG
TGCCTGGCTTTGCACTGTATTGCCAACGTGGGCAGCCGTGAGATGGGCGAGGCCTTTGCTGCCG
ACATTCCCCGAATCCTGGTGGCCGGAGACAGCATGGATAGTGTGAAGCAGAGTGCAGCCCTATG
CCTACTGCGTCTCTACAAGGCCTCCCCCGACTTGGTGCCCATGGGCGAGTGGACGGCCCGGGTG
GTGCATTTGCTCAATGATCAGCACATGGGAGTGGTCACAGCCGCTGTCAGTCTCATCACCTGCC
TGTGCAAGAAGAATCCAGATGACTTCAAGACCTGTGTCTCCCTGGCTGTGTCTCGCCTAAGCCG
GATTGTCTCCTCAGCCTCCACTGACCTCCAGGACTACACTTACTACTTCGTTCCTGCACCCTGG
CTCTCTGTGAAGTTACTGCGGTTGCTACAGTGTTACCCACCGCCAGAGGATGCGGCTGTGAAAG
GGCGGTTAGTGGAGTGTCTTGAGACTGTGCTCAACAAGGCCCAGGAGCCTCCCAAGTCCAAGAA
GGTGCAGCACTCCAATGCCAAGAACGCCATCCTGTTTGAGACTATTAGCCTCATCATCCACTAT
GACAGTGAGCCCAACCTCCTGGTCCGTGCCTGCAACCAGCTGGGCCAGTTCCTGCAGCACCGAG
AGACGAACCTGCGCTACCTGGCTCTGGAGAGCATGTGCACCCTGGCCAGCTCCGAGTTCTCCCA
CGAGGCTGTCAAGACCCACATTGATACTGTTATTAATGCCCTCAAGACTGAGCGGGACGTGAGT
GTGAGGCAGCGGGCAGCTGATCTGCTGTATGCCATGTGTGACCGGAGCAATGCCAAGCAGATTG
TATCAGAGATGCTGCGGTACCTAGAGACGGCTGACTATGCCATCCGAGAGGAGATTGTGCTGAA
GGTGGCCATCTTGGCTGAGAAGTATGCAGTGGACTACAGCTGGTATGTGGACACCATCCTCAAC
CTCATCCGCATTGCAGGCGACTATGTGAGCGAGGAGGTGTGGTACCGAGTGCTGCAGATCGTCA
CCAACCGTGATGATGTCCAGGGTTATGCTGCCAAGACAGTGTTTGAGGCCCTCCAGGCCCCAGC
CTGTCATGAGAACATGGTGAAGGTCGGTGGCTACATCCTTGGGGAGTTTGGGAACTTGATTGCT
GGGGACCCACGCTCCAGCCCACCTGTGCAGTTCTCACTGCTGCACTCCAAGTTCCACCTGTGCA
GTGTGGCCACTCGTGCCTTGCTGCTGTCCACCTACATCAAGTTCATCAACCTCTTCCCTGAGAC
CAAGGCCACCATCCAAGGTGTTCTTCGTGCCGGCTCCCAGCTGCGCAATGCTGACGTGGAGCTA
CAGCAGCGGGCAGTGGAGTACCTCACCCTCAGCTCTGTAGCTAGCACCGATGTTTTGGCTACTG
TGCTAGAAGAAATGCCCCCATTTCCTGAGCGGGAGTCATCCATTTTGGCTAAGCTGAAGCGTAA
GAAGGGCCCTGGGGCAGCCAGTGCCCTGGATGACAGCCGCAGGGACACCAGCAGCAATGACATC
AATGGGGGTGTGGAGCCCACCCCCAGCAATGTGTCAACCCCCTCACCCTCCGCGGACCTCTTGG
GGCTGCGGGCAGCCCCTCCCCCTGCTGCACCCCCAGCTCCTGTAGGCGGGAACCTCCTGGTGGA
TGTTTTCTCTGACGGCCCCACTGCACAGCCCAGCCTGGGTCCCACCCCTGAGGAGGCCTTCCTC
AGCGAGCTGGAGCCCCCTGCCCCTGAGAGCCCCATGACTTTGTTGGCTGACCCAGCTCCAGCTG
CTGACCCAGGTCCTGAGGACATAGGTCCTCCCATTCCAGAAGCAGATGAACTGCTGAATAAGTT
CGTGTGTAAGAATAGTGGGGTCTTGTTTGAGAACCAGCTGCTGCAGATCGGAGTCAAGTCTGAG
TTCCGGCAGAACCTGGGCCGCATGTATCTCTTCTATGGCAACAAGACTTCTGTGCAGTTCCAGA
GCTTCTTGCCCACCGTGGTCCACCCTGGGGACCTCCAGACTCATCTGGCGGTGCAGACCAAGCG
TGTAGCTGCACAAGTGGACGGTGGCGCACAGGTGCAGCAAGTACTCAACATTGAGTGTCTGCGA
GACTTCTTGACGCCACCACTGCTGTCGGTGCGCTTCCGGTACGGTGGCACCGCCCAGTCCCTCA
CTCTGAAGCTCCCAGTGACCATCAACAAATTCTTCCAGCCCACAGAGATGGCCGCCCAGGACTT
TTTCCAGCGCTGGAAGCAGCTGAGCCTCCCCCTGCAGGAGGCACAGAAAATCTTCAAAGCCAAC
CACCCCATGGATGCTGAAGTCACAAAGGCCAAGCTTCTGGGGTTTGGCTCTGCTCTTCTGGACA
ATGTGGATCCCAACCCTGAGAACTTTGTGGGTGCTGGAATCATCCAGACGAAAGCCCTGCAGGT
GGGGTGTCTGCTTCGACTGGAGCCCAATGCCCAGGCCCAAATGTACCGCCTAACCCTGCGCACC
AGCAAAGAGCCTGTGTCCCGTCACTTATGTGAGCTGCTGGCCCAGCAGTTCTGA

hide sequence

RefSeq Acc Id:

XM_006229064 ⟹ XP_006229126

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	95,384,303 - 95,414,249 (-)	NCBI
Rnor_6.0	1	100,896,582 - 100,926,443 (-)	NCBI
Rnor_5.0	1	101,961,206 - 101,990,841 (-)	NCBI

Sequence:

show sequence

GCCCTCCCCCGGCCGGCTCCTCGGCGCCGTCTGGGGTCCTTTCCGCCCGGTGCTGCCAGCCAGC
CCCGCGCCCGTTCGGCCAGGCCTGGAGCCGAGCCCTTCGCCATCATGCCGGCTGTATCCAAAGG
CGATGGCATGCGTGGGCTTGCCGTGTTCATCTCCGACATCCGGAACTGCAAGAGCAAAGAGGCT
GAGATCAAGAGGATCAACAAGGAACTGGCCAACATCCGCTCCAAGTTCAAAGGGGACAAGGCCT
TGGATGGCTACAGTAAAAAGAAGTATGTGTGTAAGCTGCTCTTCATCTTCCTGCTTGGCCATGA
CATTGACTTTGGACACATGGAGGCTGTGAACCTGCTAAGCTCCAACAAGTACACAGAGAAGCAG
ATAGGGTACCTGTTCATCTCAGTCCTGGTGAACTCGAACTCAGAGCTGATCCGGCTCATTAACA
ACGCTATCAAGAACGACCTGGCCAGTCGCAACCCCACCTTCATGTGCCTGGCTTTGCACTGTAT
TGCCAACGTGGGCAGCCGTGAGATGGGCGAGGCCTTTGCTGCCGACATTCCCCGAATCCTGGTG
GCCGGAGACAGCATGGATAGTGTGAAGCAGAGTGCAGCCCTATGCCTACTGCGTCTCTACAAGG
CCTCCCCCGACTTGGTGCCCATGGGCGAGTGGACGGCCCGGGTGGTGCATTTGCTCAATGATCA
GCACATGGGAGTGGTCACAGCCGCTGTCAGTCTCATCACCTGCCTGTGCAAGAAGAATCCAGAT
GACTTCAAGACCTGTGTCTCCCTGGCTGTGTCTCGCCTAAGCCGGATTGTCTCCTCAGCCTCCA
CTGACCTCCAGGACTACACTTACTACTTCGTTCCTGCACCCTGGCTCTCTGTGAAGTTACTGCG
GTTGCTACAGTGTTACCCACCGCCAGAGGATGCGGCTGTGAAAGGGCGGTTAGTGGAGTGTCTT
GAGACTGTGCTCAACAAGGCCCAGGAGCCTCCCAAGTCCAAGAAGGTGCAGCACTCCAATGCCA
AGAACGCCATCCTGTTTGAGACTATTAGCCTCATCATCCACTATGACAGTGAGCCCAACCTCCT
GGTCCGTGCCTGCAACCAGCTGGGCCAGTTCCTGCAGCACCGAGAGACGAACCTGCGCTACCTG
GCTCTGGAGAGCATGTGCACCCTGGCCAGCTCCGAGTTCTCCCACGAGGCTGTCAAGACCCACA
TTGATACTGTTATTAATGCCCTCAAGACTGAGCGGGACGTGAGTGTGAGGCAGCGGGCAGCTGA
TCTGCTGTATGCCATGTGTGACCGGAGCAATGCCAAGCAGATTGTATCAGAGATGCTGCGGTAC
CTAGAGACGGCTGACTATGCCATCCGAGAGGAGATTGTGCTGAAGGTGGCCATCTTGGCTGAGA
AGTATGCAGTGGACTACAGCTGGTATGTGGACACCATCCTCAACCTCATCCGCATTGCAGGCGA
CTATGTGAGCGAGGAGGTGTGGTACCGAGTGCTGCAGATCGTCACCAACCGTGATGATGTCCAG
GGTTATGCTGCCAAGACAGTGTTTGAGGCCCTCCAGGCCCCAGCCTGTCATGAGAACATGGTGA
AGGTCGGTGGCTACATCCTTGGGGAGTTTGGGAACTTGATTGCTGGGGACCCACGCTCCAGCCC
ACCTGTGCAGTTCTCACTGCTGCACTCCAAGTTCCACCTGTGCAGTGTGGCCACTCGTGCCTTG
CTGCTGTCCACCTACATCAAGTTCATCAACCTCTTCCCTGAGACCAAGGCCACCATCCAAGGTG
TTCTTCGTGCCGGCTCCCAGCTGCGCAATGCTGACGTGGAGCTACAGCAGCGGGCAGTGGAGTA
CCTCACCCTCAGCTCTGTAGCTAGCACCGATGTTTTGGCTACTGTGCTAGAAGAAATGCCCCCA
TTTCCTGAGCGGGAGTCATCCATTTTGGCTAAGCTGAAGCGTAAGAAGGGCCCTGGGGCAGCCA
GTGCCCTGGATGACAGCCGCAGGGACACCAGCAGCAATGACATCAATGGGGGTGTGGAGCCCAC
CCCCAGCAATGTGTCAACCCCCTCACCCTCCGCGGACCTCTTGGGGCTGCGGGCAGCCCCTCCC
CCTGCTGCACCCCCAGCTCCTGTAGGCGGGAACCTCCTGGTGGATGTTTTCTCTGACGGCCCCA
CTGCACAGCCCAGCCTGGGTCCCACCCCTGAGGAGGCCTTCCTCAGCGAGCTGGAGCCCCCTGC
CCCTGAGAGCCCCATGACTTTGTTGGCTGACCCAGCTCCAGCTGCTGACCCAGGTCCTGAGGAC
ATAGGTCCTCCCATTCCAGAAGCAGATGAACTGCTGAATAAGTTCGTGTGTAAGAATAGTGGGG
TCTTGTTTGAGAACCAGCTGCTGCAGATCGGAGTCAAGTCTGAGTTCCGGCAGAACCTGGGCCG
CATGTATCTCTTCTATGGCAACAAGACTTCTGTGCAGTTCCAGAGCTTCTTGCCCACCGTGGTC
CACCCTGGGGACCTCCAGACTCAGCTGGCGGTGCAGACCAAGCGTGTAGCTGCACAAGTGGACG
GTGGCGCACAGGTGCAGCAAGTACTCAACATTGAGTGTCTGCGAGACTTCTTGACGCCACCACT
GCTGTCGGTGCGCTTCCGGTACGGTGGCACCGCCCAGTCCCTCACTCTGAAGCTCCCAGTGACC
ATCAACAAATTCTTCCAGCCCACAGAGATGGCCGCCCAGGACTTTTTCCAGCGCTGGAAGCAGC
TGAGCCTCCCCCTGCAGGAGGCACAGAAAATCTTCAAAGCCAACCACCCCATGGATGCTGAAGT
CACAAAGGCCAAGCTTCTGGGGTTTGGCTCTGCTCTTCTGGACAATGTGGATCCCAACCCTGAG
AACTTTGTGGGTGCTGGAATCATCCAGACGAAAGCCCTGCAGGTGGGGTGTCTGCTTCGACTGG
AGCCCAATGCCCAGGCCCAAATGTACCGCCTAACCCTGCGCACCAGCAAAGAGCCTGTGTCCCG
TCACTTATGTGAGCTGCTGGCCCAGCAGTTCTGAGCCCTGGACTTGCCCTGGGATATGGCCGGT
GCCAGGCAGCCCTGAGATGGAGGCAGCTGTGGTGGAGGGGGACAGCGAGGGGACCTCCAGTGGT
GACAGCAAAGACCCCAGGGATGGGGGCATGCCTGGCGCGTCCTCTGGCCTTTGTATTTTATTTT
TGTTCATCTGCTGCTGTTTACATTCTGGGGGGTCAAGGGAAGCACCCTCCCTTCCTTGTCCCCC
GAAGCACAGAGGGGAGGGGGGCCGGGGAAGTAGGTACCTCCTCCCCTCCCCCTCCCTCCTTTTC
ACCCTCCTCCCTCCCTCCCTCTCCCCGTCCAGGGGCCGTGTATTATTGTGAGCGAATAAACAGA
GAGACGCTAATATTA

hide sequence

RefSeq Acc Id:

XM_006229065 ⟹ XP_006229127

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	95,384,303 - 95,414,249 (-)	NCBI
Rnor_6.0	1	100,896,582 - 100,926,443 (-)	NCBI
Rnor_5.0	1	101,961,206 - 101,990,841 (-)	NCBI

Sequence:

show sequence

GCCCTCCCCCGGCCGGCTCCTCGGCGCCGTCTGGGGTCCTTTCCGCCCGGTGCTGCCAGCCAGC
CCCGCGCCCGTTCGGCCAGGCCTGGAGCCGAGCCCTTCGCCATCATGCCGGCTGTATCCAAAGG
CGATGGCATGCGTGGGCTTGCCGTGTTCATCTCCGACATCCGGAACTGCAAGAGCAAAGAGGCT
GAGATCAAGAGGATCAACAAGGAACTGGCCAACATCCGCTCCAAGTTCAAAGGGGACAAGGCCT
TGGATGGCTACAGTAAAAAGAAGTATGTGTGTAAGCTGCTCTTCATCTTCCTGCTTGGCCATGA
CATTGACTTTGGACACATGGAGGCTGTGAACCTGCTAAGCTCCAACAAGTACACAGAGAAGCAG
ATAGGGTACCTGTTCATCTCAGTCCTGGTGAACTCGAACTCAGAGCTGATCCGGCTCATTAACA
ACGCTATCAAGAACGACCTGGCCAGTCGCAACCCCACCTTCATGTGCCTGGCTTTGCACTGTAT
TGCCAACGTGGGCAGCCGTGAGATGGGCGAGGCCTTTGCTGCCGACATTCCCCGAATCCTGGTG
GCCGGAGACAGCATGGATAGTGTGAAGCAGAGTGCAGCCCTATGCCTACTGCGTCTCTACAAGG
CCTCCCCCGACTTGGTGCCCATGGGCGAGTGGACGGCCCGGGTGGTGCATTTGCTCAATGATCA
GCACATGGGAGTGGTCACAGCCGCTGTCAGTCTCATCACCTGCCTGTGCAAGAAGAATCCAGAT
GACTTCAAGACCTGTGTCTCCCTGGCTGTGTCTCGCCTAAGCCGGATTGTCTCCTCAGCCTCCA
CTGACCTCCAGGACTACACTTACTACTTCGTTCCTGCACCCTGGCTCTCTGTGAAGTTACTGCG
GTTGCTACAGTGTTACCCACCGCCAGAGGATGCGGCTGTGAAAGGGCGGTTAGTGGAGTGTCTT
GAGACTGTGCTCAACAAGGCCCAGGAGCCTCCCAAGTCCAAGAAGGTGCAGCACTCCAATGCCA
AGAACGCCATCCTGTTTGAGACTATTAGCCTCATCATCCACTATGACAGTGAGCCCAACCTCCT
GGTCCGTGCCTGCAACCAGCTGGGCCAGTTCCTGCAGCACCGAGAGACGAACCTGCGCTACCTG
GCTCTGGAGAGCATGTGCACCCTGGCCAGCTCCGAGTTCTCCCACGAGGCTGTCAAGACCCACA
TTGATACTGTTATTAATGCCCTCAAGACTGAGCGGGACGTGAGTGTGAGGCAGCGGGCAGCTGA
TCTGCTGTATGCCATGTGTGACCGGAGCAATGCCAAGCAGATTGTATCAGAGATGCTGCGGTAC
CTAGAGACGGCTGACTATGCCATCCGAGAGGAGATTGTGCTGAAGGTGGCCATCTTGGCTGAGA
AGTATGCAGTGGACTACAGCTGGTATGTGGACACCATCCTCAACCTCATCCGCATTGCAGGCGA
CTATGTGAGCGAGGAGGTGTGGTACCGAGTGCTGCAGATCGTCACCAACCGTGATGATGTCCAG
GGTTATGCTGCCAAGACAGTGTTTGAGGCCCTCCAGGCCCCAGCCTGTCATGAGAACATGGTGA
AGGTCGGTGGCTACATCCTTGGGGAGTTTGGGAACTTGATTGCTGGGGACCCACGCTCCAGCCC
ACCTGTGCAGTTCTCACTGCTGCACTCCAAGTTCCACCTGTGCAGTGTGGCCACTCGTGCCTTG
CTGCTGTCCACCTACATCAAGTTCATCAACCTCTTCCCTGAGACCAAGGCCACCATCCAAGGTG
TTCTTCGTGCCGGCTCCCAGCTGCGCAATGCTGACGTGGAGCTACAGCAGCGGGCAGTGGAGTA
CCTCACCCTCAGCTCTGTAGCTAGCACCGATGTTTTGGCTACTGTGCTAGAAGAAATGCCCCCA
TTTCCTGAGCGGGAGTCATCCATTTTGGCTAAGCTGAAGCGTAAGAAGGGCCCTGGGGCAGCCA
GTGCCCTGGATGACAGCCGCAGGGACACCAGCAGCAATGACATCAATGGGGGTGTGGAGCCCAC
CCCCAGCAATGTGTCAACCCCCTCACCCTCCGCGGACCTCTTGGGGCTGCGGGCAGCCCCTCCC
CCTGCTGCACCCCCAGCTCCTGTAGGCGGGAACCTCCTGGTGGATGTTTTCTCTGACGGCCCCA
CTGCACAGCCCAGCCTGGGTCCCACCCCTGAGGAGGCCTTCCTCAGCCCAGGTCCTGAGGACAT
AGGTCCTCCCATTCCAGAAGCAGATGAACTGCTGAATAAGTTCGTGTGTAAGAATAGTGGGGTC
TTGTTTGAGAACCAGCTGCTGCAGATCGGAGTCAAGTCTGAGTTCCGGCAGAACCTGGGCCGCA
TGTATCTCTTCTATGGCAACAAGACTTCTGTGCAGTTCCAGAGCTTCTTGCCCACCGTGGTCCA
CCCTGGGGACCTCCAGACTCAGCTGGCGGTGCAGACCAAGCGTGTAGCTGCACAAGTGGACGGT
GGCGCACAGGTGCAGCAAGTACTCAACATTGAGTGTCTGCGAGACTTCTTGACGCCACCACTGC
TGTCGGTGCGCTTCCGGTACGGTGGCACCGCCCAGTCCCTCACTCTGAAGCTCCCAGTGACCAT
CAACAAATTCTTCCAGCCCACAGAGATGGCCGCCCAGGACTTTTTCCAGCGCTGGAAGCAGCTG
AGCCTCCCCCTGCAGGAGGCACAGAAAATCTTCAAAGCCAACCACCCCATGGATGCTGAAGTCA
CAAAGGCCAAGCTTCTGGGGTTTGGCTCTGCTCTTCTGGACAATGTGGATCCCAACCCTGAGAA
CTTTGTGGGTGCTGGAATCATCCAGACGAAAGCCCTGCAGGTGGGGTGTCTGCTTCGACTGGAG
CCCAATGCCCAGGCCCAAATGTACCGCCTAACCCTGCGCACCAGCAAAGAGCCTGTGTCCCGTC
ACTTATGTGAGCTGCTGGCCCAGCAGTTCTGAGCCCTGGACTTGCCCTGGGATATGGCCGGTGC
CAGGCAGCCCTGAGATGGAGGCAGCTGTGGTGGAGGGGGACAGCGAGGGGACCTCCAGTGGTGA
CAGCAAAGACCCCAGGGATGGGGGCATGCCTGGCGCGTCCTCTGGCCTTTGTATTTTATTTTTG
TTCATCTGCTGCTGTTTACATTCTGGGGGGTCAAGGGAAGCACCCTCCCTTCCTTGTCCCCCGA
AGCACAGAGGGGAGGGGGGCCGGGGAAGTAGGTACCTCCTCCCCTCCCCCTCCCTCCTTTTCAC
CCTCCTCCCTCCCTCCCTCTCCCCGTCCAGGGGCCGTGTATTATTGTGAGCGAATAAACAGAGA
GACGCTAATATTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100981	(Get FASTA)	NCBI Sequence Viewer
	XP_006229126	(Get FASTA)	NCBI Sequence Viewer
	XP_006229127	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM07441	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001100981 ⟸ NM_001107511

- UniProtKB:

D3ZUY8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLF
IFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFM
CLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARV
VHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPW
LSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHY
DSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVS
VRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILN
LIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIA
GDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVEL
QQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAASALDDSRRDTSSNDI
NGGVEPTPSNVSTPSPSADLLGLRAAPPPAAPPAPVGGNLLVDVFSDGPTAQPSLGPTPEEAFL
SELEPPAPESPMTLLADPAPAADPGPEDIGPPIPEADELLNKFVCKNSGVLFENQLLQIGVKSE
FRQNLGRMYLFYGNKTSVQFQSFLPTVVHPGDLQTHLAVQTKRVAAQVDGGAQVQQVLNIECLR
DFLTPPLLSVRFRYGGTAQSLTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPLQEAQKIFKAN
HPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRT
SKEPVSRHLCELLAQQF

hide sequence

RefSeq Acc Id:

XP_006229127 ⟸ XM_006229065

- Peptide Label:

isoform X2

- Sequence:

show sequence

MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLF
IFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFM
CLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARV
VHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPW
LSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHY
DSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVS
VRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILN
LIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIA
GDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVEL
QQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAASALDDSRRDTSSNDI
NGGVEPTPSNVSTPSPSADLLGLRAAPPPAAPPAPVGGNLLVDVFSDGPTAQPSLGPTPEEAFL
SPGPEDIGPPIPEADELLNKFVCKNSGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQS
FLPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGTAQSLT
LKLPVTINKFFQPTEMAAQDFFQRWKQLSLPLQEAQKIFKANHPMDAEVTKAKLLGFGSALLDN
VDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELLAQQF

hide sequence

RefSeq Acc Id:

XP_006229126 ⟸ XM_006229064

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLF
IFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFM
CLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARV
VHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPW
LSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHY
DSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVS
VRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILN
LIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIA
GDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVEL
QQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAASALDDSRRDTSSNDI
NGGVEPTPSNVSTPSPSADLLGLRAAPPPAAPPAPVGGNLLVDVFSDGPTAQPSLGPTPEEAFL
SELEPPAPESPMTLLADPAPAADPGPEDIGPPIPEADELLNKFVCKNSGVLFENQLLQIGVKSE
FRQNLGRMYLFYGNKTSVQFQSFLPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLR
DFLTPPLLSVRFRYGGTAQSLTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPLQEAQKIFKAN
HPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRT
SKEPVSRHLCELLAQQF

hide sequence

RefSeq Acc Id:

ENSRNOP00000020304 ⟸ ENSRNOT00000020304

Protein Domains

Alpha_adaptinC2

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Damaging Variants

Assembly: Rnor_5.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
1	101966589	101966590	C	T	snv	SBH/Ygl (KNAW), SBH/Ygl (MCW)

Assembly: Rnor_6.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
1	100901971	100901972	C	T	snv	SBH/Ygl (RGD), SBH/Ygl (MCW)

Assembly: RGSC_v3.4

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
1	95379127	95379128	C	T	snv	SBH/Ygl (ICL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306254	AgrOrtholog
Ensembl Genes	ENSRNOG00000026243	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000020304	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020304	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	1.25.10.10	UniProtKB/TrEMBL
	3.30.310.10	UniProtKB/TrEMBL
InterPro	AP2_complex_asu	UniProtKB/TrEMBL
	ARM-like	UniProtKB/TrEMBL
	ARM-type_fold	UniProtKB/TrEMBL
	Calthrin/coatomer_app_sub_C	UniProtKB/TrEMBL
	Clathrin/coatomer_adapt-like_N	UniProtKB/TrEMBL
	Clathrin/coatomer_app_Ig-like	UniProtKB/TrEMBL
	Clathrin_a-adaptin_app_sub_C	UniProtKB/TrEMBL
	Clathrin_a/b/g-adaptin_app_Ig	UniProtKB/TrEMBL
	TBP_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:308578	UniProtKB/TrEMBL
NCBI Gene	308578	ENTREZGENE
Pfam	Adaptin_N	UniProtKB/TrEMBL
	Alpha_adaptin_C	UniProtKB/TrEMBL
	Alpha_adaptinC2	UniProtKB/TrEMBL
PhenoGen	Ap2a1	PhenoGen
PIRSF	AP2_complex_alpha	UniProtKB/TrEMBL
SMART	Alpha_adaptinC2	UniProtKB/TrEMBL
Superfamily-SCOP	AP2_adap_app	UniProtKB/TrEMBL
	ARM-type_fold	UniProtKB/TrEMBL
	Clath_adapt	UniProtKB/TrEMBL
UniProt	D3ZUY8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-03	Ap2a1	adaptor related protein complex 2 subunit alpha 1	Ap2a1	adaptor-related protein complex 2, alpha 1 subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-25	Ap2a1	adaptor-related protein complex 2, alpha 1 subunit	Ap2a1	adaptor protein complex AP-2, alpha 1 subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Ap2a1	adaptor protein complex AP-2, alpha 1 subunit	Ap2a1_predicted	adaptor protein complex AP-2, alpha 1 subunit (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Ap2a1_predicted	adaptor protein complex AP-2, alpha 1 subunit (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

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RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)