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Gene: Hbb (hemoglobin subunit beta) Rattus norvegicus
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Symbol: Hbb
Name: hemoglobin subunit beta
Description: Exhibits hemoglobin alpha binding activity and hemoglobin beta binding activity. Contributes to oxygen binding activity. Involved in glutathione metabolic process; oxygen transport; and protein heterooligomerization. Localizes to the hemoglobin complex. Biomarker of anemia. Human ortholog(s) of this gene implicated in several diseases, including acute chest syndrome; congenital hemolytic anemia (multiple); polycythemia (multiple); sickle cell anemia; and thalassemia (multiple). Orthologous to several human genes including HBB (hemoglobin subunit beta); PARTICIPATES IN malaria pathway; sleeping sickness pathway; INTERACTS WITH (RS)-amphetamine; 1,2-dimethylhydrazine; 1,3,5-trinitro-1,3,5-triazinane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: beta-1-globin; Hemoglobin beta; hemoglobin beta chain complex; hemoglobin beta chain, major-form; hemoglobin beta-1 chain; hemoglobin subunit beta-1; hemoglobin, beta; III beta-1 globin; III beta-2 globin
Orthologs:
Homo sapiens (human) : HBB (hemoglobin subunit beta)  HGNC  Alliance
Mus musculus (house mouse) : Hbb-b1 (hemoglobin, beta adult major chain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hbb (hemoglobin subunit beta)
Canis lupus familiaris (dog) : LOC609402 (hemoglobin subunit beta-like)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01168,971,269 - 168,972,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01175,134,672 - 175,136,083 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41161,618,782 - 161,620,193 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11161,666,147 - 161,701,483 (-)NCBI
Celera1156,261,276 - 156,262,687 (-)NCBICelera
Cytogenetic Map1q32NCBI
RH 3.4 Map11291.6RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hbb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2783
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.