Vom2r37 (vomeronasal 2 receptor, 37) - Rat Genome Database

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Gene: Vom2r37 (vomeronasal 2 receptor, 37) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r37
Name: vomeronasal 2 receptor, 37
RGD ID: 1597332
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC690356; similar to putative pheromone receptor (Go-VN5); vomeronasal 2 receptor 37
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81102,394,607 - 102,456,272 (+)NCBIGRCr8
mRatBN7.2193,257,993 - 93,318,774 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl193,257,993 - 93,318,667 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx198,654,677 - 98,704,600 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01107,127,357 - 107,177,279 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01100,419,956 - 100,469,875 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0198,989,754 - 99,135,977 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl198,915,867 - 99,146,038 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01100,067,149 - 100,207,955 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4193,212,573 - 93,270,754 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera187,564,444 - 87,611,956 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
Additional References at PubMed
PMID:17382427  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:120
Count of miRNA genes:93
Interacting mature miRNAs:104
Transcripts:ENSRNOT00000056515
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1101228864146228864Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1102359314153680016Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)192683681137683681Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)197582336142582336Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1101594089146594089Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1100345976145345976Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat

Markers in Region
RH130226  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01100,132,034 - 100,132,773UniSTSRnor5.0
Cytogenetic Map1q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 4 29 14 17 4 5 4 2 23 13 23 3 25 13

Sequence


Ensembl Acc Id: ENSRNOT00000023732   ⟹   ENSRNOP00000023732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl198,915,867 - 99,146,038 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000056515   ⟹   ENSRNOP00000053355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl193,257,993 - 93,318,667 (+)Ensembl
Rnor_6.0 Ensembl198,989,754 - 99,135,977 (-)Ensembl
RefSeq Acc Id: NM_001099487   ⟹   NP_001092957
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81102,403,937 - 102,455,279 (+)NCBI
mRatBN7.2193,267,323 - 93,318,667 (+)NCBI
Rnor_6.0198,989,754 - 99,135,977 (-)NCBI
Rnor_5.01100,067,149 - 100,207,955 (-)NCBI
RGSC_v3.4193,212,573 - 93,270,754 (+)RGD
Celera187,564,444 - 87,611,956 (+)RGD
Sequence:
RefSeq Acc Id: XM_039091443   ⟹   XP_038947371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81102,398,234 - 102,456,272 (+)NCBI
mRatBN7.2193,262,699 - 93,318,774 (+)NCBI
RefSeq Acc Id: XM_039091454   ⟹   XP_038947382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81102,394,607 - 102,456,272 (+)NCBI
mRatBN7.2193,257,993 - 93,318,774 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001092957 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947371 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947382 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000053355.4
RefSeq Acc Id: NP_001092957   ⟸   NM_001099487
- UniProtKB: A6JAG7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023732   ⟸   ENSRNOT00000023732
Ensembl Acc Id: ENSRNOP00000053355   ⟸   ENSRNOT00000056515
RefSeq Acc Id: XP_038947382   ⟸   XM_039091454
- Peptide Label: isoform X2
- UniProtKB: F1LZV3 (UniProtKB/TrEMBL),   A6JAG7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947371   ⟸   XM_039091443
- Peptide Label: isoform X1
Protein Domains
G-protein coupled receptors family 3 profile

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1597332 AgrOrtholog
BioCyc Gene G2FUF-59870 BioCyc
Ensembl Genes ENSRNOG00000043280 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000056515.4 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene 690356 ENTREZGENE
PANTHER PTHR24061 UniProtKB/TrEMBL
  VOMERONASAL 2, RECEPTOR 57-RELATED UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vom2r37 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000043280 RatGTEx
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A6JAG7 ENTREZGENE, UniProtKB/TrEMBL
  F1LZV3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Vom2r37  vomeronasal 2 receptor, 37  LOC687816  similar to putative pheromone receptor (Go-VN5)  Data merged from RGD:1596287 1643240 APPROVED
2008-07-23 Vom2r37  vomeronasal 2 receptor, 37  LOC690356  similar to putative pheromone receptor (Go-VN5)  Symbol and Name updated 1299863 APPROVED
2006-11-20 LOC690356  similar to putative pheromone receptor (Go-VN5)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC687816  similar to putative pheromone receptor (Go-VN5)      Symbol and Name status set to provisional 70820 PROVISIONAL