Gene: Acer3 (alkaline ceramidase 3) Rattus norvegicus
Symbol: Acer3
Name: alkaline ceramidase 3
Description: ENCODES a protein that exhibits dihydroceramidase activity (ortholog); N-acylsphingosine amidohydrolase activity (ortholog); phytoceramidase activity (ortholog); INVOLVED IN ceramide catabolic process (ortholog); inflammatory response (ortholog); myelination (ortholog); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; ASSOCIATED WITH melanoma (ortholog); Progressive Leukodystrophy, Early Childhood-Onset (ortholog); FOUND IN integral component of endoplasmic reticulum membrane (ortholog); integral component of Golgi membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; endosulfan
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC499210; Phca; phytoceramidase, alkaline; RGD1561254; similar to Alkaline phytoceramidase (aPHC) (Alkaline ceramidase)
Homo sapiens (human) : ACER3 (alkaline ceramidase 3)  HGNC  Alliance
Mus musculus (house mouse) : Acer3 (alkaline ceramidase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acer3 (alkaline ceramidase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ACER3 (alkaline ceramidase 3)
Canis lupus familiaris (dog) : ACER3 (alkaline ceramidase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acer3 (alkaline ceramidase 3)
Sus scrofa (pig) : ACER3 (alkaline ceramidase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01163,160,987 - 163,263,621 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01169,367,775 - 169,469,576 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41155,455,466 - 155,556,319 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1150,595,013 - 150,696,477 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Acer3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561254
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-02-05
Status: ACTIVE