Advanced Search (OLGA)

Gene: Trim3 (tripartite motif-containing 3) Rattus norvegicus

Analyze

Symbol:

Trim3

Name:

tripartite motif-containing 3

RGD ID:

70074

Description:

Predicted to enable identical protein binding activity and ubiquitin protein ligase activity. Involved in regulation protein catabolic process at postsynapse. Is active in glutamatergic synapse and postsynapse. Orthologous to human TRIM3 (tripartite motif containing 3); INTERACTS WITH ammonium chloride; bisphenol A; cocaine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Berp; brain-expressed RING finger protein; ring finger protein 22; Rnf22; tripartite motif protein 3; tripartite motif-containing protein 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TRIM3 (tripartite motif containing 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Trim3 (tripartite motif-containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Trim3 (tripartite motif containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TRIM3 (tripartite motif containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TRIM3 (tripartite motif containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Trim3 (tripartite motif containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TRIM3 (tripartite motif containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TRIM3 (tripartite motif containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Trim3 (tripartite motif containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TRIM3 (tripartite motif containing 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Trim3 (tripartite motif-containing 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	trim3a (tripartite motif containing 3a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	trim3b (tripartite motif containing 3b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ncl-1	Alliance	DIOPT (PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nhl-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PANTHER)
Drosophila melanogaster (fruit fly):	tn	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	trim3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	169,362,751 - 169,385,430 (-)	NCBI		GRCr8
mRatBN7.2	1	159,950,921 - 159,973,600 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	159,944,908 - 159,973,600 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	167,973,469 - 167,996,177 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	175,159,470 - 175,182,183 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	168,061,185 - 168,083,921 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	170,441,662 - 170,464,341 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	170,441,639 - 170,464,341 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	177,447,514 - 177,470,193 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	163,337,614 - 163,362,846 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	163,433,089 - 163,458,323 (-)	NCBI
Celera	1	157,883,619 - 157,906,308 (-)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

neuronal ceroid lipofuscinosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

actinomycin D (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

camptothecin (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

clofibrate (ISO)

cocaine (EXP)

diazinon (ISO)

Dibutyl phosphate (ISO)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

ivermectin (ISO)

leflunomide (ISO)

Nutlin-3 (ISO)

pentanal (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

thiabendazole (EXP)

titanium dioxide (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

neural precursor cell proliferation (IEA,ISO)

positive regulation of toll-like receptor 3 signaling pathway (IEA,ISO)

proteasome-mediated ubiquitin-dependent protein catabolic process (IBA)

protein K63-linked ubiquitination (IEA,ISO)

protein polyubiquitination (IBA)

protein transport (IEA)

protein ubiquitination (ISO)

regulation protein catabolic process at postsynapse (IDA,IEP,IMP)

Cellular Component

cytoplasm (ISO)

dendrite (IEA)

early endosome (IEA)

glutamatergic synapse (IDA,IEP,IMP)

Golgi apparatus (IEA,ISO)

postsynapse (IDA,IEP)

Molecular Function

identical protein binding (IEA,ISO)

protein binding (IPI,ISO)

ubiquitin protein ligase activity (IBA,IEA,ISO)

ubiquitin-protein transferase activity (ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Cloning and characterization of a novel RING finger protein that interacts with class V myosins.	El-Husseini AE and Vincent SR, J Biol Chem 1999 Jul 9;274(28):19771-7.
2.	BERP, a novel ring finger protein, binds to alpha-actinin-4.	El-Husseini AE, etal., Biochem Biophys Res Commun 2000 Jan 27;267(3):906-11.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Degradation of postsynaptic scaffold GKAP and regulation of dendritic spine morphology by the TRIM3 ubiquitin ligase in rat hippocampal neurons.	Hung AY, etal., PLoS One. 2010 Mar 24;5(3):e9842. doi: 10.1371/journal.pone.0009842.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:11331580	PMID:16338934	PMID:21700703	PMID:24393003	PMID:30053369	PMID:32357304

Genomics

Comparative Map Data

Trim3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	169,362,751 - 169,385,430 (-)	NCBI		GRCr8
mRatBN7.2	1	159,950,921 - 159,973,600 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	159,944,908 - 159,973,600 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	167,973,469 - 167,996,177 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	175,159,470 - 175,182,183 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	168,061,185 - 168,083,921 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	170,441,662 - 170,464,341 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	170,441,639 - 170,464,341 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	177,447,514 - 177,470,193 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	163,337,614 - 163,362,846 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	163,433,089 - 163,458,323 (-)	NCBI
Celera	1	157,883,619 - 157,906,308 (-)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

TRIM3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	6,448,613 - 6,474,459 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	6,448,613 - 6,474,459 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	6,469,843 - 6,495,689 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	6,426,419 - 6,451,781 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	6,426,419 - 6,451,781	NCBI
Celera	11	6,588,902 - 6,614,265 (-)	NCBI		Celera
Cytogenetic Map	11	p15.4	NCBI
HuRef	11	6,128,913 - 6,154,761 (-)	NCBI		HuRef
CHM1_1	11	6,468,976 - 6,494,812 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	6,507,075 - 6,532,930 (-)	NCBI		T2T-CHM13v2.0

Trim3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	105,253,670 - 105,282,805 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	105,253,670 - 105,282,778 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	105,604,463 - 105,633,574 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	105,604,463 - 105,633,571 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	112,758,984 - 112,782,013 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	105,484,291 - 105,507,320 (-)	NCBI		MGSCv36	mm8
Celera	7	105,881,750 - 105,896,856 (-)	NCBI		Celera
Cytogenetic Map	7	E3	NCBI
cM Map	7	55.91	NCBI

Trim3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	22,181,857 - 22,207,244 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	22,181,999 - 22,207,244 (-)	NCBI	ChiLan1.0	ChiLan1.0

TRIM3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	8,885,639 - 8,910,986 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	8,849,520 - 8,874,856 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	6,580,491 - 6,605,854 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	6,263,961 - 6,289,331 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	6,264,376 - 6,281,033 (-)	Ensembl	panpan1.1		panPan2

TRIM3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	29,766,086 - 29,782,573 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	29,766,094 - 29,782,538 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	29,467,945 - 29,492,844 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	30,592,205 - 30,617,117 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	30,592,207 - 30,617,114 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	29,913,100 - 29,937,976 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	30,078,929 - 30,103,828 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	30,274,212 - 30,299,108 (-)	NCBI		UU_Cfam_GSD_1.0

Trim3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	56,151,134 - 56,174,358 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936842	501,127 - 524,347 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936842	494,460 - 524,305 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIM3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	3,272,798 - 3,282,366 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	3,256,915 - 3,281,846 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	3,915,403 - 3,940,027 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRIM3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	58,353,338 - 58,378,959 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	58,354,117 - 58,379,100 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	156,179,620 - 156,204,596 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trim3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624817	7,965,976 - 7,991,411 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624817	7,965,976 - 7,991,426 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	83
Count of miRNA genes:	66
Interacting mature miRNAs:	75
Transcripts:	ENSRNOT00000024850
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	131179947	176179947	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	137611478	182611478	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	153679879	198679879	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	132760429	191848948	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	153679879	205813246	Rat
8694166	Bw147	Body weight QTL 147	6.83	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	1	153788989	198788989	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	142582336	182383862	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	160573753	210707719	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	139442053	223964440	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	160573753	210707719	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	165278545	210278545	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	161077990	206077990	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	168063662	213063662	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	159894717	207261263	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	109493780	193400781	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	163992710	208992710	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	146080545	243492863	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	155359438	194575574	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	140833106	185833106	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	153679879	232414077	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	160574007	235238518	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	116099376	191260518	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	131243790	176243790	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
737974	Bp161	Blood pressure QTL 161		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	129182274	174182274	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	132760429	191848948	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	162753891	207753891	Rat
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	115183611	176289080	Rat
634315	Niddm45	Non-insulin dependent diabetes mellitus QTL 45	7.16		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	153680016	182383862	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
61379	Bp44	Blood pressure QTL 44	19.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	153680016	183564652	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	128019551	173019551	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	139442053	223964440	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	178317588	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	210707719	Rat
1576310	Schws2	Schwannoma susceptibility QTL 2		0.029	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	1	153788989	198788989	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	165707719	210707719	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	180021436	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132760429	191190115	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	140915717	185915717	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	132760429	191848948	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat
7411599	Foco11	Food consumption QTL 11	18.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	1	153788989	198788989	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	210707719	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031786	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092582	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092584	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC097992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF036255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000024850 ⟹ ENSRNOP00000024850

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	159,950,898 - 159,973,600 (-)	Ensembl
Rnor_6.0 Ensembl	1	170,441,639 - 170,464,341 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108664 ⟹ ENSRNOP00000087835

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	159,950,898 - 159,973,600 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114170 ⟹ ENSRNOP00000084221

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	159,944,908 - 159,973,600 (-)	Ensembl

RefSeq Acc Id:

NM_031786 ⟹ NP_113974

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	169,362,751 - 169,385,430 (-)	NCBI
mRatBN7.2	1	159,950,921 - 159,973,600 (-)	NCBI
Rnor_6.0	1	170,441,662 - 170,464,341 (-)	NCBI
Rnor_5.0	1	177,447,514 - 177,470,193 (-)	NCBI
RGSC_v3.4	1	163,337,614 - 163,362,846 (-)	RGD
Celera	1	157,883,619 - 157,906,308 (-)	NCBI

Sequence:

show sequence

CGCGGCGGCGGCGCCGGCGCGGGGACAGACGGAGGCGCGGGACGTGGGGCGGCGCCGCGGGCAG
GGCCGGGCGGACGAGCGCTGGCAGCGGGGGCAGCGCTGCGGGCCGCTCCGAGTGGCTGCAGTCC
GGGCCTTGCACTCCCATCCCGCTCCCACGCCGTGAGTGCGCGGCGCGGGCCCCAAGGGCTGGTG
TTAGTGGCAGGAACCATCTGTGGTCACCATGGCAAAGAGGGAGGACAGCCCTGGCCCGGAGGTG
CAGCCAATGGACAAGCAGTTTCTGGTATGCAGTATCTGCCTGGATCGGTACCGGTGCCCCAAAG
TTCTGCCTTGTCTACACACCTTCTGCGAAAGATGTCTCCAGAACTACATCCCTCCTCAGAGCCT
GACACTCTCGTGTCCAGTATGCCGGCAGACATCCATCCTCCCAGAACAGGGTGTCTCAGCCCTA
CAAAACAACTTCTTCATCAGCAGCCTCATGGAGGCCATGCAGCAGGCACCTGATGGGGCCCACG
ACCCTGAAGACCCCCACCCCCTCAGCGCAGTGGCTGGCCGCCCTCTCTCCTGCCCCAACCATGA
AGGCAAGACGATGGAGTTTTACTGTGAGGCCTGTGAGACTGCCATGTGTGGTGAGTGCCGCGCA
GGGGAGCACCGTGAACACGGCACAGTGCTGTTGCGGGACGTGGTGGAGCAGCACAAGGCAGCTC
TACAGCGCCAGCTTGAAGCTGTGCGTGGCCGATTGCCACAGCTGTCTGCAGCTATCGCCTTGGT
TGGGGGCATCAGCCAGCAGCTGCAAGAGCGCAAGGCAGAGGCCCTGGCCCAGATAAGTGCAGCC
TTTGAGGACCTGGAGCAAGCTCTGCAGCAGCGCAAGCAGGCTCTGGTCAGCGACTTGGAGAGCA
TTTGTGGGGCCAAGCAGAAGGTGTTGCAGACACAGTTAGACACACTGCGCCAGGGTCAGGAACA
CATTGGCAGTAGCTGCAGCTTTGCAGAGCAGGCACTGAGACTGGGCTCTGCCCCTGAGGTTTTG
CTAGTAAGAAAGCACATGCGAGAGAGGCTGGCTGCTCTGGCAGCTCAGGCCTTCCCAGAAAGGC
CCCATGAGAATGCACAGCTGGAACTGGTCCTTGAAGTAGATGGGTTGCGGAGATCGGTGCTCAA
TCTGGGTGCACTGCTCACCACCAGTGCTGCTGCACACGAGACAGTGGCCACCGGCGAGGGCCTG
CGCCAGGCACTGGTTGGCCAGCCTGCCTCACTCACTGTCACCACCAAAGACAAAGATGGGCGGC
TGGTGCGCACGGGCAGCGCAGAGCTGTGTGCAGAGATCACTGGCCCCGATGGCATGCGCCTTGC
GGTACCGGTGGTGGACCACAAAAATGGCACATATGAGCTGGTGTACACAGCACGTACAGAAGGC
GACCTGCTCCTCTCAGTGCTGCTCTATGGACAGCCGGTGCGTGGCAGCCCTTTCCGTGTGCGTG
CCCTGAGACCCGGAGACTTGCCACCTTCCCCAGATGATGTGAAGCGCCGGGTCAAGTCTCCCGG
TGGTCCTGGCAGTCATGTGCGCCAGAAGGCAGTGCGTAGGCCGAGCTCCATGTACAGCACCGGT
GGCAAACGGAAAGACAATCCAATTGTGGATGAACTCGTCTTTCGTGTTGGCAGTCGTGGAAGGG
AGAAAGGTGAATTCACCAATTTACACCCGCTGTCCGCTGCTAGCAGTGGCCGAATAGTGGTAGC
AGACAGCAACAACCAATGTATTCAGGTTTTCTCCAATGAGGGCCAGTTCAAGTTCCGATTTGGA
GTCCGTGGGCGCTCGCCTGGGCAACTACAGCGTCCTACGGGTGTGGCAGTGGACACCAATGGAG
ACATTATTGTGGCAGACTATGACAACCGTTGGGTCAGCATCTTCTCTCCTGAGGGCAAGTTCAA
GACCAAAATTGGAGCTGGCCGCCTCATGGGGCCCAAGGGAGTGGCTGTGGACCGGAATGGGCAT
ATCATTGTGGTGGATAACAAGTCTTGCTGTGTCTTCACCTTCCAGCCCAATGGCAAGCTTGTTG
GGCGTTTTGGAGGCCGTGGGGCCACTGACCGCCACTTCGCAGGGCCCCACTTTGTGGCTGTGAA
CAACAAGAATGAGATTGTAGTAACGGATTTCCACAACCATTCAGTGAAGGTGTACAGTGCTGAT
GGAGAGTTCCTCTTCAAATTTGGCTCACATGGCGAGGGCAATGGACAGTTCAATGCCCCCACGG
GAGTAGCTGTGGATTCCAATGGAAACATCATCGTGGCTGACTGGGGCAATAGTCGCATACAGGT
ATTCGACAGCTCTGGTTCCTTCCTGTCCTATATCAACACGTCTGCAGAGCCACTGTATGGCCCA
CAGGGCTTGGCATTGACCTCGGATGGCCACGTAGTAGTGGCTGATGCTGGCAACCACTGCTTTA
AGGCCTATCGATACCTCCAGTAGCTGCACAAGGGCCCTGCTTGGCTCATGGAGGGACGGACATA
GGGGTGATTGGACAAGAGGGTCTGGCTAAGAGGTGGGCCAGACCCGGCAGCACTGAATGTGGGC
GTGGGCATGGATGTGCCCAATGCCCTTCCCTTCCTCCCCAACCCCACGGTTGCACTTTATTTAT
TCGGTTCTTGCTTTGGTGACTGGGTGGGCCTGGACTGGTCCCAAGGATGTGTGCAGAGCTTCAC
CCTAACTCCTTTACACACCCTCCCTTACACCCTCAGTCTGCTCTCTGACCCCCAGCCTGGGCCA
GAACAGCCTCTTACTTCAGAAGTCCCTCTGGTTGGCTCCCTAACACCCCATACACACTGACAGA
GACAGCAATACCCCACCCCATATTAAATAAATGTGTTCGCCAAGGTGGGAATTCCTGGCTGATG
CGGTCTCAAA

hide sequence

RefSeq Acc Id:

XM_039092582 ⟹ XP_038948510

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	169,362,753 - 169,385,424 (-)	NCBI
mRatBN7.2	1	159,950,923 - 159,973,592 (-)	NCBI

RefSeq Acc Id:

XM_039092584 ⟹ XP_038948512

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	169,362,753 - 169,385,424 (-)	NCBI
mRatBN7.2	1	159,950,923 - 159,973,593 (-)	NCBI

RefSeq Acc Id:

XM_039092585 ⟹ XP_038948513

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	169,362,753 - 169,385,411 (-)	NCBI
mRatBN7.2	1	159,950,923 - 159,973,575 (-)	NCBI

RefSeq Acc Id:

XM_039092586 ⟹ XP_038948514

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	169,362,753 - 169,372,063 (-)	NCBI
mRatBN7.2	1	159,950,923 - 159,973,594 (-)	NCBI

RefSeq Acc Id:

XM_063275581 ⟹ XP_063131651

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	169,362,753 - 169,385,411 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_113974	(Get FASTA)	NCBI Sequence Viewer
	XP_038948510	(Get FASTA)	NCBI Sequence Viewer
	XP_038948512	(Get FASTA)	NCBI Sequence Viewer
	XP_038948513	(Get FASTA)	NCBI Sequence Viewer
	XP_038948514	(Get FASTA)	NCBI Sequence Viewer
	XP_063131651	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC17997	(Get FASTA)	NCBI Sequence Viewer
	EDM18030	(Get FASTA)	NCBI Sequence Viewer
	EDM18031	(Get FASTA)	NCBI Sequence Viewer
	EDM18032	(Get FASTA)	NCBI Sequence Viewer
	EDM18033	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000024850.3
	ENSRNOP00000084221.1
	ENSRNOP00000087835.1
GenBank Protein	O70277	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_113974 ⟸ NM_031786

- UniProtKB:

O70277 (UniProtKB/Swiss-Prot), A6I7K0 (UniProtKB/TrEMBL), G3V8D6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAKREDSPGPEVQPMDKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQ
TSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSAVAGRPLSCPNHEGKTMEFYCE
ACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQE
RKAEALAQISAAFEDLEQALQQRKQALVSDLESICGAKQKVLQTQLDTLRQGQEHIGSSCSFAE
QALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSA
AAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELCAEITGPDGMRLAVPVVDHKNG
TYELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQK
AVRRPSSMYSTGGKRKDNPIVDELVFRVGSRGREKGEFTNLHPLSAASSGRIVVADSNNQCIQV
FSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLM
GPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTD
FHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLS
YINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000024850 ⟸ ENSRNOT00000024850

RefSeq Acc Id:	XP_038948514 ⟸ XM_039092586
- Peptide Label:	isoform X3
- UniProtKB:	O70277 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038948512 ⟸ XM_039092584
- Peptide Label:	isoform X1
- UniProtKB:	O70277 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038948510 ⟸ XM_039092582
- Peptide Label:	isoform X1
- UniProtKB:	O70277 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038948513 ⟸ XM_039092585
- Peptide Label:	isoform X1
- UniProtKB:	O70277 (UniProtKB/Swiss-Prot)

Ensembl Acc Id:

ENSRNOP00000084221 ⟸ ENSRNOT00000114170

Ensembl Acc Id:

ENSRNOP00000087835 ⟸ ENSRNOT00000108664

RefSeq Acc Id:	XP_063131651 ⟸ XM_063275581
- Peptide Label:	isoform X2
- UniProtKB:	O70277 (UniProtKB/Swiss-Prot), A6I7K0 (UniProtKB/TrEMBL), G3V8D6 (UniProtKB/TrEMBL)

Protein Domains

B box-type RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O70277-F1-model_v2	AlphaFold	O70277	1-744	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690287

Promoter ID:

EPDNEW_R812

Type:

initiation region

Name:

Trim3_1

Description:

tripartite motif-containing 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	170,464,363 - 170,464,423	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:70074	AgrOrtholog
BioCyc Gene	G2FUF-58014	BioCyc
Ensembl Genes	ENSRNOG00000018356	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024850.6	UniProtKB/TrEMBL
	ENSRNOT00000108664.1	UniProtKB/TrEMBL
	ENSRNOT00000114170.1	UniProtKB/TrEMBL
Gene3D-CATH	2.120.10.30	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	6-blade_b-propeller_TolB-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Bbox_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Filamin/ABP280_repeat-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Filamin/ABP280_rpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_E-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NHL_repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TRIM-NHL_E3_ligases	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_B-box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_C3HC4_RING-type	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:83616	UniProtKB/Swiss-Prot
NCBI Gene	Trim3	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TRIPARTITE MOTIF-CONTAINING PROTEIN 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Filamin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NHL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-B_box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-C3HC4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Trim3	PhenoGen
PROSITE	FILAMIN_REPEAT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NHL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_BBOX	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000018356	RatGTEx
SMART	BBC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	BBOX	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IG_FLMN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	B-box zinc-binding domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NHL repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RING/U-box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF81296	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC207339
UniProt	A0A8I5ZWR8_RAT	UniProtKB/TrEMBL
	A0A8I6A8J7_RAT	UniProtKB/TrEMBL
	A6I7K0	ENTREZGENE, UniProtKB/TrEMBL
	G3V8D6	ENTREZGENE, UniProtKB/TrEMBL
	O70277	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-31	Trim3	tripartite motif-containing 3	Trim3	tripartite motif protein 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Trim3	tripartite motif protein 3			Symbol and Name status set to approved	70586	APPROVED
2002-02-26	Trim3	tripartite motif protein 3			Symbol and Name updated to reflect Human and Mouse nomenclature	70292	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains an N-terminal RING finger, a B-box zinc finger, a coiled-coil (RBCC domain), and a unique C-terminal beta-propeller domain	68906
gene_expression	highly expressed in brain	68906
gene_function	binds to the class V myosin Myr6 (myosin Vb) tail	68906
gene_process	involved in protein dimerization	68906
gene_process	may have a role in myosin V-mediated cargo transport	68906

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar