TRIM3 (tripartite motif containing 3) - Rat Genome Database

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Gene: TRIM3 (tripartite motif containing 3) Canis lupus familiaris
Analyze
Symbol: TRIM3
Name: tripartite motif containing 3
RGD ID: 12140699
Description: ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); transferase activity (inferred); INVOLVED IN regulation protein catabolic process at postsynapse (ortholog); ASSOCIATED WITH autistic disorder (ortholog); neuronal ceroid lipofuscinosis (ortholog); FOUND IN glutamatergic synapse (ortholog); Golgi apparatus (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tripartite motif-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12129,766,086 - 29,782,573 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2129,766,094 - 29,782,538 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2129,467,945 - 29,492,844 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02130,592,205 - 30,617,117 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2130,592,207 - 30,617,114 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12129,913,100 - 29,937,976 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02130,078,929 - 30,103,828 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02130,274,212 - 30,299,108 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRIM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12129,766,086 - 29,782,573 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2129,766,094 - 29,782,538 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2129,467,945 - 29,492,844 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02130,592,205 - 30,617,117 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2130,592,207 - 30,617,114 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12129,913,100 - 29,937,976 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02130,078,929 - 30,103,828 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02130,274,212 - 30,299,108 (-)NCBIUU_Cfam_GSD_1.0
TRIM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,448,613 - 6,474,459 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,448,613 - 6,474,459 (-)EnsemblGRCh38hg38GRCh38
GRCh37116,469,843 - 6,495,689 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,426,419 - 6,451,781 (-)NCBINCBI36Build 36hg18NCBI36
Build 34116,426,419 - 6,451,781NCBI
Celera116,588,902 - 6,614,265 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef116,128,913 - 6,154,761 (-)NCBIHuRef
CHM1_1116,468,976 - 6,494,812 (-)NCBICHM1_1
T2T-CHM13v2.0116,507,075 - 6,532,930 (-)NCBIT2T-CHM13v2.0
Trim3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397105,253,670 - 105,282,805 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7105,253,670 - 105,282,778 (-)EnsemblGRCm39 Ensembl
GRCm387105,604,463 - 105,633,574 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,604,463 - 105,633,571 (-)EnsemblGRCm38mm10GRCm38
MGSCv377112,758,984 - 112,782,013 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367105,484,291 - 105,507,320 (-)NCBIMGSCv36mm8
Celera7105,881,750 - 105,896,856 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.91NCBI
Trim3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81169,362,751 - 169,385,430 (-)NCBIGRCr8
mRatBN7.21159,950,921 - 159,973,600 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1159,944,908 - 159,973,600 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1167,973,469 - 167,996,177 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01175,159,470 - 175,182,183 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01168,061,185 - 168,083,921 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01170,441,662 - 170,464,341 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1170,441,639 - 170,464,341 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01177,447,514 - 177,470,193 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41163,337,614 - 163,362,846 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11163,433,089 - 163,458,323 (-)NCBI
Celera1157,883,619 - 157,906,308 (-)NCBICelera
Cytogenetic Map1q32NCBI
Trim3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541422,181,857 - 22,207,244 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541422,181,999 - 22,207,244 (-)NCBIChiLan1.0ChiLan1.0
TRIM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v298,885,639 - 8,910,986 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1118,849,520 - 8,874,856 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,580,491 - 6,605,854 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,263,961 - 6,289,331 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,264,376 - 6,281,033 (-)Ensemblpanpan1.1panPan2
Trim3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494756,151,134 - 56,174,358 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936842501,127 - 524,347 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936842494,460 - 524,305 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl93,272,798 - 3,282,366 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.193,256,915 - 3,281,846 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.293,915,403 - 3,940,027 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1158,353,338 - 58,378,959 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl158,354,117 - 58,379,100 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038156,179,620 - 156,204,596 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trim3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248177,965,976 - 7,991,411 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248177,965,976 - 7,991,426 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TRIM3
186 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_038430351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038456518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038456519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038505689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038505690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038568899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038568900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038633065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038633066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_534038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000010416   ⟹   ENSCAFP00000009658
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2129,766,094 - 29,782,538 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000092594   ⟹   ENSCAFP00000045308
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2129,766,094 - 29,776,201 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845014376   ⟹   ENSCAFP00845011134
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2130,592,207 - 30,617,114 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845014420   ⟹   ENSCAFP00845011168
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2130,592,207 - 30,608,737 (-)Ensembl
RefSeq Acc Id: XM_038430351   ⟹   XP_038286279
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02130,592,205 - 30,617,117 (-)NCBI
RefSeq Acc Id: XM_038430352   ⟹   XP_038286280
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02130,592,205 - 30,616,918 (-)NCBI
RefSeq Acc Id: XM_038456518   ⟹   XP_038312446
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2129,467,945 - 29,492,844 (-)NCBI
RefSeq Acc Id: XM_038456519   ⟹   XP_038312447
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2129,467,945 - 29,492,645 (-)NCBI
RefSeq Acc Id: XM_038505689   ⟹   XP_038361617
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12129,913,100 - 29,937,976 (-)NCBI
RefSeq Acc Id: XM_038505690   ⟹   XP_038361618
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12129,913,100 - 29,937,771 (-)NCBI
RefSeq Acc Id: XM_038568899   ⟹   XP_038424827
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02130,274,212 - 30,299,108 (-)NCBI
RefSeq Acc Id: XM_038568900   ⟹   XP_038424828
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02130,274,212 - 30,298,909 (-)NCBI
RefSeq Acc Id: XM_038633065   ⟹   XP_038488993
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02130,078,929 - 30,103,828 (-)NCBI
RefSeq Acc Id: XM_038633066   ⟹   XP_038488994
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02130,078,929 - 30,103,629 (-)NCBI
Ensembl Acc Id: ENSCAFP00000045308   ⟸   ENSCAFT00000092594
Ensembl Acc Id: ENSCAFP00000009658   ⟸   ENSCAFT00000010416
RefSeq Acc Id: XP_038361617   ⟸   XM_038505689
RefSeq Acc Id: XP_038361618   ⟸   XM_038505690
RefSeq Acc Id: XP_038488993   ⟸   XM_038633065
RefSeq Acc Id: XP_038488994   ⟸   XM_038633066
RefSeq Acc Id: XP_038286279   ⟸   XM_038430351
- UniProtKB: A0A8C0RF81 (UniProtKB/TrEMBL),   A0A8C0K9C5 (UniProtKB/TrEMBL),   A0A8I3RVW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038286280   ⟸   XM_038430352
- UniProtKB: A0A8C0RF81 (UniProtKB/TrEMBL),   A0A8C0K9C5 (UniProtKB/TrEMBL),   A0A8I3RVW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038312446   ⟸   XM_038456518
- UniProtKB: A0A8C0RF81 (UniProtKB/TrEMBL),   A0A8C0K9C5 (UniProtKB/TrEMBL),   A0A8I3RVW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038312447   ⟸   XM_038456519
- UniProtKB: A0A8C0RF81 (UniProtKB/TrEMBL),   A0A8C0K9C5 (UniProtKB/TrEMBL),   A0A8I3RVW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424827   ⟸   XM_038568899
- UniProtKB: A0A8C0K9C5 (UniProtKB/TrEMBL),   A0A8C0RF81 (UniProtKB/TrEMBL),   A0A8I3RVW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424828   ⟸   XM_038568900
- UniProtKB: A0A8C0K9C5 (UniProtKB/TrEMBL),   A0A8C0RF81 (UniProtKB/TrEMBL),   A0A8I3RVW6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845011134   ⟸   ENSCAFT00845014376
Ensembl Acc Id: ENSCAFP00845011168   ⟸   ENSCAFT00845014420
Protein Domains
B box-type   B-box C-terminal   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006444 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030008044 UniProtKB/TrEMBL
  ENSCAFG00040020016 UniProtKB/TrEMBL
  ENSCAFG00845008173 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000010416.5 UniProtKB/TrEMBL
  ENSCAFT00000092594.2 UniProtKB/TrEMBL
  ENSCAFT00030014889.1 UniProtKB/TrEMBL
  ENSCAFT00040037023.1 UniProtKB/TrEMBL
  ENSCAFT00040037094.1 UniProtKB/TrEMBL
  ENSCAFT00845014376 ENTREZGENE
  ENSCAFT00845014376.1 UniProtKB/TrEMBL
  ENSCAFT00845014420.1 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.30 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro 6-blade_b-propeller_TolB-like UniProtKB/TrEMBL
  Bbox_C UniProtKB/TrEMBL
  Filamin/ABP280_repeat-like UniProtKB/TrEMBL
  Filamin/ABP280_rpt UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  NHL_repeat UniProtKB/TrEMBL
  TRIM-NHL_E3_ligases UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene TRIM3 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED UniProtKB/TrEMBL
  TRIPARTITE MOTIF-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
Pfam Filamin UniProtKB/TrEMBL
  NHL UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
PROSITE FILAMIN_REPEAT UniProtKB/TrEMBL
  NHL UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BBC UniProtKB/TrEMBL
  BBOX UniProtKB/TrEMBL
  IG_FLMN UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  NHL repeat UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A8C0K9C5 ENTREZGENE
  A0A8C0RF81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TBL8_CANLF UniProtKB/TrEMBL
  A0A8I3NJJ0_CANLF UniProtKB/TrEMBL
  A0A8I3RVW6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47813 ENTREZGENE