Gene: Actn4 (actinin alpha 4) Rattus norvegicus
Symbol: Actn4
Name: actinin alpha 4
Description: ENCODES a protein that exhibits protein N-terminus binding; protein-containing complex binding; actin filament binding (ortholog); INVOLVED IN regulation of apoptotic process; response to hypoxia; actin filament bundle assembly (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; Entamoebiasis pathway; ASSOCIATED WITH carcinoma (ortholog); Chemical and Drug Induced Liver Injury (ortholog); focal segmental glomerulosclerosis (ortholog); FOUND IN cytoplasm; neuron projection; nucleus; INTERACTS WITH 2,2,2-tetramine; 2,6-dinitrotoluene; 2-nitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha actinin 4; alpha actinin 4 between D1Rat178 and D1Rat97; alpha-actinin-4; F-actin cross-linking protein; non-muscle alpha-actinin 4
Homo sapiens (human) : ACTN4 (actinin alpha 4)  HGNC  Alliance
Mus musculus (house mouse) : Actn4 (actinin alpha 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Actn4 (actinin alpha 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTN4 (actinin alpha 4)
Canis lupus familiaris (dog) : ACTN4 (actinin alpha 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actn4 (actinin alpha 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0187,078,012 - 87,147,347 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0188,258,630 - 88,327,965 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4184,000,723 - 84,073,767 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1184,079,711 - 84,151,876 (-)NCBI
Celera178,572,890 - 78,641,919 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Actn4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61816
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2018-07-10
Status: ACTIVE