Nup62 (nucleoporin 62) - Rat Genome Database

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Gene: Nup62 (nucleoporin 62) Rattus norvegicus
Symbol: Nup62
Name: nucleoporin 62
RGD ID: 619938
Description: Enables kinesin binding activity. A structural constituent of nuclear pore. Involved in protein import into nucleus; regulation of protein import into nucleus; and spermatogenesis. Located in annulate lamellae and nuclear membrane. Part of nuclear pore. Human ortholog(s) of this gene implicated in primary biliary cholangitis and striatonigral degeneration. Orthologous to human NUP62 (nucleoporin 62); PARTICIPATES IN mRNA nuclear export pathway; RNA transport pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 62 kDa nucleoporin; Np62; nuclear pore glycoprotein 62; nuclear pore glycoprotein p62; nucleoporin Nup62
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2195,298,995 - 95,314,902 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,295,526 - 95,315,174 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,684,924 - 100,700,286 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,157,589 - 109,172,951 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,447,996 - 102,463,359 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01100,811,140 - 100,827,119 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,811,755 - 100,827,111 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,876,161 - 101,891,789 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,288,019 - 95,303,545 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,378,221 - 95,382,015 (+)NCBI
Celera189,561,555 - 89,576,634 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
atrazine  (ISO)
auramine O  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenthion  (ISO)
folic acid  (ISO)
folpet  (ISO)
furan  (EXP)
gentamycin  (EXP)
ivermectin  (ISO)
ketoconazole  (EXP)
leflunomide  (ISO)
leptomycin B  (EXP)
lycopene  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylephrine  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
propiconazole  (EXP)
rotenone  (ISO)
Salinomycin  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tauroursodeoxycholic acid  (EXP)
tetrachloromethane  (ISO)
thapsigargin  (EXP)
trichostatin A  (EXP,ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View

References - curated
# Reference Title Reference Citation
1. Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import. Ben-Efraim I and Gerace L, J Cell Biol. 2001 Jan 22;152(2):411-7.
2. Sequential recruitment of NPC proteins to the nuclear periphery at the end of mitosis. Bodoor K, etal., J Cell Sci. 1999 Jul;112 ( Pt 13):2253-64.
3. Regulation of mRNA trafficking by nuclear pore complexes. Bonnet A and Palancade B, Genes (Basel). 2014 Sep 2;5(3):767-91. doi: 10.3390/genes5030767.
4. Separate binding sites on nuclear transport factor 2 (NTF2) for GDP-Ran and the phenylalanine-rich repeat regions of nucleoporins p62 and Nsp1p. Clarkson WD, etal., J Mol Biol. 1996 Nov 8;263(4):517-24.
5. The gene encoding rat nuclear pore glycoprotein p62 is intronless. D'Onofrio M, etal., J Biol Chem 1991 Jun 25;266(18):11980-5.
6. Partial cDNA sequence encoding a nuclear pore protein modified by O-linked N-acetylglucosamine. D'Onofrio M, etal., Proc Natl Acad Sci U S A 1988 Dec;85(24):9595-9.
7. A biochemical and immunological comparison of nuclear and cytoplasmic pore complexes. Ewald A, etal., J Cell Sci. 1996 Jul;109 ( Pt 7):1813-24.
8. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex. Guan T, etal., Mol Biol Cell. 1995 Nov;6(11):1591-603.
10. Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins. Hu T, etal., J Cell Biol 1996 Aug;134(3):589-601.
11. Profile and clinical significance of anti-nuclear envelope antibodies found in patients with primary biliary cirrhosis: a multicenter study. Miyachi K, etal., J Autoimmun. 2003 May;20(3):247-54.
12. The mammalian RNA-binding protein Staufen2 links nuclear and cytoplasmic RNA processing pathways in neurons. Monshausen M, etal., Neuromolecular Med. 2004;6(2-3):127-44.
13. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein. Puls A, etal., Proc Natl Acad Sci U S A 1997 Jun 10;94(12):6191-6.
17. GOA pipeline RGD automated data pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Molecular architecture of the transport channel of the nuclear pore complex. Solmaz SR, etal., Cell. 2011 Oct 28;147(3):590-602. doi: 10.1016/j.cell.2011.09.034.
21. The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution. Ulrich A, etal., Mol Biol Cell. 2014 May;25(9):1484-92. doi: 10.1091/mbc.E13-12-0745. Epub 2014 Feb 26.
22. The molecular motor KIFC1 associates with a complex containing nucleoporin NUP62 that is regulated during development and by the small GTPase RAN. Yang WX, etal., Biol Reprod. 2006 Apr;74(4):684-90. Epub 2005 Dec 21.
Additional References at PubMed
PMID:1915414   PMID:1915419   PMID:2190987   PMID:7849178   PMID:8650207   PMID:8702753   PMID:9348540   PMID:10356400   PMID:10373430   PMID:10799545   PMID:11013214   PMID:11031258  
PMID:11244088   PMID:11489947   PMID:11755531   PMID:12477932   PMID:15572682   PMID:15625236   PMID:17098863   PMID:17882263   PMID:18809582   PMID:19166812   PMID:19581287   PMID:22683860  
PMID:23777819   PMID:24107630   PMID:25349423   PMID:26025361   PMID:28406021   PMID:29057768   PMID:37802024  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2195,298,995 - 95,314,902 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,295,526 - 95,315,174 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,684,924 - 100,700,286 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,157,589 - 109,172,951 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,447,996 - 102,463,359 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01100,811,140 - 100,827,119 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,811,755 - 100,827,111 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,876,161 - 101,891,789 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,288,019 - 95,303,545 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,378,221 - 95,382,015 (+)NCBI
Celera189,561,555 - 89,576,634 (+)NCBICelera
Cytogenetic Map1q22NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381949,906,825 - 49,929,504 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,906,825 - 49,929,764 (-)EnsemblGRCh38hg38GRCh38
GRCh371950,410,082 - 50,432,761 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,101,894 - 55,124,598 (-)NCBINCBI36Build 36hg18NCBI36
Build 341955,101,893 - 55,124,598NCBI
Celera1947,279,595 - 47,302,503 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,786,417 - 46,809,243 (-)NCBIHuRef
CHM1_11950,411,926 - 50,434,816 (-)NCBICHM1_1
T2T-CHM13v2.01952,906,960 - 52,929,639 (-)NCBIT2T-CHM13v2.0
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39744,465,512 - 44,481,260 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,465,512 - 44,480,236 (+)EnsemblGRCm39 Ensembl
GRCm38744,816,088 - 44,831,836 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl744,816,088 - 44,830,812 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,071,790 - 52,086,177 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,684,462 - 44,698,849 (+)NCBIMGSCv36mm8
Celera740,266,716 - 40,281,098 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.93NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_0049555591,030,894 - 1,032,462 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,012,919 - 1,033,465 (+)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan11957,943,134 - 57,965,715 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,919,731 - 46,942,318 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,835,593 - 55,858,165 (-)NCBIpanpan1.1PanPan1.1panPan2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.11106,636,282 - 106,661,250 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,219,723 - 106,244,693 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,157,688 - 107,182,656 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,157,675 - 107,182,663 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11106,829,847 - 106,854,818 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,472,003 - 106,496,982 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,312,293 - 107,337,261 (+)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_02440934922,072,538 - 22,095,600 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,690,567 - 3,713,719 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,690,728 - 3,713,819 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl654,921,627 - 54,923,227 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,921,627 - 54,945,705 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,696,590 - 50,727,405 (-)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1643,063,483 - 43,086,264 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl643,064,875 - 43,066,440 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607323,038,779 - 23,061,398 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla_female_1.0 EnsemblNW_0046248324,404,245 - 4,428,231 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,404,367 - 4,428,231 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Variants in Nup62
32 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:284
Count of miRNA genes:192
Interacting mature miRNAs:224
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)194494440117601394Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat

Markers in Region
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,314,575 - 95,314,767 (+)MAPPERmRatBN7.2
Rnor_6.01100,826,793 - 100,826,984NCBIRnor6.0
Rnor_5.01101,891,463 - 101,891,654UniSTSRnor5.0
RGSC_v3.4195,303,221 - 95,303,412UniSTSRGSC3.4
Celera189,576,310 - 89,576,501UniSTS
Cytogenetic Map1q22UniSTS


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
Medium 3 35 57 41 19 41 7 10 74 30 41 11 7
Low 8 1 1 5 1
Below cutoff


RefSeq Acc Id: ENSRNOT00000074847   ⟹   ENSRNOP00000067556
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,302,226 - 95,315,174 (+)Ensembl
Rnor_6.0 Ensembl1100,811,755 - 100,827,111 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117253   ⟹   ENSRNOP00000081212
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,295,526 - 95,315,174 (+)Ensembl
RefSeq Acc Id: NM_023098   ⟹   NP_075586
RefSeq Status: VALIDATED
Rat AssemblyChrPosition (strand)Source
mRatBN7.2195,299,536 - 95,314,900 (+)NCBI
Rnor_6.01100,811,755 - 100,827,117 (+)NCBI
Rnor_5.01101,876,161 - 101,891,789 (+)NCBI
RGSC_v3.4195,288,019 - 95,303,545 (+)RGD
Celera189,561,555 - 89,576,634 (+)RGD
RefSeq Acc Id: XM_006229150   ⟹   XP_006229212
Rat AssemblyChrPosition (strand)Source
mRatBN7.2195,298,995 - 95,314,902 (+)NCBI
Rnor_6.01100,811,140 - 100,827,119 (+)NCBI
Rnor_5.01101,876,161 - 101,891,789 (+)NCBI
RefSeq Acc Id: XM_006229151   ⟹   XP_006229213
Rat AssemblyChrPosition (strand)Source
mRatBN7.2195,301,710 - 95,314,902 (+)NCBI
Rnor_6.01100,813,942 - 100,827,119 (+)NCBI
Rnor_5.01101,876,161 - 101,891,789 (+)NCBI
RefSeq Acc Id: NP_075586   ⟸   NM_023098
- UniProtKB: A2VCW0 (UniProtKB/Swiss-Prot),   P17955 (UniProtKB/Swiss-Prot),   A6JAS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229212   ⟸   XM_006229150
- Peptide Label: isoform X1
- UniProtKB: A2VCW0 (UniProtKB/Swiss-Prot),   P17955 (UniProtKB/Swiss-Prot),   A6JAS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229213   ⟸   XM_006229151
- Peptide Label: isoform X1
- UniProtKB: A2VCW0 (UniProtKB/Swiss-Prot),   P17955 (UniProtKB/Swiss-Prot),   A6JAS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000067556   ⟸   ENSRNOT00000074847
RefSeq Acc Id: ENSRNOP00000081212   ⟸   ENSRNOT00000117253
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P17955-F1-model_v2 AlphaFold P17955 1-525 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690008
Promoter ID:EPDNEW_R532
Type:multiple initiation site
Description:nucleoporin 62
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Rat AssemblyChrPosition (strand)Source
Rnor_6.01100,811,726 - 100,811,786EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619938 AgrOrtholog
BioCyc Gene G2FUF-59751 BioCyc
Ensembl Genes ENSRNOG00000048733 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000074847 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000117253 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NSP1/NUP62 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleoporin_NSP1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:65274 UniProtKB/Swiss-Prot
Pfam Nsp1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nup62 PhenoGen
RatGTEx ENSRNOG00000048733 RatGTEx
  NUP62_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A2VCW0 UniProtKB/Swiss-Prot

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Nup62  nucleoporin 62    nuclear pore glycoprotein 62  Name updated 1299863 APPROVED
2002-08-07 Nup62  nuclear pore glycoprotein 62      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein 525 amino acid residues 728932