Folr1 (folate receptor alpha) - Rat Genome Database

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Gene: Folr1 (folate receptor alpha) Rattus norvegicus
Analyze
Symbol: Folr1
Name: folate receptor alpha
RGD ID: 71032
Description: Enables folic acid binding activity. Predicted to be involved in several processes, including circulatory system development; nervous system development; and regulation of signal transduction. Predicted to act upstream of or within folic acid metabolic process. Located in brush border membrane. Is anchored component of plasma membrane. Human ortholog(s) of this gene implicated in cerebral folate receptor alpha deficiency. Orthologous to human FOLR1 (folate receptor alpha); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; endocytosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fbp1; folate binding protein 1; folate receptor 1; folate receptor 1 (adult)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21156,219,460 - 156,238,436 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1156,219,460 - 156,230,667 (-)Ensembl
Rnor_6.01166,934,457 - 166,945,864 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,934,460 - 166,943,592 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,124,242 - 173,135,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,315,191 - 159,324,141 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11159,394,208 - 159,403,158 (-)NCBI
Celera1154,298,870 - 154,310,077 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
5-formyltetrahydrofolic acid  (ISO)
5-methyltetrahydrofolic acid  (ISO)
aldehydo-D-glucose  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid  (ISO)
atrazine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
biochanin A  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
C60 fullerene  (EXP)
chloroethene  (ISO)
ciguatoxin CTX1B  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
diallyl trisulfide  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (EXP,ISO)
flavonoids  (EXP)
flurbiprofen  (ISO)
folic acid  (EXP,ISO)
gallic acid  (ISO)
genistein  (ISO)
glucose  (ISO)
glycidol  (EXP)
hydrogen peroxide  (ISO)
ICI D1694  (ISO)
lead diacetate  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
progesterone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
theophylline  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
urethane  (ISO)
valproic acid  (ISO)
zearalenone  (ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:2527252   PMID:8033114   PMID:10787414   PMID:12477932   PMID:12854656   PMID:14722620   PMID:17286298   PMID:19116913   PMID:19199708   PMID:19581412   PMID:20424322   PMID:21649587  
PMID:23243496   PMID:23376485   PMID:23533145   PMID:23851396   PMID:26667416   PMID:27011008   PMID:30113208  


Genomics

Comparative Map Data
Folr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21156,219,460 - 156,238,436 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1156,219,460 - 156,230,667 (-)Ensembl
Rnor_6.01166,934,457 - 166,945,864 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,934,460 - 166,943,592 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,124,242 - 173,135,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,315,191 - 159,324,141 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11159,394,208 - 159,403,158 (-)NCBI
Celera1154,298,870 - 154,310,077 (-)NCBICelera
Cytogenetic Map1q32NCBI
FOLR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381172,189,709 - 72,196,323 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1172,189,558 - 72,196,323 (+)EnsemblGRCh38hg38GRCh38
GRCh371171,900,753 - 71,907,367 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,578,250 - 71,585,014 (+)NCBINCBI36hg18NCBI36
Build 341171,580,855 - 71,585,014NCBI
Celera1169,202,176 - 69,208,941 (+)NCBI
Cytogenetic Map11q13.4NCBI
HuRef1168,193,609 - 68,200,378 (+)NCBIHuRef
CHM1_11171,784,063 - 71,790,828 (+)NCBICHM1_1
Folr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397101,507,538 - 101,519,995 (-)NCBIGRCm39mm39
GRCm39 Ensembl7101,507,538 - 101,519,995 (-)Ensembl
GRCm387101,858,331 - 101,870,788 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7101,858,331 - 101,870,788 (-)EnsemblGRCm38mm10GRCm38
MGSCv377109,006,845 - 109,019,197 (-)NCBIGRCm37mm9NCBIm37
MGSCv367101,732,152 - 101,744,504 (-)NCBImm8
Celera7102,230,147 - 102,242,481 (-)NCBICelera
Cytogenetic Map7E2NCBI
Folr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541419,187,388 - 19,197,728 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541419,188,830 - 19,197,728 (-)NCBIChiLan1.0ChiLan1.0
FOLR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11170,492,039 - 70,498,665 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1170,492,039 - 70,498,665 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01167,268,721 - 67,275,498 (+)NCBIMhudiblu_PPA_v0panPan3
LOC609612
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12125,944,350 - 25,951,010 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2125,714,017 - 25,720,656 (-)NCBI
ROS_Cfam_1.02126,153,187 - 26,159,847 (-)NCBI
ROS_Cfam_1.0 Ensembl2126,153,297 - 26,159,800 (-)Ensembl
UMICH_Zoey_3.12125,944,449 - 25,951,109 (-)NCBI
UNSW_CanFamBas_1.02126,160,593 - 26,167,256 (-)NCBI
UU_Cfam_GSD_1.02126,062,191 - 26,068,851 (-)NCBI
Folr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494759,892,012 - 59,897,666 (+)NCBI
SpeTri2.0NW_0049364981,489,916 - 1,497,200 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOLR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl96,746,007 - 6,760,433 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.196,753,513 - 6,760,433 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.297,515,002 - 7,521,923 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FOLR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,405,513 - 63,413,372 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl163,406,597 - 63,413,352 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604362,470,494 - 62,476,997 (-)NCBIVero_WHO_p1.0
Folr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248174,830,164 - 4,850,565 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D1Bda29  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21156,220,011 - 156,220,359 (+)MAPPERmRatBN7.2
Rnor_6.01166,935,009 - 166,935,356NCBIRnor6.0
Rnor_5.01173,124,794 - 173,125,141UniSTSRnor5.0
RGSC_v3.41159,315,739 - 159,316,086UniSTSRGSC3.4
Celera1154,299,422 - 154,299,769UniSTS
Cytogenetic Map1q32UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642722214537671Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
2313060Bss71Bone structure and strength QTL 712.60.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1118944747163944747Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121833674166833674Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501168883176Rat
9685799Bp375Blood pressure QTL 375arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
9685802Bp376Blood pressure QTL 376arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1126540680171540680Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
631202Gluco13Glucose level QTL 130.0001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1131763437159756369Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
631206Niddm40Non-insulin dependent diabetes mellitus QTL 40blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1136745990163747690Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383635Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1144267916172949660Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144267916174133260Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
1582204Livw1Liver weight QTL 13.60.0003liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)1155422851172949803Rat
4889419Cstrr2Cold stress response QTL 20.05urine catecholamine amount (VT:0010502)absolute change in urine norepinephrine level (CMO:0001634)1155866514158592016Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:83
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000026962
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 17 14 14 23 35 32
Low 3 14 23 10 19 10 8 11 47 9 11 8
Below cutoff 25 12 12 12 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_133527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006229842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF219904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF219905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF219906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC157811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM059473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM060472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU095827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000026962   ⟹   ENSRNOP00000026962
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1156,219,460 - 156,230,667 (-)Ensembl
Rnor_6.0 Ensembl1166,934,462 - 166,943,592 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079675   ⟹   ENSRNOP00000071311
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1166,934,460 - 166,939,541 (-)Ensembl
RefSeq Acc Id: NM_133527   ⟹   NP_598211
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21156,219,460 - 156,230,667 (-)NCBI
Rnor_6.01166,934,457 - 166,945,845 (-)NCBI
Rnor_5.01173,124,242 - 173,135,651 (-)NCBI
RGSC_v3.41159,315,191 - 159,324,141 (-)RGD
Celera1154,298,870 - 154,310,077 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006229842   ⟹   XP_006229904
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21156,219,574 - 156,227,508 (-)NCBI
Rnor_6.01166,934,457 - 166,942,684 (-)NCBI
Rnor_5.01173,124,242 - 173,135,651 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017588710   ⟹   XP_017444199
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21156,219,464 - 156,229,294 (-)NCBI
Rnor_6.01166,934,457 - 166,944,455 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017588711   ⟹   XP_017444200
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21156,219,464 - 156,229,293 (-)NCBI
Rnor_6.01166,934,457 - 166,945,864 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039085665   ⟹   XP_038941593
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21156,219,460 - 156,238,435 (-)NCBI
RefSeq Acc Id: XM_039085707   ⟹   XP_038941635
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21156,219,574 - 156,238,436 (-)NCBI
RefSeq Acc Id: XM_039085757   ⟹   XP_038941685
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21156,219,464 - 156,238,434 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_598211   ⟸   NM_133527
- Peptide Label: precursor
- UniProtKB: G3V8M6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229904   ⟸   XM_006229842
- Peptide Label: isoform X1
- UniProtKB: G3V8M6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444200   ⟸   XM_017588711
- Peptide Label: isoform X1
- UniProtKB: G3V8M6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444199   ⟸   XM_017588710
- Peptide Label: isoform X1
- UniProtKB: G3V8M6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071311   ⟸   ENSRNOT00000079675
RefSeq Acc Id: ENSRNOP00000026962   ⟸   ENSRNOT00000026962
RefSeq Acc Id: XP_038941593   ⟸   XM_039085665
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038941685   ⟸   XM_039085757
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038941635   ⟸   XM_039085707
- Peptide Label: isoform X1
Protein Domains
Folate_rec

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V8M6-F1-model_v2 AlphaFold G3V8M6 1-255 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690263
Promoter ID:EPDNEW_R786
Type:multiple initiation site
Name:Folr1_1
Description:folate receptor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01166,943,650 - 166,943,710EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 166934576 166934577 T G snv GH/OmrMcwi (MCW), WKY/N (MCW), WKY/NCrl (RGD), SBH/Ygl (MCW), WKY/NCrl (2019), WKY/N (2020), SBH/Ygl (RGD), WKY/NHsd (RGD)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 173124361 173124362 T G snv GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBH/Ygl (KNAW), WKY/N (KNAW), WKY/NCrl (KNAW), ZF (KyushuU), SDLEF7/Barth (UDEL), IS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU), BDIX/NemOda (KyushuU), BDIX.Cg-Tal/NemOda (KyushuU), WKY/NHsd (KNAW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 159315306 159315307 T G snv WKY/N (KNAW), GH/OmrMcwi (MCW), WKY/NHsd (ICL), WKY/NCrl (ICL), SBH/Ygl (ICL)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 156219579 156219580 T G snv WKY/N (2020), WKY/NCrl (2019)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71032 AgrOrtholog
BioCyc Gene G2FUF-58272 BioCyc
Ensembl Genes ENSRNOG00000019902 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000026962 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000071311 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026962 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000079675 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9088301 IMAGE-MGC_LOAD
InterPro Folate_rcpt UniProtKB/TrEMBL
  Folate_rcpt-like UniProtKB/TrEMBL
  FOLR1 UniProtKB/TrEMBL
KEGG Report rno:171049 UniProtKB/TrEMBL
MGC_CLONE MGC:187337 IMAGE-MGC_LOAD
NCBI Gene 171049 ENTREZGENE
PANTHER Folt_rcpt UniProtKB/TrEMBL
  PTHR10517:SF15 UniProtKB/TrEMBL
Pfam Folate_rec UniProtKB/TrEMBL
PhenoGen Folr1 PhenoGen
UniProt A9UMV5_RAT UniProtKB/TrEMBL
  G3V8M6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-05-23 Folr1  folate receptor alpha  Folr1  folate receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-06-29 Folr1  folate receptor 1  Folr1  folate receptor 1 (adult)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Folr1  folate receptor 1 (adult)      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization protein found on the brush borders of kidney tubules 1358236
gene_function reabsorbs folate from the renal tubular fluid 1358236
gene_homology 72-92% homology with Folr1 cDNAs from mouse, human and pig; high amino acid sequence homology among known members of the folate receptor family 70742
gene_regulation the shorter of the two mRNA species in the kidney may be transcribed from a second promoter immediately upstream of exon 3, possibly located within the second intron 70742
gene_regulation protein levels increase in tissue culture cells under conditions of low folate concentration 1358236
gene_regulation in vivo under conditions of low folate concentration, levels of Folr1 protein but not mRNA are decreased in kidney, apparently due to the proteolysis of unsaturated receptor resulting from decreased levels of folate in the glomerular filtrate; levels of protein in liver and brain are essentially unaffected under the same conditions 1358236
gene_transcript kidney expresses two transcripts which differ in the length of their 5' untranslated regions by 311 nucleotides; the mRNA expressed in brain is intermediate in length between the two kidney transcripts 70742
gene_transcript approximately 10 kb in size and has 7 exons and 6 introns 70742