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Gene: Folr1 (folate receptor alpha) Rattus norvegicus
Symbol: Folr1
Name: folate receptor alpha
Description: Exhibits folic acid binding activity. Predicted to be involved in several processes, including circulatory system development; nervous system development; and regulation of signal transduction. Localizes to anchored component of plasma membrane and brush border membrane. Human ortholog(s) of this gene implicated in cerebral folate receptor alpha deficiency. Orthologous to human FOLR1 (folate receptor alpha); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; endocytosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Fbp1; folate binding protein 1; folate receptor 1; folate receptor 1 (adult)
Homo sapiens (human) : FOLR1 (folate receptor alpha)  HGNC  Alliance
Mus musculus (house mouse) : Folr1 (folate receptor 1 (adult))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Folr1 (folate receptor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : FOLR1 (folate receptor alpha)
Canis lupus familiaris (dog) : FOLR1 (folate receptor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Folr1 (folate receptor alpha)
Heterocephalus glaber (naked mole-rat) : Folr1 (folate receptor alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01166,934,457 - 166,945,864 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,934,460 - 166,943,592 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,124,242 - 173,135,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,315,191 - 159,324,141 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11159,394,208 - 159,403,158 (-)NCBI
Celera1154,298,870 - 154,310,077 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Folr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71032
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.