Gene: Spon1 (spondin 1) Rattus norvegicus
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Symbol: Spon1
Name: spondin 1
Description: ENCODES a protein that exhibits LBD domain binding (ortholog); INVOLVED IN negative regulation of amyloid-beta formation (ortholog); positive regulation of amyloid precursor protein catabolic process (ortholog); positive regulation of protein binding (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-colchicine; 17alpha-ethynylestradiol
AGR Description: Predicted to have LBD domain binding activity; predicted to be involved in cell adhesion, positive regulation of protein binding activity, and regulation of protein metabolic process; predicted to localize to the extracellular matrix; orthologous to human SPON1 (spondin 1).
Merged Description: Predicted to have LBD domain binding activity; predicted to be involved in cell adhesion, positive regulation of protein binding activity, and regulation of protein metabolic process; predicted to localize to the extracellular matrix; orthologous to human SPON1 (spondin 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-colchicine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: f-spondin; MGC124557; spondin 1, (f-spondin) extracellular matrix protein; spondin 1, extracellular matrix protein; spondin-1; Sponf
Orthologs:
Homo sapiens (human) : SPON1 (spondin 1)  HGNC  Alliance
Mus musculus (house mouse) : Spon1 (spondin 1, (f-spondin) extracellular matrix protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spon1 (spondin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPON1 (spondin 1)
Canis lupus familiaris (dog) : SPON1 (spondin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spon1 (spondin 1)
Sus scrofa (pig) : SPON1 (spondin 1)
more info ...
Is Marker For: Strains:   SHR.WKY-(D1Got158-D1Got161)/Njs   SHR.WKY-(D1Rat420-D1Got161)/Njs  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01178,568,777 - 178,935,715 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01185,603,907 - 185,902,809 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41171,700,495 - 172,020,808 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11171,822,347 - 172,156,904 (+)NCBI
Celera1165,787,488 - 166,081,019 (+)NCBICelera
Cytogenetic Map1q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Spon1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619918
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.