Arrdc4 (arrestin domain containing 4)

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Gene: Arrdc4 (arrestin domain containing 4) Rattus norvegicus

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Symbol:

Arrdc4

Name:

arrestin domain containing 4

RGD ID:

1311763

Description:

Predicted to have ubiquitin ligase-substrate adaptor activity. Predicted to be involved in several processes, including extracellular vesicle biogenesis; positive regulation of ubiquitin-protein transferase activity; and protein ubiquitination. Predicted to localize to several cellular components, including endosome; extracellular vesicle; and plasma membrane. Orthologous to human ARRDC4 (arrestin domain containing 4); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

Ab1-209; arrestin domain-containing protein 4; liver regeneration-related protein LRRG041/LRRGT00117; LOC293019; LRRG00117

Orthologs:

Homo sapiens (human) : ARRDC4 (arrestin domain containing 4) HGNC Alliance
Mus musculus (house mouse) : Arrdc4 (arrestin domain containing 4) MGI Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arrdc4 (arrestin domain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ARRDC4 (arrestin domain containing 4)
Canis lupus familiaris (dog) : ARRDC4 (arrestin domain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arrdc4 (arrestin domain containing 4)
Sus scrofa (pig) : ARRDC4 (arrestin domain containing 4)
Chlorocebus sabaeus (African green monkey) : ARRDC4 (arrestin domain containing 4)
Heterocephalus glaber (naked mole-rat) : Arrdc4 (arrestin domain containing 4)

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ARRDC4 (arrestin domain containing 4)	HGNC	Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Arrdc4 (arrestin domain containing 4)	HGNC	NCBI, OMA, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Arrdc4 (arrestin domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ARRDC4 (arrestin domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ARRDC4 (arrestin domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Arrdc4 (arrestin domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ARRDC4 (arrestin domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	ARRDC4 (arrestin domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Arrdc4 (arrestin domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ARRDC3 (arrestin domain containing 3)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	ARRDC4 (arrestin domain containing 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Mus musculus (house mouse):	Arrdc4 (arrestin domain containing 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	zgc:110626	Alliance	DIOPT (Ensembl Compara\|OMA)
Drosophila melanogaster (fruit fly):	CG10086	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG1105	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG14696	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Drosophila melanogaster (fruit fly):	CG18746	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG18747	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG18748	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG2993	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	RIM8	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Caenorhabditis elegans (roundworm):	arrd-17	Alliance	DIOPT (OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG18745	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	ROG3	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	Vdup1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	arrd-19	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	arrd-6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	arrd-7	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG2641	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	arrd-13	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	arrd-24	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	arrd-11	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	arrd-18	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	arrd-22	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG18744	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	ALY2	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	ECM21	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	CSR2	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	ALY1	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	LDB19	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	1	129,766,097 - 129,780,076 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	129,766,100 - 129,780,356 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	130,819,069 - 130,833,129 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	123,522,706 - 123,531,698 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	123,602,320 - 123,613,916 (-)	NCBI
Celera	1	114,557,876 - 114,566,923 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

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Model

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Gene-Chemical Interaction Annotations

Gene Ontology Annotations

References - curated

References - uncurated

Genomics

Comparative Map Data

QTLs in Region (Rnor_6.0)

miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences

Protein Sequences

Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Damaging Variants

Additional Information

External Database Links

Nomenclature History

More on Arrdc4
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: rn5 rn6
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	1311763
Created:	2005-01-12
Species:	Rattus norvegicus
Last Modified:	2020-08-20
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)