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Gene: Luzp2 (leucine zipper protein 2) Rattus norvegicus

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Symbol:

Luzp2

Name:

leucine zipper protein 2

RGD ID:

6496163

Description:

Orthologous to human LUZP2 (leucine zipper protein 2); INTERACTS WITH DDT; vinclozolin; zalcitabine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

leucine zipper protein 2-like; LOC100910839; RGD1563838

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LUZP2 (leucine zipper protein 2)	HGNC	NCBI
Mus musculus (house mouse):	Luzp2 (leucine zipper protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Luzp2 (leucine zipper protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LUZP2 (leucine zipper protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LUZP2 (leucine zipper protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Luzp2 (leucine zipper protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LUZP2 (leucine zipper protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LUZP2 (leucine zipper protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Luzp2 (leucine zipper protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	LUZP2 (leucine zipper protein 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Luzp2 (leucine zipper protein 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	luzp2 (leucine zipper protein 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	114,733,026 - 115,119,374 (+)	NCBI		GRCr8
mRatBN7.2	1	105,597,291 - 105,983,605 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	105,597,307 - 105,981,183 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	111,849,494 - 112,067,502 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0	1	113,419,707 - 113,531,330 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	111,849,998 - 113,527,735 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	112,865,072 - 113,075,581 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	1	114,424,838 - 114,538,642 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	1	99,847,765 - 100,234,204 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (ISO)

bisphenol F (ISO)

calcitriol (ISO)

clothianidin (ISO)

daunorubicin (ISO)

DDT (EXP)

ethanol (ISO)

genistein (ISO)

lipopolysaccharide (ISO)

miconazole (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenite (ISO)

testosterone (ISO)

vinclozolin (EXP)

zalcitabine (EXP)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Luzp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	114,733,026 - 115,119,374 (+)	NCBI		GRCr8
mRatBN7.2	1	105,597,291 - 105,983,605 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	105,597,307 - 105,981,183 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	111,849,494 - 112,067,502 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0	1	113,419,707 - 113,531,330 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	111,849,998 - 113,527,735 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	112,865,072 - 113,075,581 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	1	114,424,838 - 114,538,642 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	1	99,847,765 - 100,234,204 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

LUZP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	24,497,053 - 25,082,638 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	24,496,970 - 25,082,638 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	24,518,599 - 25,104,184 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	24,475,132 - 25,060,762 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	24,475,131 - 24,764,817	NCBI
Celera	11	24,655,784 - 25,243,047 (+)	NCBI		Celera
Cytogenetic Map	11	p14.3	NCBI
HuRef	11	24,205,686 - 24,793,425 (+)	NCBI		HuRef
CHM1_1	11	24,517,499 - 25,103,731 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	24,628,114 - 25,216,277 (+)	NCBI		T2T-CHM13v2.0

Luzp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	54,484,936 - 54,918,636 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	54,485,246 - 54,918,633 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	54,835,245 - 55,268,888 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	54,835,498 - 55,268,885 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	62,090,615 - 62,524,258 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	54,703,264 - 55,136,906 (+)	NCBI		MGSCv36	mm8
Celera	7	52,217,308 - 52,619,844 (+)	NCBI		Celera
Cytogenetic Map	7	B5	NCBI
cM Map	7	33.23	NCBI

Luzp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955476	4,440,222 - 4,866,725 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955476	4,440,671 - 4,866,215 (+)	NCBI	ChiLan1.0	ChiLan1.0

LUZP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	26,761,748 - 27,351,470 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	26,760,986 - 27,346,174 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	24,511,185 - 25,100,130 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	24,422,839 - 25,005,593 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	24,423,127 - 25,001,617 (+)	Ensembl	panpan1.1		panPan2

LUZP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	45,926,954 - 46,185,667 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	45,800,989 - 46,185,779 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	45,194,069 - 45,670,040 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	46,840,419 - 47,324,657 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	46,927,710 - 47,323,479 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	45,823,264 - 46,304,005 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	46,005,387 - 46,409,407 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	46,441,543 - 46,992,703 (+)	NCBI		UU_Cfam_GSD_1.0

Luzp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	38,668,127 - 39,143,230 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936540	7,826,746 - 8,297,925 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936540	7,822,913 - 8,298,715 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LUZP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	34,930,423 - 35,464,010 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	34,931,115 - 35,464,174 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	37,567,884 - 37,731,925 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LUZP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	39,914,243 - 40,490,780 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	137,272,615 - 137,765,763 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Luzp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624766	14,949,193 - 15,378,759 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624766	14,948,898 - 15,382,597 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Luzp2
4030 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	125
Count of miRNA genes:	93
Interacting mature miRNAs:	98
Transcripts:	ENSRNOT00000033811, ENSRNOT00000074975
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	78479925	123479925	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	65789093	115540829	Rat
9590300	Scort16	Serum corticosterone level QTL 16	4.39	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	103111621	148111621	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	90532338	123479925	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	78350581	123350581	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
61346	Rf2	Renal disease susceptibility QTL 2	3.7		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	99267916	144267916	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	90664883	143200202	Rat
2317833	Alcrsp19	Alcohol response QTL 19	12.4	0.001	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	100979852	145979852	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
1641897	Alcrsp1	Alcohol response QTL 1			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	100979852	145979852	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	92184926	137184926	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	87580395	150700247	Rat
61370	Mcs3	Mammary carcinoma susceptibility QTL 3	2.15		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	102268556	147268556	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
2303591	Gluco41	Glucose level QTL 41	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	102168504	147168504	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	94494440	117601394	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	66023617	118608521	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
61399	Tcat1	Tongue tumor resistance QTL 1	3.3		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)	1	99267916	144267916	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	77876254	106047988	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	82174743	118944897	Rat
4889494	Scort2	Serum corticosterone level QTL 2	4.2		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	80592172	125592172	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	92948896	144267916	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	77494165	122494165	Rat
8694370	Bw154	Body weight QTL 154	8.91	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	1	103111621	148111621	Rat
1354623	Rf46	Renal function QTL 46	3.8		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	1	102813953	151162766	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)	1	83547917	128547917	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	77857876	122857876	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	78430536	123430536	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat

Markers in Region

D1Got406

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	115,041,949 - 115,042,238 (+)	Marker Load Pipeline
mRatBN7.2	1	105,906,176 - 105,906,465 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	113,446,590 - 113,446,878	NCBI	Rnor6.0
Rnor_5.0	1	114,453,902 - 114,454,190	UniSTS	Rnor5.0
RGSC_v3.4	1	106,290,652 - 106,290,940	UniSTS	RGSC3.4
Celera	1	100,155,829 - 100,156,117	UniSTS
Cytogenetic Map	1		RGD

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
8	7	21	113	58	56	26	18	26	6	138	59	93	38	55	30

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001432773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432774	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432777	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432778	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759471	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039100987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039100988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039100990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039100991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278593	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	FQ213160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214195	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000033811 ⟹ ENSRNOP00000076227

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	105,597,307 - 105,981,183 (+)	Ensembl
Rnor_6.0 Ensembl	1	111,849,998 - 113,527,735 (+)	Ensembl

RefSeq Acc Id:

XM_008759472 ⟹ XP_008757694

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	114,733,096 - 115,119,374 (+)	NCBI
mRatBN7.2	1	105,597,297 - 105,983,605 (+)	NCBI
Rnor_6.0	1	113,419,707 - 113,531,330 (+)	NCBI

Sequence:

show sequence

TCTCTTTCTTTTCCTCAGAATAAAAGTTTGAAAAACAAATTGTTGTCAGGAAGCAAGCTGTGTG
GGATTCATGCAGAAGAGTCCAAAAAAATCCAAGCACAGCTGAAAGAGCTCCGTTACGGGAAGAA
AGACTTGTTATTTAAGGCCCAACAGCTCACTGAACTGGAACAAAAGTTAGCTGTAGCCAAAAAT
GAACTTGAGAAAGCAGCTCTTGACAGGGAATCACAGATGAAAGCAATGAAAGAGACCGTACAAC
TCTGCTTGTCATCAGTTTTCCGTGATCAGCCTCCTCCTTTGAGTCTCTTCCCATCAAATCCAAC
CCAGATGTTACATCCACCCAGGACAATTGCTTCCAGGATTCCAGAAACAAGGACAAAAAGCAAG
CCACAACAAAGTTCTCCAGGACACCATGACAGCTCTCAAGTTCAGGCAACAAAAGAAGAGAGTA
GGAGGACCACTGTGTGTGGCACTCAAGATGAGGGTAGTTCCTGTTTGGCGAAGCATGAGGAGGG
TCCCAAAAGTAACAACACTGCAGAATCAGAGCTCACAACACAGAAATTACAAATGCCTCTTTGT
TCTGAGTGTGAAGAGAAAAAAGTTCCGGAAAAAACATCAGCCAGTTTCGATGGGACTCCAGCTA
GAGAAGAAAAGCTACTGTAATCAGGAGGCATGGGATTCAAAGCTTTCCCGCCATCAATATGTTT
TAGAGTACAGGCTTGATGGGAATACCACGTTTCTAAAGCATGCAACTTTTACAAAACTTTATGT
AACTTTATAATGGGGACTACAAAATTTCCAAAAGATTCCAGGCTGATCGTGAAGCTTAGCAATA
ATCTGATGAAAAGGATTTCTTCACTTACACGTATCTAACTGTCTTCTCTAAAATCACCCAGTAT
AAATTGATCTGTTTTCAACTAAATACAACTGCAACATTTTTTTTGGTCTTTGTGTAGATATCTA
GTACTTCTAAGGTCTAGTTGGTACCTACAACTGGCAGATGATCAACTATGAGTCCTGGTGTTCT
TAAAATCCAAATTGCAAGCATATGAAGGTTTGGTTCACAGTTACCATCTGGTGTCATTTCCCCC
AAATTTGGAATTTGCAGACCAGAATACATTATTTTAGATATTTATTGCTTGGCTCATTACATTG
ACTTAATAACCATTTGATATAAATTGTGCCCAGTTAATTCTGTTAATGATAAATCAGTTACCAG
AGAGCATTAGTTAGTTTTAATATGATATATGCATACAAGGTTTTTCAGTTTTAGAATGAATGAC
AGCTATCTTTCATAGCGTTTTTTGAATTTTAAAACCTTCTTTGTGCATATTCACTGATACTGTT
TCAAGATGTGAATCAAGCTATCTGAAGTGCCAGTTTTATTTCATTCTGCTATTAAGTGATACAA
CGTAAGATGGGAAATTTTCTAAATTATTAACATGCAAGGTGTCCATAGATATTTTAGAATGGAC
ATTTGATTAAAGCAGGATAACATGGAATAATTTTTAAGCAATGTTGTTTTAGCTTTGAAGATAG
GATTTTATATGAGAATATTATCATTTATCAAAAGAACCAGGCTCTGGCATAATTACAGCATAGT
TCCTAATCAAGAACGATAGACAAATAAATTATAACATATGCAACACATCTACTTGGCAGATACA
AACTGACCAATGGATGATGTCAGGGAGTCTACACTCACTGGGTACATTCACTTCTGTTGGTTAA
ACACACTCTGAAAGTACAGGAATAAAAAATAAAACCACTGGCTGTATAGAATTAATATGCTAAG
CCCCAAATAACACCTTTAGAGAACATATCCCAGAATAATAAAAAAGAATTAAAGAATTAGGTCA
GTAGGACTTAATTTCTAGAATCCAATGCCATGTATGTGCTATATGCAAAGAGGTGTATTGAGCT
CTCGAACTGGATAAACTGATGGCAGAGAAAGGAACTCCGCCATGCATTAGTTCTACATGCAAAG
TACTTTTGCGGATTCTATCAGCCTTTCCACTCCTAAAAGAAAAGATAAGGCTGGAAACGACCCA
ACTGTCCCTCAACCGAAGAATGGATGCAGAAAATGTGATTCATTTATACAATGGCATACTATAG
TAAGCCACTGAAAACTAACATTCCTTAACTCCAGTTCAAGGGGGATCTGATGGCCCCTTGTAGC
CTCTGTGGGCATCAAGAATTCACTTAGTGCACAAAAATACATGTGGAAAGAACAGCCGTGTACA
CTTTAATAAATCTGTGGTCAATTTTTTTTAATAAAAGAATTCACGGGGCTGGGGATTTAGCTCA
GTGGTAGAGCGCTTACCTAGGAAGCGCAAGGCCCTGGGTTCGGTCCCCAGCTCCGGAAAAAAGA
ACCAAAAAAATAAATAAATAAATAAATAAAAGAATTCACAGATTTTTATTTAAAAGATGAACTG
ACCAAGATAAAATATAAGATCAGGAGACATGTCCAGTTCCAAATCACTCTACTGCAGTTTCATA
CACTATTAAGTTCTCTTGATAGACTAACACATTTATACTTCTCTATTGCTTTTTCTTTTGAAGC
AAAATCATTCTTTGAAGCAACAAAAACAATGTGTCAAGTTGGGCTCAAAATTAATACAAAGTGG
ATTATGACTTTGACCTGTATATCCTCCTGCCTCTATTCCCCAAGGGCTGAGAGTTTCAGCCTCT
CACGATCACTACAGCAATGAAAACTACTAGTTTGGTTTTAATTTAAGATTGCCTTTCCACTCTT
ATCTCGGCCATTGATTTCCTGCCTCATCCCTGTGGATCCCACAGGATGTTAGCCACTTGACCTT
CCCATGGCACGTTGTGAGTATCTGTGACTCCTCGGTAGGAATGACTGGATAAGGAGTTCCAAGT
TGGAGCAACATTGTTTTCCAGTTTTTTGTTTTGTCTTTGGTTTAACTTCCTGTTCTAGAATGTG
ATAACATAGTCGGTTTTATTCTCTCCCTCTTGGAATGATAAAATGGGTTTTAATCCATAGGGTA
AAATGCCTTCCTAAAATGTATGCATTCTTGTGTATCTACAGGTTTACTCTAGGTTGTGTGTCAT
AATATTTACTCCTATATTTGAAAGAGACACTGTAAGAGCAGGAGGTTTTTTCCTAACCACTTTT
GAGGAACATTACAGAAGTTCATTTAGTAGTTTGATAGCATTGCTTTTAATATGATTTGAGGTTT
TTCTTTAATTAATGTGTTTTTTGTCTCTCCTAGCCTTTTCCTTGCTTTGAAATTGGAATCAAAA
TTTTTAAACTATTTTCCTCACCTGTCTTCTACCCTTCTTAACTACCAACTTTACACTAGATATC
GTTTGAAGAATTAACATGAAGACACTGACCATTCTCACCTGGAAAGAATATTATCCAATATATT
TACAATACATGGTGTGATTCTGTTCTATACTTGCAATGTTAAGTGAAGAATTACAACTTGGAGT
TTACACACTGTCCATTGATGGCTGTTGAGGACTTCCCCATGTTTTCTAATGAAATAACCTATTT
AATATGTCCTTCCACAACAGAGAACAAATTTCTCTATTTTATAATATTATAACAACAACTCAAT
TTAAAGTGTGAATCAAAGACAATGTATTCATTTGTAAATTAGAAAACTTTTGAACTCTGTCTTT
CCTTTTATGTACATAAACTATGTCAATAAACTAGTGCCTCAGACCTGTGAGCCCTAATGAACAC
TGGCTGTGTCTATCGATTAGGTCATGCCCAGAAGAAGATGGTATAAAAATTTCTTCAAACACCT
AAATGTGGAAAATACCAGTGGCTGACTTTGATTTTGTACAGCTTGACTTTGATTTTGAGCAGCT
AATTAGCATAGTATTGCTGTTTCACTCACAGTTTTGTTTCATACAAACACACTGAATTACCAGC
TCAATACAGTTGTGGTTTCGGGGGGGGTGTTTTGTTTTGCTATGTTTTTGTTTGTTTGTTTTGT
ATTTTTTGTTTGTTTTTGAGTTTGTGGAGCAGACGTTTGCTGTTTTAGGTGGACAAGATGTATA
AATGGACTGAAATTAAATTTGTGAATTTGCTGTAACTGGATCCTTTATTTTTATAGCTCAGGTG
TTGCAATTATCACTAACTGCAGCACAGGGAGTGGGAATGGTAATTGGCACCATGGAATAGGGCG
AGTAATGAGCATGATGGTGTTTTTCACATAGGGAACTATACTGGCCAATGCTCTACATGCCTGA
GCTATGTGTTCATCTGGATTATGTCACATGACAGTCAAGTATTGAAAACTAAAAAGTGCTGAAA
GTGGCTTATTTTTCTTGAATAAAGCAATTTGTTACAAAGATCATAATCTATTTTACCTTATGAA
AACTTAATGGACCAGCAAACACTGCCTGCCTCTATAGAGCAGAACCCAAGGACCACCTTGAAAT
CTCATACTGAGAGCTTCTTTATTTGGCAATTCAAATACAGTTAGAGTATTTAAGGAACATAATT
CATGATGGTGGGACATACACTTAATAAATTATTATTAAC

hide sequence

RefSeq Acc Id:

XM_039100987 ⟹ XP_038956915

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	114,733,074 - 115,119,374 (+)	NCBI
mRatBN7.2	1	105,597,302 - 105,983,605 (+)	NCBI

RefSeq Acc Id:

XM_039100988 ⟹ XP_038956916

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	114,733,100 - 115,119,374 (+)	NCBI
mRatBN7.2	1	105,597,298 - 105,983,605 (+)	NCBI

RefSeq Acc Id:

XM_039100990 ⟹ XP_038956918

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	114,733,026 - 114,957,889 (+)	NCBI
mRatBN7.2	1	105,597,291 - 105,823,475 (+)	NCBI

RefSeq Acc Id:

XM_039100991 ⟹ XP_038956919

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	114,733,761 - 115,119,374 (+)	NCBI
mRatBN7.2	1	105,597,948 - 105,983,605 (+)	NCBI

RefSeq Acc Id:

XM_063278593 ⟹ XP_063134663

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	114,733,097 - 115,119,374 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001419702	(Get FASTA)	NCBI Sequence Viewer
	NP_001419703	(Get FASTA)	NCBI Sequence Viewer
	NP_001419704	(Get FASTA)	NCBI Sequence Viewer
	NP_001419705	(Get FASTA)	NCBI Sequence Viewer
	NP_001419706	(Get FASTA)	NCBI Sequence Viewer
	NP_001419707	(Get FASTA)	NCBI Sequence Viewer
	NP_001419708	(Get FASTA)	NCBI Sequence Viewer
	XP_008757694	(Get FASTA)	NCBI Sequence Viewer
	XP_038956915	(Get FASTA)	NCBI Sequence Viewer
	XP_038956916	(Get FASTA)	NCBI Sequence Viewer
	XP_038956918	(Get FASTA)	NCBI Sequence Viewer
	XP_038956919	(Get FASTA)	NCBI Sequence Viewer
	XP_063134663	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000076227.1

RefSeq Acc Id:

XP_008757694 ⟸ XM_008759472

- Peptide Label:

isoform X2

- Sequence:

show sequence

SLSFPQNKSLKNKLLSGSKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTELEQKLAVAKN
ELEKAALDRESQMKAMKETVQLCLSSVFRDQPPPLSLFPSNPTQMLHPPRTIASRIPETRTKSK
PQQSSPGHHDSSQVQATKEESRRTTVCGTQDEGSSCLAKHEEGPKSNNTAESELTTQKLQMPLC
SECEEKKVPEKTSASFDGTPAREEKLL

hide sequence

Ensembl Acc Id:

ENSRNOP00000076227 ⟸ ENSRNOT00000033811

RefSeq Acc Id:	XP_038956918 ⟸ XM_039100990
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038956916 ⟸ XM_039100988
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038956915 ⟸ XM_039100987
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038956919 ⟸ XM_039100991
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_063134663 ⟸ XM_063278593
- Peptide Label:	isoform X4

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A1W2Q6D6-F1-model_v2	AlphaFold	A0A1W2Q6D6	1-345	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:6496163	AgrOrtholog
BioCyc Gene	G2FUF-59488	BioCyc
Ensembl Genes	ENSRNOG00000021507	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000033811.7	UniProtKB/TrEMBL
InterPro	Luzp2	UniProtKB/TrEMBL
NCBI Gene	LOC100910839	ENTREZGENE
PANTHER	LEUCINE ZIPPER PROTEIN 2	UniProtKB/TrEMBL
	PTHR22414	UniProtKB/TrEMBL
PhenoGen	Luzp2	PhenoGen
RatGTEx	ENSRNOG00000021507	RatGTEx
UniProt	A0A1W2Q6D6	ENTREZGENE, UniProtKB/TrEMBL
	A6KD22	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-06-12	Luzp2	leucine zipper protein 2	LOC100910839	leucine zipper protein 2-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-05	LOC100910839	leucine zipper protein 2-like			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar