Gene: Ndn (necdin, MAGE family member) Rattus norvegicus
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Symbol: Ndn
Name: necdin, MAGE family member
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); gamma-tubulin binding (ortholog); RNA polymerase II proximal promoter sequence-specific DNA binding (ortholog); INVOLVED IN axon extension (ortholog); axonal fasciculation (ortholog); axonogenesis (ortholog); ASSOCIATED WITH Angelman syndrome (ortholog); Animal Mammary Neoplasms (ortholog); autism spectrum disorder (ortholog); FOUND IN cytoplasm; cell projection (ortholog); centrosome (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
AGR Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific, RNA polymerase II proximal promoter sequence-specific DNA binding activity, and gamma-tubulin binding activity; predicted to be involved in several processes, including genetic imprinting, multicellular organismal homeostasis, and nervous system development; localizes to the cytoplasm; orthologous to human NDN (necdin, MAGE family member).
Merged Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific, RNA polymerase II proximal promoter sequence-specific DNA binding activity, and gamma-tubulin binding activity; predicted to be involved in several processes, including genetic imprinting, multicellular organismal homeostasis, and nervous system development; localizes to the cytoplasm; orthologous to human NDN (necdin, MAGE family member); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC105768; necdin; necdin homolog; necdin homolog (mouse); necdin, melanoma antigen (MAGE) family member
Orthologs:
Homo sapiens (human) : NDN (necdin, MAGE family member)  HGNC  Alliance
Mus musculus (house mouse) : Ndn (necdin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ndn (necdin, MAGE family member)
Pan paniscus (bonobo/pygmy chimpanzee) : NDN (necdin, MAGE family member)
Canis lupus familiaris (dog) : NDN (necdin, MAGE family member)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ndn (necdin, MAGE family member)
Sus scrofa (pig) : NDN (necdin, MAGE family member)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01122,981,755 - 122,983,354 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01124,119,141 - 124,120,740 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41116,594,603 - 116,596,202 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11116,672,945 - 116,674,545 (+)NCBI
Celera1108,120,324 - 108,121,923 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Ndn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310526
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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