Fcgrt (Fc gamma receptor and transporter) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Fcgrt (Fc gamma receptor and transporter) Rattus norvegicus
Analyze
Symbol: Fcgrt
Name: Fc gamma receptor and transporter
RGD ID: 61811
Description: Enables beta-2-microglobulin binding activity. Predicted to be involved in immune response. Predicted to be located in endosome membrane and plasma membrane. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human FCGRT (Fc gamma receptor and transporter); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fc fragment immunoglobulin G receptor; Fc fragment of IgG receptor and transporter; Fc fragment of IgG, receptor, transporter, alpha; Fc receptor IgG alpha chain transporter; Fc receptor, IgG, alpha chain transporter; FcRn; igG Fc fragment receptor transporter alpha chain; igG receptor FcRn large subunit p51; neonatal Fc receptor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,710,902 - 104,720,685 (-)NCBIGRCr8
mRatBN7.2195,574,436 - 95,584,171 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,567,175 - 95,584,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,959,839 - 100,968,957 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,432,506 - 109,441,624 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,722,909 - 102,732,027 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,086,872 - 101,096,159 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,086,877 - 101,095,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,151,852 - 102,161,703 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,566,717 - 95,575,645 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,644,827 - 95,653,756 (-)NCBI
Celera189,835,561 - 89,844,654 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chlordecone  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
corn oil  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
diethylstilbestrol  (ISO)
diuron  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
hexachlorobenzene  (EXP)
indometacin  (ISO)
lead diacetate  (ISO)
methapyrilene  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulindac sulfide  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. Lebron JA, etal., Cell. 1998 Apr 3;93(1):111-23.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Cloning and expression of the neonatal rat intestinal Fc receptor, a major histocompatibility complex class I antigen homolog. Simister NE and Mostov KE, Cold Spring Harb Symp Quant Biol 1989;54 Pt 1(24):571-80.
10. An Fc receptor structurally related to MHC class I antigens. Simister NE and Mostov KE, Nature 1989 Jan 12;337(6203):184-7.
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
13. Recognition of the tryptophan-based endocytosis signal in the neonatal Fc Receptor by the mu subunit of adaptor protein-2. Wernick NL, etal., J Biol Chem. 2005 Feb 25;280(8):7309-16. doi: 10.1074/jbc.M410752200. Epub 2004 Dec 14.
Additional References at PubMed
PMID:7964511   PMID:7969498   PMID:9493268   PMID:15169676   PMID:15489334   PMID:16382279   PMID:18818657   PMID:19164298   PMID:22573886   PMID:22969064   PMID:23220220   PMID:24802048  
PMID:25658443   PMID:26887834   PMID:33283642  


Genomics

Comparative Map Data
Fcgrt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,710,902 - 104,720,685 (-)NCBIGRCr8
mRatBN7.2195,574,436 - 95,584,171 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,567,175 - 95,584,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,959,839 - 100,968,957 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,432,506 - 109,441,624 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,722,909 - 102,732,027 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,086,872 - 101,096,159 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,086,877 - 101,095,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,151,852 - 102,161,703 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,566,717 - 95,575,645 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,644,827 - 95,653,756 (-)NCBI
Celera189,835,561 - 89,844,654 (-)NCBICelera
Cytogenetic Map1q22NCBI
FCGRT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,512,661 - 49,526,428 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,506,816 - 49,526,428 (+)EnsemblGRCh38hg38GRCh38
GRCh371950,015,918 - 50,029,685 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,708,304 - 54,721,402 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,708,303 - 54,721,400NCBI
Celera1946,884,871 - 46,899,020 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,392,637 - 46,406,719 (+)NCBIHuRef
CHM1_11950,017,336 - 50,031,504 (+)NCBICHM1_1
T2T-CHM13v2.01952,512,666 - 52,526,423 (+)NCBIT2T-CHM13v2.0
Fcgrt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,742,417 - 44,753,246 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,742,414 - 44,753,275 (-)EnsemblGRCm39 Ensembl
GRCm38745,092,993 - 45,103,822 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,092,990 - 45,103,851 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,348,363 - 52,359,192 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,961,106 - 44,971,134 (-)NCBIMGSCv36mm8
Celera740,545,146 - 40,556,581 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.12NCBI
Fcgrt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,318,967 - 1,332,141 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,320,441 - 1,331,962 (-)NCBIChiLan1.0ChiLan1.0
FCGRT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,628,042 - 55,642,176 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,548,687 - 57,562,540 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,525,053 - 46,539,136 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,442,760 - 55,459,904 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,442,760 - 55,459,904 (+)Ensemblpanpan1.1panPan2
FCGRT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11106,982,833 - 106,991,574 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1106,982,833 - 106,991,467 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,566,112 - 106,574,862 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,502,839 - 107,511,637 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,502,844 - 107,511,442 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,175,946 - 107,184,686 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,818,118 - 106,826,848 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,659,085 - 107,667,872 (-)NCBIUU_Cfam_GSD_1.0
Fcgrt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,749,833 - 21,762,855 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,368,031 - 3,381,045 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,368,063 - 3,381,039 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCGRT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,581,133 - 54,599,783 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,581,103 - 54,599,193 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,310,155 - 50,328,168 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FCGRT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,693,531 - 42,704,686 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,694,344 - 42,704,472 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,625,346 - 22,640,812 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fcgrt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248324,709,083 - 4,719,152 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,710,024 - 4,718,997 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fcgrt
33 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:46
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000027944
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)194494440117601394Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)15034351099980958Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat

Markers in Region
BQ211283  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01102,156,730 - 102,156,885UniSTSRnor5.0
RH 3.4 Map1908.4UniSTS
Cytogenetic Map1q22UniSTS
D37874  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,574,546 - 95,574,642 (+)MAPPERmRatBN7.2
Rnor_6.01101,086,983 - 101,087,078NCBIRnor6.0
Rnor_5.01102,151,963 - 102,152,058UniSTSRnor5.0
RGSC_v3.4195,566,823 - 95,566,918UniSTSRGSC3.4
Celera189,835,667 - 89,835,762UniSTS
Cytogenetic Map1q22UniSTS
D1Bda16  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,574,516 - 95,574,771 (+)MAPPERmRatBN7.2
Rnor_6.01101,086,953 - 101,087,207NCBIRnor6.0
Rnor_5.01102,151,933 - 102,152,187UniSTSRnor5.0
RGSC_v3.4195,566,793 - 95,567,047UniSTSRGSC3.4
Celera189,835,637 - 89,835,891UniSTS
Cytogenetic Map1q22UniSTS
RH141669  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,581,972 - 95,582,172 (+)MAPPERmRatBN7.2
Rnor_6.01101,094,007 - 101,094,206NCBIRnor6.0
Rnor_5.01102,159,552 - 102,159,751UniSTSRnor5.0
RGSC_v3.4195,574,058 - 95,574,257UniSTSRGSC3.4
Celera189,843,067 - 89,843,266UniSTS
RH 3.4 Map1908.09UniSTS
Cytogenetic Map1q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000027944   ⟹   ENSRNOP00000027944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,567,175 - 95,584,084 (-)Ensembl
Rnor_6.0 Ensembl1101,086,877 - 101,095,594 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099731   ⟹   ENSRNOP00000093291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,574,442 - 95,584,084 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104770   ⟹   ENSRNOP00000093469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,574,434 - 95,584,073 (-)Ensembl
RefSeq Acc Id: NM_033351   ⟹   NP_203502
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,710,907 - 104,720,026 (-)NCBI
mRatBN7.2195,574,441 - 95,583,560 (-)NCBI
Rnor_6.01101,086,877 - 101,095,594 (-)NCBI
Rnor_5.01102,151,852 - 102,161,703 (-)NCBI
RGSC_v3.4195,566,717 - 95,575,645 (-)RGD
Celera189,835,561 - 89,844,654 (-)RGD
Sequence:
RefSeq Acc Id: XM_006229043   ⟹   XP_006229105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,710,902 - 104,720,685 (-)NCBI
mRatBN7.2195,574,436 - 95,584,171 (-)NCBI
Rnor_6.01101,086,872 - 101,096,159 (-)NCBI
Rnor_5.01102,151,852 - 102,161,703 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589060   ⟹   XP_017444549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,710,902 - 104,720,614 (-)NCBI
mRatBN7.2195,574,436 - 95,584,148 (-)NCBI
Rnor_6.01101,086,872 - 101,096,159 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109565   ⟹   XP_038965493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,710,902 - 104,720,530 (-)NCBI
mRatBN7.2195,574,436 - 95,583,991 (-)NCBI
RefSeq Acc Id: XM_039109580   ⟹   XP_038965508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,710,902 - 104,720,637 (-)NCBI
mRatBN7.2195,574,436 - 95,584,171 (-)NCBI
RefSeq Acc Id: XM_063287635   ⟹   XP_063143705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,710,902 - 104,720,527 (-)NCBI
RefSeq Acc Id: NP_203502   ⟸   NM_033351
- Peptide Label: precursor
- UniProtKB: P13599 (UniProtKB/Swiss-Prot),   A6JAW9 (UniProtKB/TrEMBL),   A0A8L2QEY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229105   ⟸   XM_006229043
- Peptide Label: isoform X1
- UniProtKB: P13599 (UniProtKB/Swiss-Prot),   A6JAW9 (UniProtKB/TrEMBL),   A0A8L2QEY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444549   ⟸   XM_017589060
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QEY2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027944   ⟸   ENSRNOT00000027944
RefSeq Acc Id: XP_038965508   ⟸   XM_039109580
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GKP0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965493   ⟸   XM_039109565
- Peptide Label: isoform X1
- UniProtKB: P13599 (UniProtKB/Swiss-Prot),   A6JAW9 (UniProtKB/TrEMBL),   A0A8L2QEY2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000093469   ⟸   ENSRNOT00000104770
Ensembl Acc Id: ENSRNOP00000093291   ⟸   ENSRNOT00000099731
RefSeq Acc Id: XP_063143705   ⟸   XM_063287635
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GKP0 (UniProtKB/TrEMBL)
Protein Domains
Ig-like   Ig-like C1-type   Immunoglobulin C1-set

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P13599-F1-model_v2 AlphaFold P13599 1-366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690023
Promoter ID:EPDNEW_R548
Type:single initiation site
Name:Fcgrt_1
Description:Fc fragment of IgG receptor and transporter
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01101,095,534 - 101,095,594EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61811 AgrOrtholog
BioCyc Gene G2FUF-59728 BioCyc
Ensembl Genes ENSRNOG00000020583 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055005666 UniProtKB/Swiss-Prot
  ENSRNOG00060008172 UniProtKB/Swiss-Prot
  ENSRNOG00065028717 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027944.7 UniProtKB/TrEMBL
  ENSRNOT00000099731.1 UniProtKB/TrEMBL
  ENSRNOT00000104770.1 UniProtKB/TrEMBL
  ENSRNOT00055009126 UniProtKB/Swiss-Prot
  ENSRNOT00060013550 UniProtKB/Swiss-Prot
  ENSRNOT00065049602 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5623787 IMAGE-MGC_LOAD
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_class-I_related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I_a_a1/a2 UniProtKB/TrEMBL
KEGG Report rno:29558 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72370 IMAGE-MGC_LOAD
NCBI Gene 29558 ENTREZGENE
PANTHER IGG RECEPTOR FCRN LARGE SUBUNIT P51 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC CLASS I-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fcgrt PhenoGen
PRINTS MHCCLASSI UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_MHC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020583 RatGTEx
  ENSRNOG00055005666 RatGTEx
  ENSRNOG00060008172 RatGTEx
  ENSRNOG00065028717 RatGTEx
SMART IGc1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC204786
UniProt A0A8I6AFJ8_RAT UniProtKB/TrEMBL
  A0A8I6GKP0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QEY2 ENTREZGENE, UniProtKB/TrEMBL
  A6JAW9 ENTREZGENE, UniProtKB/TrEMBL
  FCGRN_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-11-18 Fcgrt  Fc gamma receptor and transporter  Fcgrt  Fc fragment of IgG receptor and transporter  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-20 Fcgrt  Fc fragment of IgG receptor and transporter  Fcgrt  Fc fragment of IgG, receptor, transporter, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Fcgrt  Fc fragment of IgG, receptor, transporter, alpha  Fcgrt  Fc receptor, IgG, alpha chain transporter  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Fcgrt  Fc receptor, IgG, alpha chain transporter      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference