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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61811
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fcgrt
Name: Fc gamma receptor and transporter
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fcgrtdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of FCGRT mRNAPMID:30816183 PMID:34947998
Fcgrtincreases expressionEXP 6480464CTDbisphenol A results in increased expression of FCGRT mRNA; bisphenol A results in increased expression of FCGRT proteinPMID:24552547 PMID:25181051
Fcgrtaffects expressionISOFCGRT (Homo sapiens)6480464CTDbisphenol A affects the expression of FCGRT mRNAPMID:30903817
Fcgrtdecreases methylationISOFCGRT (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of FCGRT genePMID:31601247
Fcgrtincreases expressionISOFcgrt (Mus musculus)6480464CTDbisphenol A results in increased expression of FCGRT mRNAPMID:30951980 PMID:34585602
Fcgrtmultiple interactionsISOFCGRT (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FCGRT mRNAPMID:28628672
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