Fcgrt (Fc gamma receptor and transporter)

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Gene: Fcgrt (Fc gamma receptor and transporter) Ictidomys tridecemlineatus

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Symbol:

Fcgrt

Name:

Fc gamma receptor and transporter (Ensembl:Fc fragment of IgG receptor and transporter)

RGD ID:

12694949

Description:

ENCODES a protein that exhibits beta-2-microglobulin binding (ortholog); peptide antigen binding (ortholog); INVOLVED IN immune response (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 12 (ortholog); FOUND IN endosome membrane (inferred); external side of plasma membrane (inferred); extracellular space (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Fc fragment of IgG receptor and transporter; IgG receptor FcRn large subunit p51

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,749,833 - 21,762,855 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	3,368,031 - 3,381,045 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	3,368,063 - 3,381,039 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy 12 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

immune response (IEA)

Cellular Component

endosome membrane (IEA)

external side of plasma membrane (IEA)

extracellular space (IEA)

membrane (IEA)

Molecular Function

beta-2-microglobulin binding (IEA,ISO)

IgG binding (IEA)

peptide antigen binding (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Fcgrt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,749,833 - 21,762,855 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	3,368,031 - 3,381,045 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	3,368,063 - 3,381,039 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FCGRT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	49,512,661 - 49,526,428 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	49,506,816 - 49,526,428 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	50,015,918 - 50,029,685 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	54,708,304 - 54,721,402 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	54,708,303 - 54,721,400	NCBI
Celera	19	46,884,871 - 46,899,020 (+)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	46,392,637 - 46,406,719 (+)	NCBI		HuRef
CHM1_1	19	50,017,336 - 50,031,504 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	52,512,666 - 52,526,423 (+)	NCBI		T2T-CHM13v2.0

Fcgrt
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,742,417 - 44,753,246 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,742,414 - 44,753,275 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	45,092,993 - 45,103,822 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	45,092,990 - 45,103,851 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,348,363 - 52,359,192 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	44,961,106 - 44,971,134 (-)	NCBI		MGSCv36	mm8
Celera	7	40,545,146 - 40,556,581 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	29.12	NCBI

Fcgrt
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,710,902 - 104,720,685 (-)	NCBI		GRCr8
mRatBN7.2	1	95,574,436 - 95,584,171 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,567,175 - 95,584,084 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,959,839 - 100,968,957 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	109,432,506 - 109,441,624 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,722,909 - 102,732,027 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	101,086,872 - 101,096,159 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	101,086,877 - 101,095,594 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	102,151,852 - 102,161,703 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,566,717 - 95,575,645 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	95,644,827 - 95,653,756 (-)	NCBI
Celera	1	89,835,561 - 89,844,654 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Fcgrt
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,318,967 - 1,332,141 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,320,441 - 1,331,962 (-)	NCBI	ChiLan1.0	ChiLan1.0

FCGRT
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	55,628,042 - 55,642,176 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	57,548,687 - 57,562,540 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	46,525,053 - 46,539,136 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	55,442,760 - 55,459,904 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,442,760 - 55,459,904 (+)	Ensembl	panpan1.1		panPan2

FCGRT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,982,833 - 106,991,574 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	106,982,833 - 106,991,467 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	106,566,112 - 106,574,862 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	107,502,839 - 107,511,637 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	107,502,844 - 107,511,442 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	107,175,946 - 107,184,686 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	106,818,118 - 106,826,848 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	107,659,085 - 107,667,872 (-)	NCBI		UU_Cfam_GSD_1.0

FCGRT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	54,581,133 - 54,599,783 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	54,581,103 - 54,599,193 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	50,310,155 - 50,328,168 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FCGRT
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	42,693,531 - 42,704,686 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	42,694,344 - 42,704,472 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	22,625,346 - 22,640,812 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fcgrt
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,709,083 - 4,719,152 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	4,710,024 - 4,718,997 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005336679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013363534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040279613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040279614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000014625 ⟹ ENSSTOP00000013102

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936664	3,368,031 - 3,381,045 (+)	Ensembl

RefSeq Acc Id:

XM_005336679 ⟹ XP_005336736

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409349	21,749,833 - 21,762,855 (+)	NCBI
SpeTri2.0	NW_004936664	3,368,063 - 3,381,039 (+)	NCBI

Sequence:

show sequence

TTGGATCTTCTGGGAGTCAGGGAGCCAGCTCCGGACAGGATGTGAGAGAGGAACTGGGGTCTCC
AGTCACGGGAGGCAGCCAGAACTGCAGGCAGGAAGAGAACCAGGCGGCAGTCGCCCTCTCAGCA
TGGGGGTGCCCTGGCCTCAGCCCTGGGCACTCGGTCTCCTGCTCTTCCTCCTTCCTCAGACCCG
GGGTGCAGAGAATCATCTGTCCCTGCTGTACCACCTCACGGCTGTGTCCTCCCCGGCCCCGGGG
ACTCCCGCCTTCTGGGTGTCAGGTTGGCTGGGCCCCCAGCAGTACCTGAGCTACAGCAGCCTGA
GGGCTGAGGCTGAGCCCTGTGGGGCTTGGGTCTGGGAAAACCAGGTGTCGTGGTATTGGGAGAA
GGAGACCACAGACCTGAGAAACAAGGAGAAGCTCTTTCTGGACGCTCTCGCAGCCCTGGGGAGA
AAAGGATCCTACACCCTGCAGGGCCTGTTGGGTTGTGAACTAGGCCCTGACAACGTTTCGGTGC
CTACCGCCACGTTTGCCCTGAATGGTGAGGAATTCATGAGGTTCGACCCCAAGAACGGGAACTG
GACTGGGGACTGGCCAGAGGCCCAGACCATCAGTGAGAAGTGGATGCAGCAAGCTGAGGCGGTC
GGGAAGGAGAGGACGTTCCTGCTCAACTCCTGCCCCCAGCGGCTGCTGGGACACCTAGAGAGGG
GCCGTGTAAACCTCGAGTGGAAGGAGCCACCATCCATGCGCTTGAAGGCCCGGCCCAGCAGCCC
TGGCTTTTCCGTGCTCACCTGCAGTGCCTTCTCCTTCTACCCTCCGGAGCTGCAGCTTAGGTTC
CTGAGGAATGGGCTGGCAGCTGGCTCTGGAGAGGGCGGCTTTGGTCCCAATGGGGATGGCTCCT
TCCATGCCTGGTCATCACTCATCGTCAAAAGTGGCGATGAGCATCACTACTGCTGCATTGTGCA
GCATGCGGGGCTGGCACAGCCCCTCACCGTGGAACTGGAGTCGCCAGCCAAGTCCTCGGTGCCT
GTGGTCGGAATCATCATTGGCTTCTTGCTGCTCACGGCAGTGGCTGCAGGAGGAGCTCTGCTGT
GGAGGAGGATGAGGAATGGGCTGCCAGCCCCTTGGATCTCTTTCCGTGGGGACGACGTGGGAGC
CCTCCTGCCCACTCCAGGCCTGCCCGAGGATGCGGACTGTCAAGATATAAATTCATTCCCAGCA
ACTGCTTGAC

hide sequence

RefSeq Acc Id:

XM_040279613 ⟹ XP_040135547

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409349	21,749,833 - 21,762,855 (+)	NCBI

RefSeq Acc Id:

XM_040279614 ⟹ XP_040135548

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409349	21,749,862 - 21,762,855 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005336736	(Get FASTA)	NCBI Sequence Viewer
	XP_040135547	(Get FASTA)	NCBI Sequence Viewer
	XP_040135548	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000013102.3
GenBank Protein	KAG3256511	(Get FASTA)	NCBI Sequence Viewer
	KAG3256512	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005336736 ⟸ XM_005336679
- Peptide Label:	isoform X2
- UniProtKB:	I3MN99 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGVPWPQPWALGLLLFLLPQTRGAENHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYSSL RAEAEPCGAWVWENQVSWYWEKETTDLRNKEKLFLDALAALGRKGSYTLQGLLGCELGPDNVSV PTATFALNGEEFMRFDPKNGNWTGDWPEAQTISEKWMQQAEAVGKERTFLLNSCPQRLLGHLER GRVNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGSGEGGFGPNGDGS FHAWSSLIVKSGDEHHYCCIVQHAGLAQPLTVELESPAKSSVPVVGIIIGFLLLTAVAAGGALL WRRMRNGLPAPWISFRGDDVGALLPTPGLPEDADCQDINSFPATA hide sequence

RefSeq Acc Id:	XP_040135547 ⟸ XM_040279613
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_040135548 ⟸ XM_040279614
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSSTOP00000013102 ⟸ ENSSTOT00000014625

Protein Domains

Ig-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000014628	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000014625.3	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
	3.30.500.10	UniProtKB/TrEMBL
InterPro	Ig-like_dom	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig/MHC_CS	UniProtKB/TrEMBL
	Ig_C1-set	UniProtKB/TrEMBL
	MHC_class-I_related	UniProtKB/TrEMBL
	MHC_I-like_Ag-recog	UniProtKB/TrEMBL
	MHC_I-like_Ag-recog_sf	UniProtKB/TrEMBL
	MHC_I/II-like_Ag-recog	UniProtKB/TrEMBL
NCBI Gene	Fcgrt	ENTREZGENE
PANTHER	IGG RECEPTOR FCRN LARGE SUBUNIT P51	UniProtKB/TrEMBL
	MHC CLASS I-RELATED	UniProtKB/TrEMBL
Pfam	C1-set	UniProtKB/TrEMBL
	MHC_I	UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/TrEMBL
	IG_MHC	UniProtKB/TrEMBL
SMART	IGc1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
	SSF54452	UniProtKB/TrEMBL
UniProt	I3MN99	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-11-16	Fcgrt	Fc gamma receptor and transporter	Fcgrt	Fc fragment of IgG receptor and transporter	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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