FCGRT (Fc gamma receptor and transporter) - Rat Genome Database

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Gene: FCGRT (Fc gamma receptor and transporter) Homo sapiens
Analyze
Symbol: FCGRT
Name: Fc gamma receptor and transporter
RGD ID: 736100
HGNC Page HGNC:3621
Description: Enables IgG binding activity. Predicted to be involved in immune response. Predicted to be located in endosome membrane and plasma membrane. Predicted to be active in external side of plasma membrane and extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: alpha-chain; Fc fragment of IgG receptor and transporter; Fc fragment of IgG, receptor, transporter, alpha; fc receptor, igg, alpha chain transporter; FcgammaRn; FCRN; FcRn alpha chain; heavy chain of the major histocompatibility complex class I-like Fc receptor; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; neonatal Fc receptor; neonatal Fc-receptor for Ig; neonatal fragment crystallizable Fc receptor FcRn; transmembrane alpha chain of the neonatal receptor
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,512,661 - 49,526,428 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,506,816 - 49,526,428 (+)EnsemblGRCh38hg38GRCh38
GRCh371950,015,918 - 50,029,685 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,708,304 - 54,721,402 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,708,303 - 54,721,400NCBI
Celera1946,884,871 - 46,899,020 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,392,637 - 46,406,719 (+)NCBIHuRef
CHM1_11950,017,336 - 50,031,504 (+)NCBICHM1_1
T2T-CHM13v2.01952,512,666 - 52,526,423 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrotoluene  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
aflatoxin B1  (EXP)
Aflatoxin B2 alpha  (EXP)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (EXP)
beta-lapachone  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
chlordecone  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP)
copper(II) sulfate  (EXP)
corn oil  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP)
dexamethasone  (EXP,ISO)
Dibutyl phosphate  (EXP)
diethylstilbestrol  (ISO)
diuron  (EXP)
elemental selenium  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
fipronil  (ISO)
flutamide  (ISO)
folic acid  (ISO)
hexachlorobenzene  (ISO)
indometacin  (EXP)
lead diacetate  (ISO)
methapyrilene  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
selenium atom  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
Soman  (ISO)
sulindac sulfide  (EXP)
temozolomide  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (EXP)
vinclozolin  (ISO)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7964511   PMID:8145026   PMID:8646894   PMID:8871627   PMID:9439449   PMID:9493268   PMID:10933786   PMID:10998088   PMID:11207281   PMID:11717196   PMID:12006623   PMID:12023961  
PMID:12144784   PMID:12477932   PMID:12538789   PMID:12566415   PMID:12885906   PMID:12972260   PMID:14630397   PMID:14764666   PMID:14767057   PMID:15258288   PMID:15340161   PMID:15489334  
PMID:15644205   PMID:15654966   PMID:15689494   PMID:16229888   PMID:16303743   PMID:16549777   PMID:16805790   PMID:16849638   PMID:17046328   PMID:17048273   PMID:17346028   PMID:17384151  
PMID:17674040   PMID:17703228   PMID:17709515   PMID:18003977   PMID:18566411   PMID:18599440   PMID:18637944   PMID:18684948   PMID:18843053   PMID:19164298   PMID:19275696   PMID:19362735  
PMID:19423540   PMID:19451275   PMID:19462839   PMID:19772792   PMID:20006594   PMID:20018855   PMID:20083659   PMID:20139978   PMID:20406964   PMID:20438785   PMID:20452034   PMID:20592032  
PMID:20627700   PMID:20639872   PMID:20930418   PMID:21256596   PMID:21368166   PMID:21690327   PMID:21873635   PMID:22199357   PMID:22204844   PMID:22215085   PMID:22453095   PMID:22570488  
PMID:23022100   PMID:23220220   PMID:23286945   PMID:23384837   PMID:23741050   PMID:23751752   PMID:23765230   PMID:23917469   PMID:24057047   PMID:24072267   PMID:24278022   PMID:24469444  
PMID:24550358   PMID:24652290   PMID:24764301   PMID:24802048   PMID:25030041   PMID:25344603   PMID:25652137   PMID:25658443   PMID:25823782   PMID:26186194   PMID:26252948   PMID:26254986  
PMID:26260795   PMID:26337808   PMID:26634928   PMID:27016466   PMID:27469170   PMID:27836572   PMID:27974681   PMID:28081504   PMID:28450240   PMID:28514442   PMID:28637874   PMID:28760885  
PMID:28991504   PMID:28991911   PMID:29302759   PMID:29523681   PMID:29540212   PMID:29745444   PMID:29782488   PMID:29908223   PMID:30326650   PMID:30808762   PMID:30893823   PMID:30955709  
PMID:31089170   PMID:31209240   PMID:31289263   PMID:31536960   PMID:32296183   PMID:32461366   PMID:32658257   PMID:33025844   PMID:33077645   PMID:33360096   PMID:33961781   PMID:34079125  
PMID:34373451   PMID:34634960   PMID:34704415   PMID:34753797   PMID:34996950   PMID:35862785   PMID:36607699   PMID:36726033   PMID:38205888   PMID:38353127   PMID:38607033   PMID:38971109  


Genomics

Comparative Map Data
FCGRT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,512,661 - 49,526,428 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,506,816 - 49,526,428 (+)EnsemblGRCh38hg38GRCh38
GRCh371950,015,918 - 50,029,685 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,708,304 - 54,721,402 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,708,303 - 54,721,400NCBI
Celera1946,884,871 - 46,899,020 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,392,637 - 46,406,719 (+)NCBIHuRef
CHM1_11950,017,336 - 50,031,504 (+)NCBICHM1_1
T2T-CHM13v2.01952,512,666 - 52,526,423 (+)NCBIT2T-CHM13v2.0
Fcgrt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,742,417 - 44,753,246 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,742,414 - 44,753,275 (-)EnsemblGRCm39 Ensembl
GRCm38745,092,993 - 45,103,822 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,092,990 - 45,103,851 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,348,363 - 52,359,192 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,961,106 - 44,971,134 (-)NCBIMGSCv36mm8
Celera740,545,146 - 40,556,581 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.12NCBI
Fcgrt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,710,902 - 104,720,685 (-)NCBIGRCr8
mRatBN7.2195,574,436 - 95,584,171 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,567,175 - 95,584,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,959,839 - 100,968,957 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,432,506 - 109,441,624 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,722,909 - 102,732,027 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,086,872 - 101,096,159 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,086,877 - 101,095,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,151,852 - 102,161,703 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,566,717 - 95,575,645 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,644,827 - 95,653,756 (-)NCBI
Celera189,835,561 - 89,844,654 (-)NCBICelera
Cytogenetic Map1q22NCBI
Fcgrt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,318,967 - 1,332,141 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,320,441 - 1,331,962 (-)NCBIChiLan1.0ChiLan1.0
FCGRT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,628,042 - 55,642,176 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,548,687 - 57,562,540 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,525,053 - 46,539,136 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,442,760 - 55,459,904 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,442,760 - 55,459,904 (+)Ensemblpanpan1.1panPan2
FCGRT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11106,982,833 - 106,991,574 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1106,982,833 - 106,991,467 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,566,112 - 106,574,862 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,502,839 - 107,511,637 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,502,844 - 107,511,442 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,175,946 - 107,184,686 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,818,118 - 106,826,848 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,659,085 - 107,667,872 (-)NCBIUU_Cfam_GSD_1.0
Fcgrt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,749,833 - 21,762,855 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,368,031 - 3,381,045 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,368,063 - 3,381,039 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCGRT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,581,133 - 54,599,783 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,581,103 - 54,599,193 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,310,155 - 50,328,168 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FCGRT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,693,531 - 42,704,686 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,694,344 - 42,704,472 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,625,346 - 22,640,812 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fcgrt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248324,709,083 - 4,719,152 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,710,024 - 4,718,997 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FCGRT
36 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43
pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic|uncertain significance
NM_001136019.3(FCGRT):c.1048G>A (p.Ala350Thr) single nucleotide variant not specified [RCV004306462] Chr19:49526069 [GRCh38]
Chr19:50029326 [GRCh37]
Chr19:19q13.33
uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
NM_001136019.3(FCGRT):c.396G>C (p.Lys132Asn) single nucleotide variant not provided [RCV000951155] Chr19:49514281 [GRCh38]
Chr19:49514281..49514282 [GRCh38]
Chr19:50017538 [GRCh37]
Chr19:50017538..50017539 [GRCh37]
Chr19:19q13.33
benign
NM_001136019.3(FCGRT):c.1020C>T (p.Thr340=) single nucleotide variant not provided [RCV000965455] Chr19:49526041 [GRCh38]
Chr19:50029298 [GRCh37]
Chr19:19q13.33
benign
GRCh37/hg19 19q13.33(chr19:49600909-51366070)x3 copy number gain not provided [RCV000847250] Chr19:49600909..51366070 [GRCh37]
Chr19:19q13.33
uncertain significance
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3 copy number gain not provided [RCV001007050] Chr19:44738088..53621561 [GRCh37]
Chr19:19q13.31-13.42
pathogenic
NM_001136019.3(FCGRT):c.126G>T (p.Pro42=) single nucleotide variant not provided [RCV000969323] Chr19:49513934 [GRCh38]
Chr19:50017191 [GRCh37]
Chr19:19q13.33
benign
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871) copy number gain not provided [RCV001249294] Chr19:47939842..54626871 [GRCh37]
Chr19:19q13.32-13.42
not provided
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3 copy number gain not provided [RCV001259944] Chr19:48463931..57095254 [GRCh37]
Chr19:19q13.33-13.43
pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:49911081-53127438) copy number gain not specified [RCV002052689] Chr19:49911081..53127438 [GRCh37]
Chr19:19q13.33-13.41
likely pathogenic
NC_000019.9:g.(?_49519325)_(50366015_?)dup duplication Developmental and epileptic encephalopathy, 12 [RCV002030046] Chr19:49519325..50366015 [GRCh37]
Chr19:19q13.33
uncertain significance
NC_000019.9:g.(?_48618906)_(50921204_?)dup duplication Developmental and epileptic encephalopathy, 12 [RCV001939968]|not provided [RCV001916178] Chr19:48618906..50921204 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.608C>A (p.Pro203His) single nucleotide variant not specified [RCV004316438] Chr19:49524513 [GRCh38]
Chr19:50027770 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.748G>A (p.Gly250Ser) single nucleotide variant not specified [RCV004106796] Chr19:49524653 [GRCh38]
Chr19:50027910 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.810G>C (p.Glu270Asp) single nucleotide variant not specified [RCV004144593] Chr19:49524715 [GRCh38]
Chr19:50027972 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.986C>G (p.Pro329Arg) single nucleotide variant not specified [RCV004206738] Chr19:49525571 [GRCh38]
Chr19:50028828 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.589C>A (p.Leu197Met) single nucleotide variant not specified [RCV004118240] Chr19:49514474 [GRCh38]
Chr19:50017731 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.916G>A (p.Gly306Ser) single nucleotide variant not specified [RCV004219868] Chr19:49525501 [GRCh38]
Chr19:50028758 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.516C>A (p.Asn172Lys) single nucleotide variant not specified [RCV004125533] Chr19:49514401 [GRCh38]
Chr19:50017658 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.1016A>C (p.Asp339Ala) single nucleotide variant not specified [RCV004137328] Chr19:49526037 [GRCh38]
Chr19:50029294 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.52C>T (p.Leu18Phe) single nucleotide variant not specified [RCV004221979] Chr19:49513452 [GRCh38]
Chr19:50016709 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.577G>T (p.Gly193Cys) single nucleotide variant not specified [RCV004248594] Chr19:49514462 [GRCh38]
Chr19:50017719 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.733G>A (p.Gly245Ser) single nucleotide variant not specified [RCV004258074] Chr19:49524638 [GRCh38]
Chr19:50027895 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.151G>A (p.Gly51Ser) single nucleotide variant not specified [RCV004269334] Chr19:49513959 [GRCh38]
Chr19:50017216 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.548C>G (p.Pro183Arg) single nucleotide variant not specified [RCV004321052] Chr19:49514433 [GRCh38]
Chr19:50017690 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.1046A>G (p.Glu349Gly) single nucleotide variant not specified [RCV004310375] Chr19:49526067 [GRCh38]
Chr19:50029324 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.881C>G (p.Ala294Gly) single nucleotide variant not specified [RCV004346922] Chr19:49525466 [GRCh38]
Chr19:50028723 [GRCh37]
Chr19:19q13.33
uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3 copy number gain not provided [RCV003485200] Chr19:49625130..57647352 [GRCh37]
Chr19:19q13.33-13.43
likely pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:48905537-51614930)x3 copy number gain not specified [RCV003986127] Chr19:48905537..51614930 [GRCh37]
Chr19:19q13.33-13.41
likely pathogenic
NM_001136019.3(FCGRT):c.1007G>A (p.Arg336His) single nucleotide variant not specified [RCV004391434] Chr19:49526028 [GRCh38]
Chr19:50029285 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.316G>C (p.Gly106Arg) single nucleotide variant not specified [RCV004391438] Chr19:49514124 [GRCh38]
Chr19:50017381 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.920T>C (p.Val307Ala) single nucleotide variant not specified [RCV004391442] Chr19:49525505 [GRCh38]
Chr19:50028762 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.193C>G (p.Arg65Gly) single nucleotide variant not specified [RCV004391437] Chr19:49514001 [GRCh38]
Chr19:50017258 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.332A>G (p.Tyr111Cys) single nucleotide variant not specified [RCV004391439] Chr19:49514217 [GRCh38]
Chr19:50017474 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.611C>G (p.Ser204Cys) single nucleotide variant not specified [RCV004391440] Chr19:49524516 [GRCh38]
Chr19:50027773 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.125C>T (p.Pro42Leu) single nucleotide variant not specified [RCV004391435] Chr19:49513933 [GRCh38]
Chr19:50017190 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.17C>G (p.Pro6Arg) single nucleotide variant not specified [RCV004391436] Chr19:49513417 [GRCh38]
Chr19:50016674 [GRCh37]
Chr19:19q13.33
uncertain significance
NC_000019.9:g.(?_49713446)_(50413064_?)dup duplication Developmental and epileptic encephalopathy, 12 [RCV004581120] Chr19:49713446..50413064 [GRCh37]
Chr19:19q13.33
uncertain significance
NM_001136019.3(FCGRT):c.847G>A (p.Ala283Thr) single nucleotide variant not specified [RCV004618478] Chr19:49524752 [GRCh38]
Chr19:50028009 [GRCh37]
Chr19:19q13.33
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:6854
Count of miRNA genes:1060
Interacting mature miRNAs:1343
Transcripts:ENST00000221466, ENST00000426395, ENST00000452439, ENST00000593381, ENST00000593431, ENST00000594823, ENST00000595677, ENST00000595881, ENST00000596147, ENST00000596975, ENST00000598076, ENST00000598319, ENST00000598491, ENST00000598927, ENST00000598936, ENST00000598949, ENST00000599701, ENST00000599988, ENST00000600273
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407308487GWAS957463_Hglycoprotein measurement QTL GWAS957463 (human)2e-31glycoprotein measurement194951349149513492Human
406993091GWAS642067_Hsex hormone-binding globulin measurement QTL GWAS642067 (human)8e-36sex hormone-binding globulin measurement194951322249513223Human
407345859GWAS994835_Htotal cholesterol measurement QTL GWAS994835 (human)4e-41total cholesterol measurementblood total cholesterol level (CMO:0000051)194951350249513503Human
407313729GWAS962705_Htestosterone measurement QTL GWAS962705 (human)2e-12testosterone measurementserum testosterone level (CMO:0000568)194951322249513223Human
407325902GWAS974878_Htriglyceride measurement QTL GWAS974878 (human)2e-08triglyceride measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)194951349149513492Human
407074250GWAS723226_Homega-6 polyunsaturated fatty acid measurement QTL GWAS723226 (human)9e-11omega-6 polyunsaturated fatty acid measurement194951350249513503Human
407039176GWAS688152_Hglycoprotein measurement QTL GWAS688152 (human)4e-18glycoprotein measurement194951349149513492Human
407345484GWAS994460_Htotal cholesterol measurement QTL GWAS994460 (human)2e-11total cholesterol measurementblood total cholesterol level (CMO:0000051)194951350249513503Human
407202248GWAS851224_Hserum albumin measurement QTL GWAS851224 (human)6e-176serum albumin measurementserum albumin level (CMO:0000550)194951428149514282Human
406956623GWAS605599_Hhemoglobin measurement QTL GWAS605599 (human)4e-13hemoglobin measurementhemoglobin measurement (CMO:0000508)194952300949523010Human
407066963GWAS715939_Hblood protein measurement QTL GWAS715939 (human)9e-113blood protein measurementblood protein measurement (CMO:0000028)194951428149514282Human
407184343GWAS833319_Hvery low density lipoprotein cholesterol measurement QTL GWAS833319 (human)5e-08very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)194951349149513492Human
407253460GWAS902436_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS902436 (human)3e-08triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194951350249513503Human
407066967GWAS715943_Hblood protein measurement QTL GWAS715943 (human)1e-61blood protein measurementblood protein measurement (CMO:0000028)194951968249519683Human
407202512GWAS851488_Hcalcium measurement QTL GWAS851488 (human)2e-53calcium measurementblood calcium level (CMO:0000502)194951428149514282Human
406903385GWAS552361_Htriglyceride measurement QTL GWAS552361 (human)0.0000002triglyceride measurementblood triglyceride level (CMO:0000118)194951350249513503Human
407128157GWAS777133_Hphospholipids in small LDL measurement QTL GWAS777133 (human)1e-12phospholipids in small LDL measurement 194951350249513503Human
406931160GWAS580136_Htotal cholesterol measurement QTL GWAS580136 (human)3e-13total cholesterol measurementblood total cholesterol level (CMO:0000051)194951350249513503Human
407185759GWAS834735_Htriglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS834735 (human)6e-09linoleic acid measurementblood free fatty acids level (CMO:0000117)194951349149513492Human
407180889GWAS829865_Htotal cholesterol measurement QTL GWAS829865 (human)4e-11total cholesterol measurementblood total cholesterol level (CMO:0000051)194951350249513503Human
407232091GWAS881067_Hhemoglobin measurement QTL GWAS881067 (human)4e-13hemoglobin measurementhemoglobin measurement (CMO:0000508)194951428149514282Human
407321816GWAS970792_Htotal cholesterol measurement QTL GWAS970792 (human)3e-26total cholesterol measurementblood total cholesterol level (CMO:0000051)194951350249513503Human
407184608GWAS833584_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS833584 (human)3e-08very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)194951349149513492Human
407279971GWAS928947_Htriglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS928947 (human)9e-10triglyceride measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)194951349149513492Human
406913511GWAS562487_Htriglyceride measurement QTL GWAS562487 (human)2e-09omega-6 polyunsaturated fatty acid measurementblood triglyceride level (CMO:0000118)194951349149513492Human
407340129GWAS989105_Hhemoglobin measurement QTL GWAS989105 (human)3e-19hemoglobin measurementhemoglobin measurement (CMO:0000508)194951350249513503Human
407172450GWAS821426_Hserum albumin measurement QTL GWAS821426 (human)8e-58serum albumin measurementserum albumin level (CMO:0000550)194951968249519683Human
406913510GWAS562486_Htriglyceride measurement QTL GWAS562486 (human)8e-09triglyceride measurementblood triglyceride level (CMO:0000118)194951349149513492Human
407087978GWAS736954_Hlinoleic acid measurement QTL GWAS736954 (human)2e-10milk polyunsaturated fatty acid amount (VT:0010374)blood high density lipoprotein cholesterol level (CMO:0000052)194951350249513503Human
407313132GWAS962108_Hserum non-albumin protein measurement QTL GWAS962108 (human)2e-18serum non-albumin protein measurementserum globulin level (CMO:0002399)194951428149514282Human
407062892GWAS711868_Hglycoprotein measurement QTL GWAS711868 (human)2e-18glycoprotein measurement194951322249513223Human
407027570GWAS676546_Htestosterone measurement QTL GWAS676546 (human)3e-16testosterone measurementserum testosterone level (CMO:0000568)194951371449513715Human
407170548GWAS819524_Halkaline phosphatase measurement QTL GWAS819524 (human)8e-10alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)194952195149521952Human
407069299GWAS718275_Htotal blood protein measurement QTL GWAS718275 (human)1e-86total blood protein measurementblood protein measurement (CMO:0000028)194952300949523010Human
406993648GWAS642624_Hsex hormone-binding globulin measurement QTL GWAS642624 (human)5e-16sex hormone-binding globulin measurement194951349149513492Human
407237495GWAS886471_Haspartate aminotransferase measurement QTL GWAS886471 (human)7e-14aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)194951350249513503Human
407155836GWAS804812_Hlow density lipoprotein cholesterol measurement QTL GWAS804812 (human)4e-12low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194951350249513503Human
406993656GWAS642632_Hsex hormone-binding globulin measurement QTL GWAS642632 (human)2e-10fatty acid measurement194951349149513492Human
407122431GWAS771407_Hreticulocyte count QTL GWAS771407 (human)4e-10reticulocyte counttotal reticulocyte count (CMO:0003020)194951322249513223Human
407196409GWAS845385_Hsex hormone-binding globulin measurement QTL GWAS845385 (human)3e-10triglyceride measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)194951349149513492Human
407268218GWAS917194_Hsex hormone-binding globulin measurement QTL GWAS917194 (human)4e-10sex hormone-binding globulin measurement194951349149513492Human
407071871GWAS720847_Hserum albumin measurement QTL GWAS720847 (human)2e-17non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)194951350249513503Human
407009279GWAS658255_Htestosterone measurement QTL GWAS658255 (human)2e-20testosterone measurementserum testosterone level (CMO:0000568)194951371449513715Human
407003133GWAS652109_Hsex hormone-binding globulin measurement QTL GWAS652109 (human)2e-46sex hormone-binding globulin measurement194951322249513223Human
407185402GWAS834378_Hcalcium measurement QTL GWAS834378 (human)2e-38calcium measurementblood calcium level (CMO:0000502)194951428149514282Human
407309831GWAS958807_Hpolyunsaturated fatty acid measurement QTL GWAS958807 (human)5e-10milk polyunsaturated fatty acid amount (VT:0010374)milk polyunsaturated fatty acid measurement (CMO:0000821)194951349149513492Human
407214087GWAS863063_Halkaline phosphatase measurement QTL GWAS863063 (human)5e-15alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)194951428149514282Human
407183110GWAS832086_Hcalcium measurement QTL GWAS832086 (human)2e-19calcium measurementblood calcium level (CMO:0000502)194951968249519683Human
407256578GWAS905554_Hfatty acid measurement QTL GWAS905554 (human)3e-11fatty acid measurement194951349149513492Human
406912261GWAS561237_Hserum gamma-glutamyl transferase measurement QTL GWAS561237 (human)8e-09serum gamma-glutamyl transferase measurementserum gamma-glutamyltransferase activity level (CMO:0002241)194951350249513503Human
406911621GWAS560597_Hhematocrit QTL GWAS560597 (human)6e-13hematocrithematocrit (CMO:0000037)194951350249513503Human
407121025GWAS770001_Hphospholipids:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS770001 (human)4e-10phospholipids:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)194951350249513503Human
407314048GWAS963024_Hlow density lipoprotein cholesterol measurement QTL GWAS963024 (human)2e-19low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194951350249513503Human
407201676GWAS850652_Herythrocyte count QTL GWAS850652 (human)9e-16erythrocyte countred blood cell count (CMO:0000025)194951428149514282Human
406958856GWAS607832_Herythrocyte count QTL GWAS607832 (human)6e-11erythrocyte countred blood cell count (CMO:0000025)194952300949523010Human
406979336GWAS628312_Hhemoglobin measurement QTL GWAS628312 (human)5e-14hemoglobin measurementhemoglobin measurement (CMO:0000508)194951428149514282Human
407112458GWAS761434_Herythrocyte count QTL GWAS761434 (human)6e-13erythrocyte countred blood cell count (CMO:0000025)194951428149514282Human
407318280GWAS967256_Hsex hormone-binding globulin measurement QTL GWAS967256 (human)5e-12sex hormone-binding globulin measurement194951322249513223Human
407244681GWAS893657_Hsex hormone-binding globulin measurement QTL GWAS893657 (human)0.000005sex hormone-binding globulin measurement194951349149513492Human
407333768GWAS982744_Hnon-high density lipoprotein cholesterol measurement QTL GWAS982744 (human)9e-25non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)194951350249513503Human
407313160GWAS962136_Hserum non-albumin protein measurement QTL GWAS962136 (human)2e-12serum non-albumin protein measurementserum globulin level (CMO:0002399)194951968249519683Human
407022994GWAS671970_Hsex hormone-binding globulin measurement QTL GWAS671970 (human)6e-32sex hormone-binding globulin measurement194951322249513223Human
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human
407326867GWAS975843_Hlow density lipoprotein cholesterol measurement QTL GWAS975843 (human)1e-15low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194951350249513503Human
407322770GWAS971746_Hlow density lipoprotein cholesterol measurement QTL GWAS971746 (human)2e-12low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194951350249513503Human
407322769GWAS971745_Hlow density lipoprotein cholesterol measurement QTL GWAS971745 (human)8e-11low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194951349149513492Human
406937879GWAS586855_Hserum albumin measurement QTL GWAS586855 (human)3e-81serum albumin measurementserum albumin level (CMO:0000550)194951350249513503Human
406987413GWAS636389_Hsex hormone-binding globulin measurement QTL GWAS636389 (human)8e-33sex hormone-binding globulin measurement194951322249513223Human
407254417GWAS903393_Hhigh density lipoprotein cholesterol measurement QTL GWAS903393 (human)1e-09high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)194952113449521135Human
407176093GWAS825069_Hserum albumin measurement QTL GWAS825069 (human)6e-119serum albumin measurementserum albumin level (CMO:0000550)194951428149514282Human
407121816GWAS770792_Hesterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS770792 (human)1e-09triglyceride measurementblood triglyceride level (CMO:0000118)194951350249513503Human
406992030GWAS641006_Hlevel of IgG receptor FcRn large subunit p51 in blood serum QTL GWAS641006 (human)2e-20level of IgG receptor FcRn large subunit p51 in blood serum194952478349524784Human
1331657COPD9_HChronic obstructive pulmonary disease QTL 9 (human)1.94Chronic airflow obstructionpost-bronchodilator FEV1193102176057021760Human
406916641GWAS565617_Htriglyceride measurement QTL GWAS565617 (human)3e-16triglyceride measurementblood triglyceride level (CMO:0000118)194951350249513503Human
406932384GWAS581360_Hapolipoprotein B measurement QTL GWAS581360 (human)3e-10apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)194951350249513503Human
406980387GWAS629363_Hhematocrit QTL GWAS629363 (human)1e-15hematocrithematocrit (CMO:0000037)194951428149514282Human
407006757GWAS655733_Hsex hormone-binding globulin measurement QTL GWAS655733 (human)2e-37sex hormone-binding globulin measurement194951322249513223Human
407055018GWAS703994_Htotal blood protein measurement QTL GWAS703994 (human)2e-152total blood protein measurementblood protein measurement (CMO:0000028)194951428149514282Human
407188527GWAS837503_Haspartate aminotransferase to alanine aminotransferase ratio QTL GWAS837503 (human)6e-12aspartate aminotransferase to alanine aminotransferase ratioserum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio (CMO:0002245)194951428149514282Human
407306924GWAS955900_Htype 2 diabetes mellitus QTL GWAS955900 (human)2e-08type 2 diabetes mellitus194951350249513503Human
407167785GWAS816761_Hcalcium measurement QTL GWAS816761 (human)3e-08calcium measurementblood calcium level (CMO:0000502)194952461549524616Human
407345192GWAS994168_Hcalcium measurement QTL GWAS994168 (human)6e-37calcium measurementblood calcium level (CMO:0000502)194951428149514282Human
407068215GWAS717191_Hblood protein measurement QTL GWAS717191 (human)6e-11blood protein measurementblood protein measurement (CMO:0000028)194952437849524379Human
407327420GWAS976396_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS976396 (human)1e-08triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194951349149513492Human
407081144GWAS730120_Htotal blood protein measurement QTL GWAS730120 (human)4e-171total blood protein measurementblood protein measurement (CMO:0000028)194951350249513503Human
406900028GWAS549004_Htriglyceride measurement QTL GWAS549004 (human)8e-19triglyceride measurementblood triglyceride level (CMO:0000118)194951350249513503Human
407238713GWAS887689_Hserum albumin measurement QTL GWAS887689 (human)1e-56serum albumin measurementserum albumin level (CMO:0000550)194951350249513503Human
407027006GWAS675982_Hsex hormone-binding globulin measurement QTL GWAS675982 (human)5e-10sex hormone-binding globulin measurement194951371449513715Human

Markers in Region
RH103715  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371950,028,339 - 50,028,467UniSTSGRCh37
Build 361954,720,151 - 54,720,279RGDNCBI36
Celera1946,897,674 - 46,897,802RGD
Cytogenetic Map19q13.3UniSTS
HuRef1946,405,373 - 46,405,501UniSTS
GeneMap99-GB4 RH Map19269.13UniSTS
SHGC-12954  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371950,029,386 - 50,029,587UniSTSGRCh37
Build 361954,721,198 - 54,721,399RGDNCBI36
Celera1946,898,721 - 46,898,922RGD
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map19q13.33UniSTS
HuRef1946,406,420 - 46,406,621UniSTS
TNG Radiation Hybrid Map1918289.0UniSTS
GeneMap99-G3 RH Map192530.0UniSTS
FCGRT_2894  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371950,029,164 - 50,029,739UniSTSGRCh37
Build 361954,720,976 - 54,721,551RGDNCBI36
Celera1946,898,499 - 46,899,074RGD
HuRef1946,406,198 - 46,406,773UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2437 2788 2252 4969 1726 2349 6 624 1942 465 2265 7295 6463 52 3734 1 849 1744 1615 174 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001136019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_004107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC010619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF220542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF453513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF453514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF453515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF453516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF453517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH009974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK074734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC091487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE245284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI520292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT006828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX647163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC312637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF064735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY503191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY503192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY503193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY503194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  PQ136863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  PQ136864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  PQ136865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  PQ136866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  PQ136867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U12255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000221466   ⟹   ENSP00000221466
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,512,661 - 49,526,428 (+)Ensembl
Ensembl Acc Id: ENST00000426395   ⟹   ENSP00000410798
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,154 - 49,526,333 (+)Ensembl
Ensembl Acc Id: ENST00000452439
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,395 - 49,525,164 (+)Ensembl
Ensembl Acc Id: ENST00000593381   ⟹   ENSP00000472256
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,918 - 49,524,644 (+)Ensembl
Ensembl Acc Id: ENST00000593431
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,398 - 49,525,012 (+)Ensembl
Ensembl Acc Id: ENST00000594823
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,197 - 49,524,664 (+)Ensembl
Ensembl Acc Id: ENST00000595677
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,177 - 49,521,813 (+)Ensembl
Ensembl Acc Id: ENST00000595881
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,195 - 49,526,331 (+)Ensembl
Ensembl Acc Id: ENST00000596147
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,506,816 - 49,524,780 (+)Ensembl
Ensembl Acc Id: ENST00000596975   ⟹   ENSP00000471118
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,379 - 49,526,329 (+)Ensembl
Ensembl Acc Id: ENST00000598076   ⟹   ENSP00000471232
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,514,058 - 49,526,333 (+)Ensembl
Ensembl Acc Id: ENST00000598319   ⟹   ENSP00000472604
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,404 - 49,525,263 (+)Ensembl
Ensembl Acc Id: ENST00000598491   ⟹   ENSP00000472350
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,512,375 - 49,514,309 (+)Ensembl
Ensembl Acc Id: ENST00000598927   ⟹   ENSP00000469968
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,512,662 - 49,526,297 (+)Ensembl
Ensembl Acc Id: ENST00000598936
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,390 - 49,524,568 (+)Ensembl
Ensembl Acc Id: ENST00000599701   ⟹   ENSP00000472794
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,512,635 - 49,514,421 (+)Ensembl
Ensembl Acc Id: ENST00000599988   ⟹   ENSP00000471300
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,255 - 49,526,333 (+)Ensembl
Ensembl Acc Id: ENST00000600273   ⟹   ENSP00000469933
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,513,179 - 49,514,388 (+)Ensembl
RefSeq Acc Id: NM_001136019   ⟹   NP_001129491
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,512,661 - 49,526,428 (+)NCBI
GRCh371950,015,536 - 50,029,685 (+)NCBI
HuRef1946,392,637 - 46,406,719 (+)ENTREZGENE
CHM1_11950,017,336 - 50,031,504 (+)NCBI
T2T-CHM13v2.01952,512,666 - 52,526,423 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001411064   ⟹   NP_001397993
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,513,266 - 49,526,333 (+)NCBI
T2T-CHM13v2.01952,513,271 - 52,526,328 (+)NCBI
RefSeq Acc Id: NM_004107   ⟹   NP_004098
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,513,266 - 49,526,428 (+)NCBI
GRCh371950,015,536 - 50,029,685 (+)ENTREZGENE
GRCh371950,015,536 - 50,029,685 (+)NCBI
Build 361954,708,304 - 54,721,402 (+)NCBI Archive
HuRef1946,392,637 - 46,406,719 (+)ENTREZGENE
CHM1_11950,018,236 - 50,031,504 (+)NCBI
T2T-CHM13v2.01952,513,271 - 52,526,423 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047438408   ⟹   XP_047294364
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,512,661 - 49,524,776 (+)NCBI
RefSeq Acc Id: XM_047438410   ⟹   XP_047294366
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,512,661 - 49,524,776 (+)NCBI
RefSeq Acc Id: XM_047438411   ⟹   XP_047294367
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,512,661 - 49,526,428 (+)NCBI
RefSeq Acc Id: XM_047438412   ⟹   XP_047294368
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,512,661 - 49,521,773 (+)NCBI
RefSeq Acc Id: XM_054320199   ⟹   XP_054176174
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,513,163 - 52,526,423 (+)NCBI
RefSeq Acc Id: XM_054320200   ⟹   XP_054176175
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,512,666 - 52,524,777 (+)NCBI
RefSeq Acc Id: XM_054320201   ⟹   XP_054176176
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,512,666 - 52,524,777 (+)NCBI
RefSeq Acc Id: XM_054320202   ⟹   XP_054176177
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,512,666 - 52,526,423 (+)NCBI
RefSeq Acc Id: XM_054320203   ⟹   XP_054176178
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,512,666 - 52,521,775 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001129491 (Get FASTA)   NCBI Sequence Viewer  
  NP_001397993 (Get FASTA)   NCBI Sequence Viewer  
  NP_004098 (Get FASTA)   NCBI Sequence Viewer  
  XP_047294364 (Get FASTA)   NCBI Sequence Viewer  
  XP_047294366 (Get FASTA)   NCBI Sequence Viewer  
  XP_047294367 (Get FASTA)   NCBI Sequence Viewer  
  XP_047294368 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176174 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176175 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176176 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176177 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176178 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA58958 (Get FASTA)   NCBI Sequence Viewer  
  AAF72596 (Get FASTA)   NCBI Sequence Viewer  
  AAG31421 (Get FASTA)   NCBI Sequence Viewer  
  AAH08734 (Get FASTA)   NCBI Sequence Viewer  
  AAM27922 (Get FASTA)   NCBI Sequence Viewer  
  AAM27923 (Get FASTA)   NCBI Sequence Viewer  
  AAM27924 (Get FASTA)   NCBI Sequence Viewer  
  AAM27925 (Get FASTA)   NCBI Sequence Viewer  
  AAM27926 (Get FASTA)   NCBI Sequence Viewer  
  AAP35474 (Get FASTA)   NCBI Sequence Viewer  
  ABK41918 (Get FASTA)   NCBI Sequence Viewer  
  ARO48560 (Get FASTA)   NCBI Sequence Viewer  
  ARO48561 (Get FASTA)   NCBI Sequence Viewer  
  ARO48562 (Get FASTA)   NCBI Sequence Viewer  
  ARO48563 (Get FASTA)   NCBI Sequence Viewer  
  BAG52159 (Get FASTA)   NCBI Sequence Viewer  
  BAG52164 (Get FASTA)   NCBI Sequence Viewer  
  BAH12955 (Get FASTA)   NCBI Sequence Viewer  
  CAI46032 (Get FASTA)   NCBI Sequence Viewer  
  EAW52498 (Get FASTA)   NCBI Sequence Viewer  
  EAW52499 (Get FASTA)   NCBI Sequence Viewer  
  EAW52500 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000221466
  ENSP00000221466.4
  ENSP00000410798
  ENSP00000410798.2
  ENSP00000469933
  ENSP00000469933.1
  ENSP00000469968.1
  ENSP00000471118
  ENSP00000471118.1
  ENSP00000471232.1
  ENSP00000471300.1
  ENSP00000472256.1
  ENSP00000472350.1
  ENSP00000472604.1
  ENSP00000472794.1
GenBank Protein P55899 (Get FASTA)   NCBI Sequence Viewer  
  XDQ84328 (Get FASTA)   NCBI Sequence Viewer  
  XDQ84329 (Get FASTA)   NCBI Sequence Viewer  
  XDQ84330 (Get FASTA)   NCBI Sequence Viewer  
  XDQ84331 (Get FASTA)   NCBI Sequence Viewer  
  XDQ84332 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001129491   ⟸   NM_001136019
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9HBV7 (UniProtKB/Swiss-Prot),   Q5HYM5 (UniProtKB/Swiss-Prot),   Q9NZ19 (UniProtKB/Swiss-Prot),   P55899 (UniProtKB/Swiss-Prot),   A0A024QZI2 (UniProtKB/TrEMBL),   A0A1W6R2Y2 (UniProtKB/TrEMBL),   A0A1W6R2Z1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_004098   ⟸   NM_004107
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9HBV7 (UniProtKB/Swiss-Prot),   Q5HYM5 (UniProtKB/Swiss-Prot),   Q9NZ19 (UniProtKB/Swiss-Prot),   P55899 (UniProtKB/Swiss-Prot),   A0A024QZI2 (UniProtKB/TrEMBL),   A0A1W6R2Y2 (UniProtKB/TrEMBL),   A0A1W6R2Z1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000471118   ⟸   ENST00000596975
Ensembl Acc Id: ENSP00000410798   ⟸   ENST00000426395
Ensembl Acc Id: ENSP00000469968   ⟸   ENST00000598927
Ensembl Acc Id: ENSP00000471232   ⟸   ENST00000598076
Ensembl Acc Id: ENSP00000472350   ⟸   ENST00000598491
Ensembl Acc Id: ENSP00000472604   ⟸   ENST00000598319
Ensembl Acc Id: ENSP00000471300   ⟸   ENST00000599988
Ensembl Acc Id: ENSP00000472794   ⟸   ENST00000599701
Ensembl Acc Id: ENSP00000469933   ⟸   ENST00000600273
Ensembl Acc Id: ENSP00000221466   ⟸   ENST00000221466
Ensembl Acc Id: ENSP00000472256   ⟸   ENST00000593381
RefSeq Acc Id: XP_047294367   ⟸   XM_047438411
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047294364   ⟸   XM_047438408
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047294366   ⟸   XM_047438410
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047294368   ⟸   XM_047438412
- Peptide Label: isoform X4
RefSeq Acc Id: NP_001397993   ⟸   NM_001411064
- Peptide Label: isoform 2 precursor
- UniProtKB: M0R0A9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054176177   ⟸   XM_054320202
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054176175   ⟸   XM_054320200
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054176176   ⟸   XM_054320201
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054176178   ⟸   XM_054320203
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054176174   ⟸   XM_054320199
- Peptide Label: isoform X5
- UniProtKB: Q9HBV7 (UniProtKB/Swiss-Prot),   Q5HYM5 (UniProtKB/Swiss-Prot),   P55899 (UniProtKB/Swiss-Prot),   Q9NZ19 (UniProtKB/Swiss-Prot),   A0A024QZI2 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P55899-F1-model_v2 AlphaFold P55899 1-365 view protein structure

Promoters
RGD ID:13205151
Promoter ID:EPDNEW_H26155
Type:initiation region
Name:FCGRT_2
Description:Fc fragment of IgG receptor and transporter
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26156  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,512,313 - 49,512,373EPDNEW
RGD ID:13205149
Promoter ID:EPDNEW_H26156
Type:initiation region
Name:FCGRT_1
Description:Fc fragment of IgG receptor and transporter
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26155  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,513,220 - 49,513,280EPDNEW
RGD ID:6795174
Promoter ID:HG_KWN:30548
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:NM_001136019,   NM_004107,   UC002POD.1,   UC002POF.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361954,708,166 - 54,708,666 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:3621 AgrOrtholog
COSMIC FCGRT COSMIC
Ensembl Genes ENSG00000104870 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000221466 ENTREZGENE
  ENST00000221466.10 UniProtKB/Swiss-Prot
  ENST00000426395 ENTREZGENE
  ENST00000426395.7 UniProtKB/Swiss-Prot
  ENST00000593381.5 UniProtKB/TrEMBL
  ENST00000596975 ENTREZGENE
  ENST00000596975.5 UniProtKB/TrEMBL
  ENST00000598076.1 UniProtKB/TrEMBL
  ENST00000598319.5 UniProtKB/TrEMBL
  ENST00000598491.5 UniProtKB/TrEMBL
  ENST00000598927.5 UniProtKB/TrEMBL
  ENST00000599701.5 UniProtKB/TrEMBL
  ENST00000599988.5 UniProtKB/TrEMBL
  ENST00000600273 ENTREZGENE
  ENST00000600273.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000104870 GTEx
HGNC ID HGNC:3621 ENTREZGENE
Human Proteome Map FCGRT Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_class-I_related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:2217 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 2217 ENTREZGENE
OMIM 601437 OMIM
PANTHER IGG RECEPTOR FCRN LARGE SUBUNIT P51 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC CLASS I-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA28067 PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_MHC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024QZI2 ENTREZGENE, UniProtKB/TrEMBL
  A0A1W6R2Y2 ENTREZGENE, UniProtKB/TrEMBL
  A0A1W6R2Z1 ENTREZGENE, UniProtKB/TrEMBL
  FCGRN_HUMAN UniProtKB/Swiss-Prot
  M0QYM4_HUMAN UniProtKB/TrEMBL
  M0QYN1_HUMAN UniProtKB/TrEMBL
  M0QYN9_HUMAN UniProtKB/TrEMBL
  M0R0A9 ENTREZGENE, UniProtKB/TrEMBL
  M0R0H0_HUMAN UniProtKB/TrEMBL
  M0R0K7_HUMAN UniProtKB/TrEMBL
  M0R220_HUMAN UniProtKB/TrEMBL
  M0R266_HUMAN UniProtKB/TrEMBL
  M0R2T3_HUMAN UniProtKB/TrEMBL
  P55899 ENTREZGENE
  Q5HYM5 ENTREZGENE
  Q9HBV7 ENTREZGENE
  Q9NZ19 ENTREZGENE
UniProt Secondary Q5HYM5 UniProtKB/Swiss-Prot
  Q9HBV7 UniProtKB/Swiss-Prot
  Q9NZ19 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-11-15 FCGRT  Fc gamma receptor and transporter  FCGRT  Fc fragment of IgG receptor and transporter  Symbol and/or name change 19259463 PROVISIONAL
2016-01-19 FCGRT  Fc fragment of IgG receptor and transporter  FCGRT  Fc fragment of IgG, receptor, transporter, alpha  Symbol and/or name change 5135510 APPROVED