Gene: Ap2m1 (adaptor related protein complex 2 subunit mu 1) Rattus norvegicus
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Symbol: Ap2m1
Name: adaptor related protein complex 2 subunit mu 1
Description: ENCODES a protein that exhibits cargo receptor activity; low-density lipoprotein particle receptor binding; signal sequence binding; INVOLVED IN positive regulation of receptor internalization; positive regulation of synaptic vesicle endocytosis; postsynaptic neurotransmitter receptor internalization; PARTICIPATES IN Arf family mediated signaling pathway; clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; ASSOCIATED WITH Currarino Triad (ortholog); FOUND IN AP-2 adaptor complex; glutamatergic synapse; plasma membrane (ortholog); INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; amiodarone
AGR Description: Exhibits cargo receptor activity, low-density lipoprotein particle receptor binding activity, and signal sequence binding activity; involved in endocytosis, positive regulation of endocytosis, and protein-containing complex assembly; localizes to the AP-2 adaptor complex and glutamatergic synapse; orthologous to human AP2M1 (adaptor related protein complex 2 subunit mu 1).
Merged Description: Exhibits cargo receptor activity, low-density lipoprotein particle receptor binding activity, and signal sequence binding activity; involved in endocytosis, positive regulation of endocytosis, and protein-containing complex assembly; localizes to the AP-2 adaptor complex and glutamatergic synapse; orthologous to human AP2M1 (adaptor related protein complex 2 subunit mu 1); PARTICIPATES IN Arf family mediated signaling pathway; clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; amiodarone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adapter-related protein complex 2 mu subunit; adapter-related protein complex 2 subunit mu; adaptor protein complex AP-2 subunit mu; adaptor-related protein complex 2 subunit mu; adaptor-related protein complex 2, mu 1 subunit; AP-2 complex subunit mu; AP-2 mu chain; Ap50; Clapm1; clathrin assembly protein complex 2 medium chain; clathrin assembly protein complex 2 mu medium chain; clathrin coat assembly protein AP50; clathrin coat-associated protein AP50; coat assembly protein complex 50 kD; coat assembly protein complex, 50 kD; MGC105352; mu2; mu2-adaptin; plasma membrane adaptor AP-2 50 kDa protein
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01184,041,184 - 84,047,542 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01187,113,496 - 87,119,854 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,585,474 - 82,591,832 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11182,643,062 - 82,649,421 (-)NCBI
Celera1179,194,852 - 79,201,210 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ap2m1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620135
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.