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Gene: Fan1 (FANCD2 and FANCI associated nuclease 1) Rattus norvegicus
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Symbol: Fan1
Name: FANCD2 and FANCI associated nuclease 1
RGD ID: 1566323
Description: Predicted to have flap-structured DNA binding activity; nuclease activity; and ubiquitin-dependent protein binding activity. Predicted to be involved in double-strand break repair via homologous recombination; interstrand cross-link repair; and nucleotide-excision repair, DNA incision. Predicted to localize to cytosol; intercellular bridge; and nucleoplasm. Human ortholog(s) of this gene implicated in karyomegalic interstitial nephritis. Orthologous to human FAN1 (FANCD2 and FANCI associated nuclease 1); INTERACTS WITH (-)-epigallocatechin 3-gallate; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: coiled-coil domain-containing protein MTMR15; FANCD2/FANCI-associated nuclease 1; fanconi-associated nuclease 1; LOC309256; Mtmr15; myotubularin related protein 15; RGD1566323; similar to mKIAA1018 protein
Orthologs:
Homo sapiens (human) : FAN1 (FANCD2 and FANCI associated nuclease 1)  HGNC  Alliance
Mus musculus (house mouse) : Fan1 (FANCD2/FANCI-associated nuclease 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fan1 (FANCD2 and FANCI associated nuclease 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FAN1 (FANCD2 and FANCI associated nuclease 1)
Canis lupus familiaris (dog) : FAN1 (FANCD2 and FANCI associated nuclease 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fan1 (FANCD2 and FANCI associated nuclease 1)
Sus scrofa (pig) : FAN1 (FANCD2 and FANCI associated nuclease 1)
Chlorocebus sabaeus (African green monkey) : FAN1 (FANCD2 and FANCI associated nuclease 1)
Heterocephalus glaber (naked mole-rat) : Fan1 (FANCD2 and FANCI associated nuclease 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01125,182,117 - 125,209,772 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1125,181,838 - 125,209,727 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01126,291,169 - 126,318,945 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41118,784,938 - 118,811,928 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1110,174,511 - 110,199,745 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Fan1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1566323
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.