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Gene: Klk5 (kallikrein related-peptidase 5) Rattus norvegicus
Symbol: Klk5
Name: kallikrein related-peptidase 5
Description: Predicted to have serine-type endopeptidase activity. Predicted to be involved in positive regulation of G protein-coupled receptor signaling pathway and positive regulation of antibacterial peptide production. Predicted to localize to epidermal lamellar body and extracellular space. Orthologous to human KLK5 (kallikrein related peptidase 5); INTERACTS WITH (S)-nicotine (ortholog); 2-hydroxypropanoic acid (ortholog); calcitriol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: kallikrein 5; kallikrein-5; kallikrein-5-like; LOC102546758; LOC690603; similar to kallikrein 5 preproprotein
Homo sapiens (human) : KLK5 (kallikrein related peptidase 5)  HGNC  Alliance
Mus musculus (house mouse) : Klk5 (kallikrein related-peptidase 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klk5 (kallikrein related peptidase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : KLK5 (kallikrein related peptidase 5)
Canis lupus familiaris (dog) : KLK5 (kallikrein related peptidase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klk5 (kallikrein related peptidase 5)
Sus scrofa (pig) : KLK5 (kallikrein related peptidase 5)
Chlorocebus sabaeus (African green monkey) : KLK5 (kallikrein related peptidase 5)
Heterocephalus glaber (naked mole-rat) : Klk5 (kallikrein related peptidase 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0199,781,291 - 99,793,745 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,781,237 - 99,786,330 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01100,849,440 - 100,862,007 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,273,869 - 94,281,384 (+)NCBIRGSC3.4rn4RGSC3.4
Celera188,564,667 - 88,573,574 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Klk5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593461
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.