Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Det1 (DET1 partner of COP1 E3 ubiquitin ligase) Rattus norvegicus
Symbol: Det1
Name: DET1 partner of COP1 E3 ubiquitin ligase
Description: Predicted to have ubiquitin ligase-substrate adaptor activity and ubiquitin protein ligase binding activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; and protein-containing complex assembly. Predicted to localize to Cul4A-RING E3 ubiquitin ligase complex. Orthologous to human DET1 (DET1 partner of COP1 E3 ubiquitin ligase); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2-methoxyethanol; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
Also known as: de-etiolated homolog 1; de-etiolated homolog 1 (Arabidopsis); DET1 homolog; DET1, COP1 ubiquitin ligase partner; LOC308775; MGC116189; RGD1309793; similar to RIKEN cDNA 2610034H20
Homo sapiens (human) : DET1 (DET1 partner of COP1 E3 ubiquitin ligase)  HGNC  Alliance
Mus musculus (house mouse) : Det1 (de-etiolated homolog 1 (Arabidopsis))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Det1 (DET1 partner of COP1 E3 ubiquitin ligase)
Pan paniscus (bonobo/pygmy chimpanzee) : DET1 (DET1 partner of COP1 E3 ubiquitin ligase)
Canis lupus familiaris (dog) : DET1 (DET1 partner of COP1 E3 ubiquitin ligase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Det1 (DET1 partner of COP1 E3 ubiquitin ligase)
Sus scrofa (pig) : DET1 (DET1 partner of COP1 E3 ubiquitin ligase)
Chlorocebus sabaeus (African green monkey) : DET1 (DET1 partner of COP1 E3 ubiquitin ligase)
Heterocephalus glaber (naked mole-rat) : Det1 (DET1 partner of COP1 E3 ubiquitin ligase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01140,519,755 - 140,535,969 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1140,519,702 - 140,535,934 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,494,829 - 141,511,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41134,552,235 - 134,566,070 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11134,627,799 - 134,653,445 (-)NCBI
Celera1124,823,167 - 124,836,180 (-)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Det1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309793
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.