Csrp3 (cysteine and glycine rich protein 3)

Gene: Csrp3 (cysteine and glycine rich protein 3) Rattus norvegicus

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Symbol:

Csrp3

Name:

cysteine and glycine rich protein 3

Description:

Exhibits MRF binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in blood vessel remodeling; positive regulation of DNA-binding transcription factor activity; and positive regulation of myotube differentiation. Localizes to the Z disc and nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1M; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 12. Orthologous to human CSRP3 (cysteine and glycine rich protein 3); INTERACTS WITH (RS)-amphetamine; 1-benzylpiperazine; 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

CRP3; cysteine and glycine rich protein 3 c-terminal HA-tagged; cysteine and glycine rich protein 3 lacking the LIM1-domain; cysteine and glycine rich protein 3 N-terminal nuclear localization sequence; cysteine and glycine-rich protein 3; cysteine and glycine-rich protein 3 (cardiac LIM protein); cysteine-rich protein 3; LIM domain protein, cardiac; MLP; muscle LIM protein

Orthologs:

Homo sapiens (human) : CSRP3 (cysteine and glycine rich protein 3) HGNC Alliance
Mus musculus (house mouse) : Csrp3 (cysteine and glycine-rich protein 3) MGI Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csrp3 (cysteine and glycine rich protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CSRP3 (cysteine and glycine rich protein 3)
Canis lupus familiaris (dog) : CSRP3 (cysteine and glycine rich protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csrp3 (cysteine and glycine rich protein 3)
Sus scrofa (pig) : CSRP3 (cysteine and glycine rich protein 3)

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CSRP3 (cysteine and glycine rich protein 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Csrp3 (cysteine and glycine-rich protein 3)	HGNC	Treefam, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Csrp3 (cysteine and glycine rich protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CSRP3 (cysteine and glycine rich protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CSRP3 (cysteine and glycine rich protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Csrp3 (cysteine and glycine rich protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CSRP3 (cysteine and glycine rich protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CSRP3 (cysteine and glycine rich protein 3)	Alliance	DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Mus musculus (house mouse):	Csrp3 (cysteine and glycine-rich protein 3)	Alliance	DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):	csrp3 (cysteine and glycine-rich protein 3 (cardiac LIM protein))	Alliance	DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Caenorhabditis elegans (roundworm):	mlp-1	Alliance	DIOPT (Ensembl Compara, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Mlp60A	Alliance	DIOPT (Ensembl Compara, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Mlp84B	Alliance	DIOPT (Ensembl Compara, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	1	104,147,205 - 104,166,389 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	105,206,459 - 105,225,635 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	98,601,681 - 98,611,747 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	98,679,791 - 98,689,858 (-)	NCBI
Celera	1	92,735,902 - 92,745,962 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

JBrowse:

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Gene Ontology Annotations

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Genomics

Comparative Map Data

Position Markers

QTLs in Region (Rnor_6.0)

miRNA Target Status

Sequence

Nucleotide Sequences

Protein Sequences

Transcriptome

Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links

Nomenclature History

RGD Curation Notes

More on Csrp3
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: rn5 rn6
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	71092
Created:	2002-07-09
Species:	Rattus norvegicus
Last Modified:	2019-04-23
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

Functional Annotation unavailable	Annotation Distribution unavailable	Genomic Variants unavailble for Mouse Genomic Variants unavailable
Functional Annotation	Annotation Distribution	Genomic Variants

Protein-Protein Interactions unavailable	Genome Viewer unavailable	Damaging Variants unavailble for Mouse Damaging Variants unavailable
Protein-Protein Interactions	Genome Viewer	Damaging Variants

Annotation Comparison unavailable	OLGA unavailable
Annotation Comparison	OLGA	Excel (Download)

Gene Enrichment unavailable
Gene Enrichment

RGD Manual Annotations

Imported Annotations - ClinVar

Imported Annotations - CTD

Imported Annotations - MGI

Imported Annotations - OMIM