Gene: Ctsc (cathepsin C) Rattus norvegicus
Analyze
Symbol:
Ctsc
Name:
cathepsin C
Description:
Exhibits several functions, including chaperone binding activity; chloride ion binding activity; and identical protein binding activity. Involved in several processes, including aging; positive regulation of proteolysis involved in cellular protein catabolic process; and proteolysis. Localizes to the Golgi apparatus; endoplasmic reticulum; and lysosome. Biomarker of brain ischemia; hypertension; and obesity. Human ortholog(s) of this gene implicated in Papillon-Lefevre disease and aggressive periodontitis. Orthologous to human CTSC (cathepsin C); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
CATC; Cathepsin C (dipeptidyl peptidase I); cathepsin J; dipeptidyl peptidase 1; dipeptidyl peptidase I; dipeptidyl transferase; dipeptidyl-peptidase 1; dipeptidyl-peptidase I; DPP-I; DPPI
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
CTSC (cathepsin C) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Ctsc (cathepsin C) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Ctsc (cathepsin C) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
CTSC (cathepsin C) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
CTSC (cathepsin C) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ctsc (cathepsin C) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
CTSC (cathepsin C) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Ctsc (cathepsin C)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):
CTSC (cathepsin C)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
ctsc (cathepsin C)
Alliance
DIOPT (Ensembl Compara, Hieranoid, OMA, OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Is Marker For:
Strains:
FHH.BN-(D1Hmgc14-D1Hmgc15 )/Mcwi
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 1 151,918,514 - 151,949,979 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 151,918,571 - 151,949,983 (+) Ensembl Rnor_5.0 1 158,231,534 - 158,263,124 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 144,629,802 - 144,661,183 (+) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 1 144,708,207 - 144,739,589 (+) NCBI Celera 1 140,327,884 - 140,359,275 (+) NCBI Celera Cytogenetic Map 1 q32 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
aggressive periodontitis ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:170650 ClinVar PMID:10581027 , PMID:10662808 aggressive periodontitis ISO RGD:736291 8554872 ClinVar Annotator: match by term: Periodontitis, aggressive, 1 ClinVar PMID:14974080 more ... aggressive periodontitis ISO RGD:736291 8554872 ClinVar Annotator: match by term: Periodontitis, aggressive, 1 ClinVar PMID:25741868 aggressive periodontitis ISO RGD:736291 8554872 ClinVar Annotator: match by term: Aggressive Periodontitis ClinVar PMID:28492532 aggressive periodontitis ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:170650 ClinVar PMID:14974080 Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 8554872 ClinVar Annotator: match by term: Haim-Munk syndrome ClinVar PMID:11886537 , PMID:28492532 Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 8554872 ClinVar Annotator: match by term: Haim-Munk syndrome ClinVar PMID:18945301 , PMID:28492532 Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 8554872 ClinVar Annotator: match by term: Haim-Munk syndrome ClinVar PMID:10593994 more ... Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 8554872 ClinVar Annotator: match by term: Haim-Munk syndrome ClinVar PMID:11180601 , PMID:24936511 Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 8554872 ClinVar Annotator: match by term: Haim-Munk syndrome ClinVar PMID:14974080 more ... Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 8554872 ClinVar Annotator: match by term: Haim-Munk syndrome ClinVar PMID:24033266 , PMID:25741868 Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:245010 ClinVar PMID:25741868 Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:245010 ClinVar Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:245010 ClinVar PMID:10662807 Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 8554872 ClinVar Annotator: match by term: Haim-Munk syndrome ClinVar PMID:28492532 Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by term: Papillon-Lefevre Disease ClinVar PMID:14974080 more ... Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by term: Papillon-Lefevre Disease ClinVar PMID:28492532 Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by term: Papillon-Lefevre Disease ClinVar PMID:11180601 , PMID:24936511 Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by term: Papillon-Lefevre Disease ClinVar PMID:14974080 more ... Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by term: Papillon-Lefevre Disease ClinVar PMID:24033266 , PMID:25741868 Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by term: Papillon-Lefevre Disease ClinVar PMID:25741868 Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:245000 ClinVar Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:245000 ClinVar PMID:11886537 Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:245000 ClinVar PMID:10581027 Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:245000 ClinVar PMID:10593994 Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:245000 ClinVar PMID:11180012 Papillon-Lefevre disease ISO RGD:736291 8554872 ClinVar Annotator: match by OMIM:245000 ClinVar PMID:10581027 , PMID:10662808
Imported Annotations - CTD
allergic contact dermatitis ISO RGD:736291 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:17374397 Disease Progression ISO RGD:736291 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21364753 Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:10662807 Myocardial Ischemia ISO RGD:736291 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:16214533 Papillon-Lefevre disease ISO RGD:736291 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:10662807 , PMID:16008657 periodontal disease ISO RGD:736291 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:10662807 Stomach Neoplasms ISO RGD:736291 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21364753 Imported Annotations - MGI
schizophrenia ISS RGD:10421 13592920 OMIM:181500 MouseDO Imported Annotations - OMIM
aggressive periodontitis ISO RGD:736291 7240710 OMIM Keratosis Palmoplantaris with Periodontopathia and Onychogryposis ISO RGD:736291 7240710 OMIM Papillon-Lefevre disease ISO RGD:736291 7240710 OMIM
(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CTSC mRNA] CTD PMID:31150632 1,1-dichloroethene increases expression ISO RGD:10421 6480464 vinylidene chloride results in increased expression of CTSC mRNA CTD PMID:26682919 1-chloro-2,4-dinitrobenzene decreases expression ISO RGD:736291 6480464 Dinitrochlorobenzene results in decreased expression of CTSC mRNA CTD PMID:17374397 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of CTSC mRNA CTD PMID:16940010 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of CTSC mRNA CTD PMID:16940010 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of CTSC mRNA CTD PMID:16940010 17beta-estradiol increases expression ISO RGD:736291 6480464 Estradiol results in increased expression of CTSC mRNA CTD PMID:21185374 17beta-estradiol increases expression ISO RGD:10421 6480464 Estradiol results in increased expression of CTSC mRNA CTD PMID:15289156 , PMID:19484750 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:736291 6480464 2 more ... CTD PMID:19095052 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:20056577 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:736291 6480464 Tetrachlorodibenzodioxin results in decreased expression of CTSC mRNA CTD PMID:17101203 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:736291 6480464 Tetrachlorodibenzodioxin results in increased expression of CTSC mRNA CTD PMID:20106945 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CTSC mRNA CTD PMID:16054898 , PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10421 6480464 Tetrachlorodibenzodioxin results in decreased expression of CTSC mRNA CTD PMID:19933214 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:10421 6480464 Trinitrobenzenesulfonic Acid results in increased expression of CTSC mRNA CTD PMID:17982090 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of CTSC mRNA CTD PMID:21346803 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of CTSC mRNA CTD PMID:28522335 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:736291 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CTSC mRNA CTD PMID:28628672 4-(ethoxymethylene)-2-phenyloxazol-5-one decreases expression ISO RGD:736291 6480464 Oxazolone results in decreased expression of CTSC mRNA CTD PMID:17374397 4-hydroxyphenyl retinamide decreases expression ISO RGD:10421 6480464 Fenretinide results in decreased expression of CTSC mRNA CTD PMID:28973697 adefovir pivoxil decreases expression ISO RGD:736291 6480464 adefovir dipivoxil results in decreased expression of CTSC mRNA CTD PMID:25596134 aflatoxin B1 increases expression ISO RGD:736291 6480464 Aflatoxin B1 results in increased expression of CTSC mRNA CTD PMID:27153756 all-trans-retinoic acid decreases expression ISO RGD:736291 6480464 Tretinoin results in decreased expression of CTSC mRNA CTD PMID:23724009 alpha-hexachlorocyclohexane decreases expression EXP 6480464 alpha-hexachlorocyclohexane results in decreased expression of CTSC mRNA CTD PMID:16940010 alpha-hexachlorocyclohexane increases expression EXP 6480464 alpha-hexachlorocyclohexane results in increased expression of CTSC mRNA CTD PMID:16940010 alpha-hexachlorocyclohexane affects expression EXP 6480464 alpha-hexachlorocyclohexane affects the expression of CTSC mRNA CTD PMID:16940010 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CTSC mRNA CTD PMID:16483693 amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of CTSC mRNA CTD PMID:30779732 antirheumatic drug decreases expression ISO RGD:736291 6480464 Antirheumatic Agents results in decreased expression of CTSC mRNA CTD PMID:24449571 arsenous acid decreases expression ISO RGD:736291 6480464 Arsenic Trioxide results in decreased expression of CTSC mRNA CTD PMID:26705709 benzo[a]pyrene decreases expression ISO RGD:10421 6480464 Benzo(a)pyrene results in decreased expression of CTSC mRNA CTD PMID:19770486 benzo[a]pyrene increases expression ISO RGD:736291 6480464 Benzo(a)pyrene results in increased expression of CTSC mRNA CTD PMID:26238291 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CTSC mRNA CTD PMID:18164116 bis(2-ethylhexyl) phthalate increases expression ISO RGD:10421 6480464 Diethylhexyl Phthalate results in increased expression of CTSC mRNA CTD PMID:19850644 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CTSC mRNA CTD PMID:15901920 bisphenol A affects expression ISO RGD:736291 6480464 bisphenol A affects the expression of CTSC mRNA CTD PMID:30903817 bisphenol A multiple interactions ISO RGD:736291 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CTSC mRNA CTD PMID:28628672 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CTSC mRNA CTD PMID:25181051 butanal increases expression ISO RGD:736291 6480464 butyraldehyde results in increased expression of CTSC mRNA CTD PMID:26079696 cadmium dichloride increases expression ISO RGD:736291 6480464 Cadmium Chloride results in increased expression of CTSC mRNA, Cadmium Chloride results in increased expression of CTSC protein CTD PMID:24527689 , PMID:25596134 cadmium dichloride decreases expression ISO RGD:736291 6480464 Cadmium Chloride results in decreased expression of CTSC mRNA CTD PMID:26472689 carbon nanotube increases expression ISO RGD:10421 6480464 Nanotubes, Carbon analog results in increased expression of CTSC mRNA, Nanotubes, Carbon results in increased expression of CTSC mRNA CTD PMID:25554681 carbon nanotube decreases expression ISO RGD:10421 6480464 Nanotubes, Carbon results in decreased expression of CTSC mRNA CTD PMID:25620056 chloroprene decreases expression ISO RGD:10421 6480464 Chloroprene results in decreased expression of CTSC mRNA CTD PMID:23125180 choline multiple interactions ISO RGD:10421 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CTSC gene CTD PMID:20938992 cidofovir anhydrous increases expression ISO RGD:736291 6480464 Cidofovir results in increased expression of CTSC mRNA CTD PMID:25596134 ciglitazone multiple interactions ISO RGD:736291 6480464 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CTSC mRNA CTD PMID:16197558 cisplatin increases expression ISO RGD:736291 6480464 Cisplatin results in increased expression of CTSC mRNA CTD PMID:25596134 cisplatin multiple interactions ISO RGD:736291 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of CTSC mRNA CTD PMID:27392435 clodronic acid increases expression ISO RGD:736291 6480464 Clodronic Acid results in increased expression of CTSC mRNA CTD PMID:25596134 clofibrate multiple interactions ISO RGD:10421 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CTSC mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CTSC mRNA] CTD PMID:17585979 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CTSC mRNA CTD PMID:17602206 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of CTSC mRNA CTD PMID:24386269 cobalt dichloride decreases expression ISO RGD:736291 6480464 cobaltous chloride results in decreased expression of CTSC mRNA CTD PMID:19320972 , PMID:19376846 copper(II) sulfate decreases expression ISO RGD:736291 6480464 Copper Sulfate results in decreased expression of CTSC mRNA CTD PMID:19549813 coumestrol increases expression ISO RGD:736291 6480464 Coumestrol results in increased expression of CTSC mRNA CTD PMID:19167446 cyclosporin A decreases expression ISO RGD:736291 6480464 Cyclosporine results in decreased expression of CTSC mRNA CTD PMID:25596134 dexamethasone multiple interactions ISO RGD:736291 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CTSC mRNA CTD PMID:28628672 diarsenic trioxide decreases expression ISO RGD:736291 6480464 Arsenic Trioxide results in decreased expression of CTSC mRNA CTD PMID:26705709 diclofenac increases expression ISO RGD:10421 6480464 Diclofenac results in increased expression of CTSC mRNA CTD PMID:26934552 diethylstilbestrol increases expression ISO RGD:10421 6480464 Diethylstilbestrol results in increased expression of CTSC mRNA CTD PMID:15289156 dioxygen decreases expression ISO RGD:736291 6480464 Oxygen deficiency results in decreased expression of CTSC mRNA CTD PMID:25596134 dorsomorphin multiple interactions ISO RGD:736291 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of CTSC mRNA CTD PMID:29391264 entinostat increases expression ISO RGD:736291 6480464 entinostat results in increased expression of CTSC mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:736291 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTSC mRNA CTD PMID:27188386 fenofibrate decreases expression EXP 6480464 Fenofibrate results in decreased expression of CTSC mRNA CTD PMID:25596134 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of CTSC mRNA CTD PMID:18035473 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of CTSC mRNA CTD PMID:24136188 folic acid affects expression ISO RGD:736291 6480464 Folic Acid affects the expression of CTSC mRNA CTD PMID:17320366 folic acid multiple interactions ISO RGD:10421 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CTSC gene CTD PMID:20938992 genistein increases expression ISO RGD:10421 6480464 Genistein results in increased expression of CTSC mRNA CTD PMID:15289156 genistein increases expression ISO RGD:736291 6480464 Genistein results in increased expression of CTSC mRNA CTD PMID:20884965 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of CTSC mRNA CTD PMID:22061828 hydrazine increases expression ISO RGD:10421 6480464 hydrazine results in increased expression of CTSC mRNA CTD PMID:15282401 ibuprofen decreases expression EXP 6480464 Ibuprofen results in decreased expression of CTSC mRNA CTD PMID:25596134 ibuprofen decreases expression ISO RGD:736291 6480464 Ibuprofen results in decreased expression of CTSC mRNA CTD PMID:25596134 ifosfamide increases expression ISO RGD:736291 6480464 Ifosfamide results in increased expression of CTSC mRNA CTD PMID:25596134 indometacin multiple interactions ISO RGD:736291 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CTSC mRNA CTD PMID:28628672 L-methionine multiple interactions ISO RGD:10421 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CTSC gene CTD PMID:20938992 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of CTSC mRNA CTD PMID:22641619 lipopolysaccharide increases expression ISO RGD:10421 6480464 Lipopolysaccharides results in increased expression of CTSC mRNA CTD PMID:27339419 mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of CTSC mRNA CTD PMID:16507785 metformin decreases expression EXP 6480464 Metformin results in decreased expression of CTSC mRNA CTD PMID:25596134 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of CTSC mRNA CTD PMID:30467583 methyl methanesulfonate decreases expression ISO RGD:736291 6480464 Methyl Methanesulfonate results in decreased expression of CTSC mRNA CTD PMID:23649840 methylmercury chloride increases expression ISO RGD:736291 6480464 methylmercuric chloride results in increased expression of CTSC mRNA CTD PMID:23179753 more ... methylmercury chloride multiple interactions ISO RGD:736291 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTSC mRNA CTD PMID:27188386 mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of CTSC mRNA CTD PMID:25972201 N-nitrosodiethylamine decreases expression ISO RGD:10421 6480464 Diethylnitrosamine results in decreased expression of CTSC mRNA CTD PMID:17942915 N-nitrosodiethylamine increases expression ISO RGD:10421 6480464 Diethylnitrosamine results in increased expression of CTSC mRNA CTD PMID:24535843 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CTSC mRNA, [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CTSC mRNA CTD PMID:17602206 , PMID:18164116 N-nitrosodiethylamine multiple interactions ISO RGD:10421 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CTSC mRNA, MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CTSC mRNA] CTD PMID:17942915 , PMID:24535843 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of CTSC mRNA CTD PMID:24136188 nickel atom increases expression ISO RGD:736291 6480464 Nickel results in increased expression of CTSC mRNA CTD PMID:25583101 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of CTSC mRNA CTD PMID:22110744 nickel sulfate decreases expression ISO RGD:736291 6480464 nickel sulfate results in decreased expression of CTSC mRNA CTD PMID:16780908 more ... Niclosamide decreases expression ISO RGD:736291 6480464 Niclosamide results in decreased expression of CTSC protein CTD PMID:29480568 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of CTSC mRNA CTD PMID:25729387 oxycodone decreases expression EXP 6480464 Oxycodone results in decreased expression of CTSC mRNA CTD PMID:23439660 paracetamol multiple interactions ISO RGD:10421 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CTSC mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CTSC mRNA] CTD PMID:17585979 paracetamol decreases expression ISO RGD:736291 6480464 Acetaminophen results in decreased expression of CTSC mRNA CTD PMID:21420995 paracetamol affects expression ISO RGD:10421 6480464 Acetaminophen affects the expression of CTSC mRNA CTD PMID:17562736 paraquat decreases expression ISO RGD:10421 6480464 Paraquat results in decreased expression of CTSC mRNA CTD PMID:16797015 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of CTSC mRNA CTD PMID:19162173 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of CTSC mRNA CTD PMID:19162173 perfluorooctanoic acid multiple interactions ISO RGD:10421 6480464 PPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of CTSC mRNA] CTD PMID:18467677 , PMID:20936131 perfluorooctanoic acid decreases expression ISO RGD:10421 6480464 perfluorooctanoic acid results in decreased expression of CTSC mRNA CTD PMID:18467677 , PMID:20936131 phenobarbital decreases expression ISO RGD:10421 6480464 Phenobarbital results in decreased expression of CTSC mRNA CTD PMID:19482888 phenobarbital multiple interactions ISO RGD:10421 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CTSC mRNA, NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of CTSC mRNA] CTD PMID:19482888 , PMID:24535843 phenylephrine decreases expression EXP 6480464 Phenylephrine results in decreased expression of CTSC mRNA CTD PMID:18158353 phenylmercury acetate multiple interactions ISO RGD:736291 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTSC mRNA CTD PMID:27188386 pirimiphos-methyl decreases activity EXP 6480464 pirimiphos methyl results in decreased activity of CTSC protein CTD PMID:9204212 pirimiphos-methyl increases activity EXP 6480464 pirimiphos methyl results in increased activity of CTSC protein CTD PMID:9204212 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of CTSC mRNA CTD PMID:19162173 pirinixic acid decreases expression ISO RGD:10421 6480464 pirinixic acid results in decreased expression of CTSC mRNA CTD PMID:16221962 more ... piroxicam decreases expression ISO RGD:736291 6480464 Piroxicam results in decreased expression of CTSC mRNA CTD PMID:21858171 quercetin increases expression ISO RGD:736291 6480464 Quercetin results in increased expression of CTSC mRNA CTD PMID:21632981 rotenone increases expression ISO RGD:10421 6480464 Rotenone results in increased expression of CTSC mRNA CTD PMID:23186747 SB 431542 multiple interactions ISO RGD:736291 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silver atom decreases expression ISO RGD:10421 6480464 Silver results in decreased expression of CTSC mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:10421 6480464 Silver results in decreased expression of CTSC mRNA CTD PMID:27131904 sodium arsenite decreases expression ISO RGD:736291 6480464 sodium arsenite results in decreased expression of CTSC mRNA CTD PMID:28595984 sodium arsenite increases expression ISO RGD:10421 6480464 sodium arsenite results in increased expression of CTSC protein CTD PMID:29044176 sodium arsenite increases expression ISO RGD:736291 6480464 sodium arsenite results in increased expression of CTSC mRNA CTD PMID:12760830 sodium fluoride increases expression ISO RGD:10421 6480464 Sodium Fluoride results in increased expression of CTSC protein CTD PMID:28918527 Soman increases expression EXP 6480464 Soman results in increased expression of CTSC mRNA CTD PMID:19281266 sulindac sulfide decreases expression ISO RGD:736291 6480464 sulindac sulfide results in decreased expression of CTSC mRNA CTD PMID:16184548 tamoxifen decreases expression ISO RGD:10421 6480464 Tamoxifen results in decreased expression of CTSC mRNA CTD PMID:25123088 tamoxifen affects expression ISO RGD:10421 6480464 Tamoxifen affects the expression of CTSC mRNA CTD PMID:20937368 testosterone decreases expression ISO RGD:10421 6480464 Testosterone results in decreased expression of CTSC mRNA CTD PMID:20403060 , PMID:21669218 tetrachloroethene increases expression ISO RGD:10421 6480464 Tetrachloroethylene results in increased expression of CTSC mRNA CTD PMID:28973375 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CTSC mRNA] CTD PMID:31150632 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of CTSC mRNA CTD PMID:31150632 titanium dioxide increases expression ISO RGD:10421 6480464 titanium dioxide results in increased expression of CTSC mRNA CTD PMID:23557971 , PMID:27760801 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of CTSC mRNA CTD PMID:25729387 trichostatin A increases expression ISO RGD:736291 6480464 trichostatin A results in increased expression of CTSC mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:736291 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTSC mRNA CTD PMID:27188386 trimellitic anhydride increases expression ISO RGD:10421 6480464 trimellitic anhydride results in increased expression of CTSC mRNA CTD PMID:19042947 troglitazone increases expression ISO RGD:10421 6480464 troglitazone results in increased expression of CTSC mRNA CTD PMID:28973697 valproic acid affects expression ISO RGD:736291 6480464 Valproic Acid affects the expression of CTSC mRNA CTD PMID:25979313 valproic acid multiple interactions ISO RGD:736291 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTSC mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:736291 6480464 Valproic Acid results in increased expression of CTSC mRNA CTD PMID:23179753 more ... valproic acid decreases expression ISO RGD:736291 6480464 Valproic Acid results in decreased expression of CTSC mRNA CTD PMID:24935251 vancomycin decreases expression ISO RGD:10421 6480464 Vancomycin results in decreased expression of CTSC mRNA CTD PMID:18930951 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of CTSC mRNA CTD PMID:19015723 vorinostat multiple interactions ISO RGD:736291 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTSC mRNA CTD PMID:27188386 XL147 multiple interactions ISO RGD:10421 6480464 XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CTSC mRNA] CTD PMID:29891994 zoledronic acid increases expression ISO RGD:736291 6480464 zoledronic acid results in increased expression of CTSC mRNA CTD PMID:25596134
Gene-Chemical Interaction Annotations
