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Gene: Sox6 (SRY box 6) Rattus norvegicus
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Symbol: Sox6
Name: SRY box 6
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and protein heterodimerization activity. Involved in astrocyte differentiation. Predicted to localize to the nucleoplasm. Human ortholog(s) of this gene implicated in malignant glioma. Orthologous to human SOX6 (SRY-box 6); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: SRY (sex determining region Y)-box 6; SRY-box containing gene 6; transcription factor SOX-6
Orthologs:
Homo sapiens (human) : SOX6 (SRY-box transcription factor 6)  HGNC  Alliance
Mus musculus (house mouse) : Sox6 (SRY (sex determining region Y)-box 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox6 (SRY-box transcription factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX6 (SRY-box transcription factor 6)
Canis lupus familiaris (dog) : SOX6 (SRY-box 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox6 (SRY-box transcription factor 6)
Sus scrofa (pig) : SOX6 (SRY-box transcription factor 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01185,631,702 - 186,186,192 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01192,644,288 - 193,155,831 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41173,556,966 - 174,069,437 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11173,696,212 - 174,208,683 (-)NCBI
Celera1167,560,079 - 168,058,656 (-)NCBICelera
Cytogenetic Map1q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Sox6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309000
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.