Ruvbl2 (RuvB-like AAA ATPase 2) - Rat Genome Database

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Gene: Ruvbl2 (RuvB-like AAA ATPase 2) Rattus norvegicus
Analyze
Symbol: Ruvbl2
Name: RuvB-like AAA ATPase 2
RGD ID: 1306509
Description: Predicted to enable several functions, including adenyl ribonucleotide binding activity; double-stranded DNA binding activity; and general transcription initiation factor binding activity. Predicted to be involved in several processes, including box C/D snoRNP assembly; cellular response to estradiol stimulus; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be part of several cellular components, including MLL1 complex; R2TP complex; and chromatin. Orthologous to human RUVBL2 (RuvB like AAA ATPase 2); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC292907; RuvB-like 2; RuvB-like 2 (E. coli); RuvB-like protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Ruvbl2-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,038,487 - 105,051,851 (-)NCBIGRCr8
mRatBN7.2195,902,014 - 95,915,247 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,901,701 - 95,915,342 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,287,438 - 101,300,671 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,760,116 - 109,773,349 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,050,515 - 103,063,748 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,413,766 - 101,426,970 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,413,766 - 101,426,852 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,493,176 - 102,506,380 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,894,029 - 95,906,885 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,972,140 - 95,985,010 (-)NCBI
Celera190,157,605 - 90,170,691 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dinitrotoluene  (EXP)
3,3'-Dichlorobenzidine  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
DDE  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
fenthion  (ISO)
flutamide  (EXP)
geraniol  (ISO)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
hypochlorous acid  (ISO)
imiquimod  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
linalool  (ISO)
lovastatin  (ISO)
methidathion  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
selenium atom  (ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
T-2 toxin  (EXP,ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiophenes  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics. Watanabe S and Peterson CL, Cold Spring Harb Symp Quant Biol. 2010;75:35-42. doi: 10.1101/sqb.2010.75.063. Epub 2011 Apr 18.
Additional References at PubMed
PMID:10524211   PMID:10966108   PMID:11080158   PMID:14966270   PMID:15960975   PMID:17353931   PMID:17636026   PMID:18026119   PMID:19299493   PMID:19433865   PMID:20458337   PMID:21303910  
PMID:21799128   PMID:21988832   PMID:22748767   PMID:23376485   PMID:23637611   PMID:24463511   PMID:24625528   PMID:25467444   PMID:26711270  


Genomics

Comparative Map Data
Ruvbl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,038,487 - 105,051,851 (-)NCBIGRCr8
mRatBN7.2195,902,014 - 95,915,247 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,901,701 - 95,915,342 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,287,438 - 101,300,671 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,760,116 - 109,773,349 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,050,515 - 103,063,748 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,413,766 - 101,426,970 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,413,766 - 101,426,852 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,493,176 - 102,506,380 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,894,029 - 95,906,885 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,972,140 - 95,985,010 (-)NCBI
Celera190,157,605 - 90,170,691 (-)NCBICelera
Cytogenetic Map1q22NCBI
RUVBL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,993,448 - 49,015,995 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,993,562 - 49,015,970 (+)EnsemblGRCh38hg38GRCh38
GRCh371949,496,705 - 49,519,252 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,188,968 - 54,210,994 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,188,967 - 54,210,994NCBI
Celera1946,364,487 - 46,386,389 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,873,862 - 45,895,902 (+)NCBIHuRef
CHM1_11949,499,385 - 49,521,406 (+)NCBICHM1_1
T2T-CHM13v2.01951,988,347 - 52,010,769 (+)NCBIT2T-CHM13v2.0
Ruvbl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,071,320 - 45,084,817 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,071,184 - 45,087,520 (-)EnsemblGRCm39 Ensembl
GRCm38745,421,896 - 45,436,171 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,421,760 - 45,438,096 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,677,268 - 52,689,834 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,290,000 - 45,302,337 (-)NCBIMGSCv36mm8
Celera740,877,932 - 40,890,498 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.3NCBI
Ruvbl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,654,059 - 1,674,272 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,657,241 - 1,674,272 (-)NCBIChiLan1.0ChiLan1.0
RUVBL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,099,261 - 55,121,683 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,025,412 - 57,047,842 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,995,394 - 46,017,835 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,739,474 - 54,761,407 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,739,474 - 54,761,407 (-)Ensemblpanpan1.1panPan2
RUVBL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,384,328 - 107,400,849 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,384,342 - 107,400,505 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,910,707 - 106,923,430 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,908,904 - 107,925,482 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,908,893 - 107,925,182 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,576,740 - 107,593,066 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,222,909 - 107,239,405 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,058,521 - 108,075,019 (-)NCBIUU_Cfam_GSD_1.0
Ruvbl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,377,118 - 21,392,373 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,995,213 - 3,010,853 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,995,212 - 3,010,563 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RUVBL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,250,515 - 54,266,893 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,250,494 - 54,263,492 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,065,154 - 50,078,153 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RUVBL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,227,982 - 42,247,204 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,227,821 - 42,249,707 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,110,661 - 22,134,370 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ruvbl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,014,484 - 5,028,885 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,014,484 - 5,028,868 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ruvbl2
14 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:100
Count of miRNA genes:84
Interacting mature miRNAs:93
Transcripts:ENSRNOT00000028217
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)194494440117601394Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat

Markers in Region
RH141058  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,902,281 - 95,902,816 (+)MAPPERmRatBN7.2
Rnor_6.01101,414,034 - 101,414,568NCBIRnor6.0
Rnor_5.01102,493,444 - 102,493,978UniSTSRnor5.0
RGSC_v3.4195,894,297 - 95,894,831UniSTSRGSC3.4
Celera190,157,873 - 90,158,407UniSTS
RH 3.4 Map1908.5UniSTS
Cytogenetic Map1q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000028217   ⟹   ENSRNOP00000028217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,902,014 - 95,915,342 (-)Ensembl
Rnor_6.0 Ensembl1101,413,766 - 101,426,852 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097056   ⟹   ENSRNOP00000079618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,902,014 - 95,914,889 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111472   ⟹   ENSRNOP00000088524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,901,701 - 95,911,440 (-)Ensembl
RefSeq Acc Id: NM_001025405   ⟹   NP_001020576
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,038,487 - 105,051,720 (-)NCBI
mRatBN7.2195,902,014 - 95,915,247 (-)NCBI
Rnor_6.01101,413,766 - 101,426,852 (-)NCBI
Rnor_5.01102,493,176 - 102,506,380 (-)NCBI
RGSC_v3.4195,894,029 - 95,906,885 (-)RGD
Celera190,157,605 - 90,170,691 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105046   ⟹   XP_038960974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,038,487 - 105,051,313 (-)NCBI
mRatBN7.2195,902,014 - 95,914,834 (-)NCBI
RefSeq Acc Id: XM_063284212   ⟹   XP_063140282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,038,487 - 105,051,307 (-)NCBI
RefSeq Acc Id: XM_063284219   ⟹   XP_063140289
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,038,487 - 105,051,851 (-)NCBI
RefSeq Acc Id: NP_001020576   ⟸   NM_001025405
- UniProtKB: A6JB30 (UniProtKB/TrEMBL),   Q4QQS4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000028217   ⟸   ENSRNOT00000028217
RefSeq Acc Id: XP_038960974   ⟸   XM_039105046
- Peptide Label: isoform X3
- UniProtKB: G3V8T5 (UniProtKB/TrEMBL),   Q4QQS4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079618   ⟸   ENSRNOT00000097056
Ensembl Acc Id: ENSRNOP00000088524   ⟸   ENSRNOT00000111472
RefSeq Acc Id: XP_063140289   ⟸   XM_063284219
- Peptide Label: isoform X2
- UniProtKB: Q4QQS4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140282   ⟸   XM_063284212
- Peptide Label: isoform X1
- UniProtKB: Q4QQS4 (UniProtKB/TrEMBL)
Protein Domains
AAA+ ATPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V8T5-F1-model_v2 AlphaFold G3V8T5 1-463 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690039
Promoter ID:EPDNEW_R563
Type:multiple initiation site
Name:Ruvbl2_1
Description:RuvB-like AAA ATPase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01101,426,638 - 101,426,698EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306509 AgrOrtholog
BioCyc Gene G2FUF-59685 BioCyc
Ensembl Genes ENSRNOG00000020793 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028217.7 UniProtKB/TrEMBL
  ENSRNOT00000097056.1 UniProtKB/TrEMBL
  ENSRNOT00000111472.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  2.40.50.360 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7129720 IMAGE-MGC_LOAD
  IMAGE:7457010 IMAGE-MGC_LOAD
InterPro ATPase_AAA+_core UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RuvB-like UniProtKB/TrEMBL
  RuvB-like_C UniProtKB/TrEMBL
  RUVBL2_DII UniProtKB/TrEMBL
  TIP49_C UniProtKB/TrEMBL
KEGG Report rno:292907 UniProtKB/TrEMBL
MGC_CLONE MGC:116199 IMAGE-MGC_LOAD
  MGC:95150 IMAGE-MGC_LOAD
NCBI Gene 292907 ENTREZGENE
PANTHER PTHR11093 UniProtKB/TrEMBL
  PTHR11093:SF2 UniProtKB/TrEMBL
Pfam TIP49 UniProtKB/TrEMBL
  TIP49_C UniProtKB/TrEMBL
PharmGKB RUVBL2 RGD
PhenoGen Ruvbl2 PhenoGen
PRINTS DNAREPAIRADA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020793 RatGTEx
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I5ZNN3_RAT UniProtKB/TrEMBL
  A0A8I6AAZ0_RAT UniProtKB/TrEMBL
  A6JB30 ENTREZGENE, UniProtKB/TrEMBL
  G3V8T5 ENTREZGENE, UniProtKB/TrEMBL
  Q4QQS4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-09-18 Ruvbl2  RuvB-like AAA ATPase 2  Ruvbl2  RuvB-like 2 (E. coli)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Ruvbl2  RuvB-like 2 (E. coli)  Ruvbl2  RuvB-like protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Ruvbl2  RuvB-like protein 2  Ruvbl2  RuvB-like 2 (E. coli)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ruvbl2  RuvB-like 2 (E. coli)  Ruvbl2_predicted  RuvB-like 2 (E. coli) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ruvbl2_predicted  RuvB-like 2 (E. coli) (predicted)      Symbol and Name status set to approved 70820 APPROVED