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Gene: Cyth2 (cytohesin 2) Rattus norvegicus
Symbol: Cyth2
Name: cytohesin 2
RGD ID: 620398
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity and inositol 1,4,5 trisphosphate binding activity. Involved in negative regulation of dendrite development. Localizes to ruffle. Orthologous to human CYTH2 (cytohesin 2); PARTICIPATES IN Arf family mediated signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ARF nucleotide binding site opener; ARF nucleotide-binding site opener; Arno; CLM2; cytohesin-2; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled/coil domains 2; Pscd2; Sec7; SEC7 homolog B; Sec7B
Homo sapiens (human) : CYTH2 (cytohesin 2)  HGNC  Alliance
Mus musculus (house mouse) : Cyth2 (cytohesin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cyth2 (cytohesin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CYTH2 (cytohesin 2)
Canis lupus familiaris (dog) : CYTH2 (cytohesin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cyth2 (cytohesin 2)
Sus scrofa (pig) : CYTH2 (cytohesin 2)
Chlorocebus sabaeus (African green monkey) : CYTH2 (cytohesin 2)
Heterocephalus glaber (naked mole-rat) : Cyth2 (cytohesin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01101,796,349 - 101,803,407 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,796,349 - 101,803,200 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,875,334 - 102,882,766 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,284,658 - 96,291,450 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1196,362,775 - 96,369,565 (-)NCBI
Celera190,536,747 - 90,543,596 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cyth2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620398
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.