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Gene: Cyth2 (cytohesin 2) Rattus norvegicus
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Symbol: Cyth2
Name: cytohesin 2
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity and inositol 1,4,5 trisphosphate binding activity. Involved in negative regulation of dendrite development. Localizes to the extrinsic component of postsynaptic specialization membrane and ruffle. Orthologous to human CYTH2 (cytohesin 2); PARTICIPATES IN Arf family mediated signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ARF nucleotide binding site opener; ARF nucleotide-binding site opener; Arno; CLM2; cytohesin-2; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled/coil domains 2; Pscd2; Sec7; SEC7 homolog B; Sec7B
Orthologs:
Homo sapiens (human) : CYTH2 (cytohesin 2)  HGNC  Alliance
Mus musculus (house mouse) : Cyth2 (cytohesin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cyth2 (cytohesin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CYTH2 (cytohesin 2)
Canis lupus familiaris (dog) : CYTH2 (cytohesin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cyth2 (cytohesin 2)
Sus scrofa (pig) : CYTH2 (cytohesin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01101,796,349 - 101,803,407 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01102,875,334 - 102,882,766 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,284,658 - 96,291,450 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1196,362,775 - 96,369,565 (-)NCBI
Celera190,536,747 - 90,543,596 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyth2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620398
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-06-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.