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Gene: Cckbr (cholecystokinin B receptor) Rattus norvegicus
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Symbol: Cckbr
Name: cholecystokinin B receptor
Description: Exhibits gastrin receptor activity. Involved in several processes, including ERK1 and ERK2 cascade; estrous cycle; and positive regulation of cell communication. Localizes to the cytoplasm; nucleus; and plasma membrane. Used to study colitis and pancreatic cancer. Biomarker of pancreatic cancer and toxic shock syndrome. Human ortholog(s) of this gene implicated in pancreatic cancer and panic disorder. Orthologous to human CCKBR (cholecystokinin B receptor); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; INTERACTS WITH (+)-catechin; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CCK(B) receptor; CCK-B receptor; CCK-BR; CCK2 receptor; CCK2-R; Cck2r; cholecystokinin-2 receptor; CHOLREC; gastrin/cholecystokinin type B receptor
Orthologs:
Homo sapiens (human) : CCKBR (cholecystokinin B receptor)  HGNC  Alliance
Mus musculus (house mouse) : Cckbr (cholecystokinin B receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cckbr (cholecystokinin B receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : CCKBR (cholecystokinin B receptor)
Canis lupus familiaris (dog) : CCKBR (cholecystokinin B receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cckbr (cholecystokinin B receptor)
Sus scrofa (pig) : CCKBR (cholecystokinin B receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01170,262,218 - 170,272,298 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01177,269,044 - 177,279,480 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41163,156,914 - 163,166,969 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11163,252,390 - 163,262,446 (+)NCBI
Celera1157,706,263 - 157,716,114 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cckbr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2290
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.