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Gene: Cish (cytokine inducible SH2-containing protein) Rattus norvegicus
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Symbol: Cish
Name: cytokine inducible SH2-containing protein
Description: Predicted to have 1-phosphatidylinositol-3-kinase regulator activity. Involved in cytokine-mediated signaling pathway. Predicted to localize to the phosphatidylinositol 3-kinase complex and plasma membrane. Human ortholog(s) of this gene implicated in malaria and tuberculosis. Orthologous to human CISH (cytokine inducible SH2 containing protein); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; interleukin-2 signaling pathway; interleukin-3 signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cis; CIS-1; cytokine inducible SH2-containing protein 1; cytokine-inducible SH2-containing protein; SOCS; suppressor of cytokine signaling
Orthologs:
Homo sapiens (human) : CISH (cytokine inducible SH2 containing protein)  HGNC  Alliance
Mus musculus (house mouse) : Cish (cytokine inducible SH2-containing protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cish (cytokine inducible SH2 containing protein)
Pan paniscus (bonobo/pygmy chimpanzee) : CISH (cytokine inducible SH2 containing protein)
Canis lupus familiaris (dog) : CISH (cytokine inducible SH2 containing protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cish (cytokine inducible SH2 containing protein)
Sus scrofa (pig) : CISH (cytokine inducible SH2 containing protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08116,054,547 - 116,059,494 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,054,465 - 116,060,723 (+)Ensembl
Rnor_5.08115,411,027 - 115,415,974 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48112,541,034 - 112,545,982 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18112,560,606 - 112,564,500 (+)NCBI
Celera8107,282,095 - 107,287,043 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cish
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69261
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.