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Gene: Tpm3 (tropomyosin 3) Rattus norvegicus
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Symbol: Tpm3
Name: tropomyosin 3
Description: Predicted to have actin filament binding activity. Involved in brain development. Localizes to the brush border. Predicted to colocalize with the cleavage furrow. Human ortholog(s) of this gene implicated in nemaline myopathy 1. Orthologous to human TPM3 (tropomyosin 3); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; thyroid cancer pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: gamma-tropomyosin; nonmuscle tropomyosin 5; TM30nm; Tpm5; tropomyosin 3, gamma; tropomyosin alpha-3 chain; tropomyosin non-muscle; tropomyosin-3; tropomyosin-5
Orthologs:
Homo sapiens (human) : TPM3 (tropomyosin 3)  HGNC  Alliance
Mus musculus (house mouse) : Tpm3 (tropomyosin 3, gamma)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tpm3 (tropomyosin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TPM3 (tropomyosin 3)
Canis lupus familiaris (dog) : TPM3 (tropomyosin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tpm3 (tropomyosin 3)
Sus scrofa (pig) : TPM3 (tropomyosin 3)
more info ...
Allele / Splice: Tpm3_v1   Tpm3_v3   Tpm3_v2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02189,423,534 - 189,451,340 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02208,856,598 - 208,884,385 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,303,994 - 182,324,994 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12182,254,141 - 182,273,295 (+)NCBI
Celera2169,456,120 - 169,483,632 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tpm3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621546
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.