Cabin1 (calcineurin binding protein 1) - Rat Genome Database

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Gene: Cabin1 (calcineurin binding protein 1) Rattus norvegicus
Analyze
Symbol: Cabin1
Name: calcineurin binding protein 1
RGD ID: 620263
Description: Enables protein domain specific binding activity and protein phosphatase 2B binding activity. Involved in negative regulation of apoptotic process and response to activity. Predicted to be located in aggresome; cytosol; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in ovarian carcinoma. Orthologous to human CABIN1 (calcineurin binding protein 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cain; calcineurin inhibitor; calcineurin-binding protein cabin-1; calcineurin-binding protein cabin-1-like; LOC103689948
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82012,892,750 - 13,014,801 (+)NCBIGRCr8
mRatBN7.22012,893,314 - 13,015,357 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2012,893,358 - 13,015,357 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2013,599,937 - 13,721,941 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02012,960,879 - 13,082,888 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,432,984 - 13,555,133 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02013,836,032 - 13,963,003 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,836,030 - 13,963,003 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02016,025,717 - 16,151,225 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02015,924,052 - 15,942,759 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,444,801 - 13,569,453 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12013,445,046 - 13,569,680 (-)NCBI
Celera2014,383,605 - 14,503,982 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
aggresome  (IEA,ISO)
cytoplasm  (IEA)
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. DNA hypermethylation, Her-2/neu overexpression and p53 mutations in ovarian carcinoma. Feng Q, etal., Gynecol Oncol. 2008 Nov;111(2):320-9. doi: 10.1016/j.ygyno.2008.07.036. Epub 2008 Aug 30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Gene expression profiling of exercise-induced cardiac hypertrophy in rats. Iemitsu M, etal., Acta Physiol Scand. 2005 Dec;185(4):259-70.
4. Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death. Kim MJ, etal., Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9870-5.
5. Cain, a novel physiologic protein inhibitor of calcineurin. Lai MM, etal., J Biol Chem 1998 Jul 17;273(29):18325-31.
6. The calcineurin-binding protein cain is a negative regulator of synaptic vesicle endocytosis. Lai MM, etal., J Biol Chem. 2000 Nov 3;275(44):34017-20.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214. van Deursen J, etal., EMBO J 1996 Oct 15;15(20):5574-83.
14. Regulation of inflammatory responses and fibroblast-like synoviocyte apoptosis by calcineurin-binding protein 1 in mice with collagen-induced arthritis. Yi JK, etal., Arthritis Rheum. 2012 Jul;64(7):2191-200. doi: 10.1002/art.34398.
Additional References at PubMed
PMID:14718166   PMID:26400065   PMID:29190603   PMID:29368245   PMID:32000560  


Genomics

Comparative Map Data
Cabin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82012,892,750 - 13,014,801 (+)NCBIGRCr8
mRatBN7.22012,893,314 - 13,015,357 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2012,893,358 - 13,015,357 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2013,599,937 - 13,721,941 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02012,960,879 - 13,082,888 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,432,984 - 13,555,133 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02013,836,032 - 13,963,003 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,836,030 - 13,963,003 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02016,025,717 - 16,151,225 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02015,924,052 - 15,942,759 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,444,801 - 13,569,453 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12013,445,046 - 13,569,680 (-)NCBI
Celera2014,383,605 - 14,503,982 (+)NCBICelera
Cytogenetic Map20p12NCBI
CABIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382224,011,304 - 24,178,628 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2224,011,192 - 24,178,628 (+)EnsemblGRCh38hg38GRCh38
GRCh372224,407,754 - 24,574,596 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,737,765 - 22,904,596 (+)NCBINCBI36Build 36hg18NCBI36
Build 342222,732,318 - 22,899,150NCBI
Celera228,207,658 - 8,374,995 (+)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef227,355,977 - 7,523,706 (+)NCBIHuRef
CHM1_12224,366,024 - 24,533,337 (+)NCBICHM1_1
T2T-CHM13v2.02224,472,930 - 24,640,242 (+)NCBIT2T-CHM13v2.0
Cabin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391075,481,944 - 75,600,194 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1075,481,946 - 75,600,175 (-)EnsemblGRCm39 Ensembl
GRCm381075,646,110 - 75,764,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,646,112 - 75,764,341 (-)EnsemblGRCm38mm10GRCm38
MGSCv371075,108,855 - 75,227,102 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361075,089,828 - 75,208,073 (-)NCBIMGSCv36mm8
Celera1076,690,803 - 76,809,131 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.56NCBI
Cabin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554558,162,315 - 8,312,909 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554558,162,365 - 8,312,932 (-)NCBIChiLan1.0ChiLan1.0
CABIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22333,795,295 - 33,963,647 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12236,529,019 - 36,697,375 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0224,816,411 - 4,984,760 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12222,902,776 - 23,070,598 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2222,927,572 - 23,070,165 (+)Ensemblpanpan1.1panPan2
CABIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12628,366,264 - 28,517,570 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2628,366,265 - 28,517,656 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2627,440,625 - 27,591,723 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02629,770,268 - 29,921,946 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2629,770,270 - 29,921,917 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12627,854,246 - 28,005,988 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02627,470,762 - 27,622,599 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02628,460,896 - 28,611,816 (-)NCBIUU_Cfam_GSD_1.0
Cabin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118141,723,046 - 141,863,600 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936619890,299 - 1,030,899 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936619890,474 - 1,030,914 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CABIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,686,196 - 49,787,688 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11449,686,196 - 49,787,723 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,128,158 - 53,229,937 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CABIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1197,127,370 - 7,289,054 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl197,127,401 - 7,289,050 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366610073,032 - 234,603 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cabin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474710,110,370 - 10,257,276 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474710,110,476 - 10,257,165 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cabin1
449 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:55
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000001659
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20669170617489458Rat
1581577Pur15Proteinuria QTL 154.380.0002urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804241017617956Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
631265Iresp1Immunoglobin response QTL18.3blood anti-double stranded DNA antibody amount (VT:0004762)serum anti-DNA antibody level (CMO:0001533)20903971913461775Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat

Markers in Region
BF390741  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22012,984,027 - 12,984,193 (+)MAPPERmRatBN7.2
Rnor_6.02013,931,680 - 13,931,845NCBIRnor6.0
Rnor_5.02016,119,902 - 16,120,067UniSTSRnor5.0
RGSC_v3.42013,475,960 - 13,476,125UniSTSRGSC3.4
Celera2014,472,769 - 14,472,934UniSTS
Cytogenetic Map20p12UniSTS
RH128071  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22013,015,044 - 13,015,247 (+)MAPPERmRatBN7.2
Rnor_6.02013,962,691 - 13,962,893NCBIRnor6.0
Rnor_5.02016,150,913 - 16,151,115UniSTSRnor5.0
RGSC_v3.42013,444,911 - 13,445,113UniSTSRGSC3.4
Celera2014,503,670 - 14,503,872UniSTS
RH 3.4 Map20154.36UniSTS
Cytogenetic Map20p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 22 21 12 14 12 74 25 40 11
Low 2 21 36 29 5 29 8 11 10 1 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000001659   ⟹   ENSRNOP00000001659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2012,993,393 - 13,015,356 (+)Ensembl
Rnor_6.0 Ensembl2013,836,030 - 13,963,003 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093157   ⟹   ENSRNOP00000076295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2012,893,358 - 13,015,357 (+)Ensembl
Rnor_6.0 Ensembl2013,836,030 - 13,963,003 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2013,955,670 - 13,962,098 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093587   ⟹   ENSRNOP00000076268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2013,940,877 - 13,951,820 (+)Ensembl
RefSeq Acc Id: NM_053575   ⟹   NP_446027
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,892,793 - 13,014,801 (+)NCBI
mRatBN7.22012,893,360 - 13,015,357 (+)NCBI
Rnor_6.02013,836,032 - 13,963,003 (+)NCBI
Rnor_5.02016,025,717 - 16,151,225 (+)NCBI
RGSC_v3.42013,444,801 - 13,569,453 (-)RGD
Celera2014,383,605 - 14,503,982 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099130   ⟹   XP_038955058
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,892,755 - 13,014,800 (+)NCBI
mRatBN7.22012,893,317 - 13,015,357 (+)NCBI
RefSeq Acc Id: XM_039099132   ⟹   XP_038955060
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,892,750 - 12,943,625 (+)NCBI
mRatBN7.22012,893,314 - 12,944,192 (+)NCBI
RefSeq Acc Id: XM_063279580   ⟹   XP_063135650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,892,751 - 12,967,072 (+)NCBI
RefSeq Acc Id: XR_005497345
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,892,751 - 12,961,755 (+)NCBI
mRatBN7.22012,893,314 - 12,962,303 (+)NCBI
RefSeq Acc Id: NP_446027   ⟸   NM_053575
- UniProtKB: O88480 (UniProtKB/Swiss-Prot),   A0A1W2Q6J1 (UniProtKB/TrEMBL),   A6JKH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000076268   ⟸   ENSRNOT00000093587
RefSeq Acc Id: ENSRNOP00000076295   ⟸   ENSRNOT00000093157
RefSeq Acc Id: ENSRNOP00000001659   ⟸   ENSRNOT00000001659
RefSeq Acc Id: XP_038955060   ⟸   XM_039099132
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038955058   ⟸   XM_039099130
- Peptide Label: isoform X1
- UniProtKB: O88480 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063135650   ⟸   XM_063279580
- Peptide Label: isoform X2
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88480-F1-model_v2 AlphaFold O88480 1-2182 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701536
Promoter ID:EPDNEW_R12060
Type:initiation region
Name:Cabin1_2
Description:calcineurin binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R12061  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02013,836,000 - 13,836,060EPDNEW
RGD ID:13701537
Promoter ID:EPDNEW_R12061
Type:multiple initiation site
Name:Cabin1_1
Description:calcineurin binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R12060  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02013,941,109 - 13,941,169EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620263 AgrOrtholog
BioCyc Gene G2FUF-4156 BioCyc
Ensembl Genes ENSRNOG00000001237 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00065026458 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001659.6 UniProtKB/TrEMBL
  ENSRNOT00000093157 ENTREZGENE
  ENSRNOT00000093157.2 UniProtKB/TrEMBL
  ENSRNOT00065045776 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Hir3/CABIN1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MEF2-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94165 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 94165 ENTREZGENE
PANTHER CALCINEURIN-BINDING PROTEIN CABIN-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15502 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MEF2_binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cabin1 PhenoGen
PROSITE TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001237 RatGTEx
  ENSRNOG00065026458 RatGTEx
SMART TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1W2Q6J1 ENTREZGENE, UniProtKB/TrEMBL
  A6JKH7 ENTREZGENE, UniProtKB/TrEMBL
  A6JKH8_RAT UniProtKB/TrEMBL
  A6JKI0_RAT UniProtKB/TrEMBL
  CABIN_RAT UniProtKB/Swiss-Prot
  G3V650_RAT UniProtKB/TrEMBL
  O88480 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Cabin1  calcineurin binding protein 1  LOC103689948  calcineurin-binding protein cabin-1-like  Data merged from RGD:9130189 737654 PROVISIONAL
2014-08-25 LOC103689948  calcineurin-binding protein cabin-1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-12-07 Cabin1  calcineurin binding protein 1  Cain  cain  Symbol and Name updated 1299863 APPROVED
2002-08-07 Cain  cain      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression predominantly expressed in neuronal tissues 632368
gene_protein 240-kDa 632368