Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Dis3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease) Rattus norvegicus
Analyze
Symbol: Dis3
Name: DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
Description: Predicted to have 3'-5'-exoribonuclease activity; endonuclease activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in CUT catabolic process and rRNA catabolic process. Predicted to localize to the cytoplasmic exosome (RNase complex); cytosol; and nuclear lumen. Orthologous to human DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease); PARTICIPATES IN ribosome biogenesis pathway; RNA degradation pathway; INTERACTS WITH methamphetamine; tetrachloromethane; thioacetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; DIS3 mitotic control; DIS3 mitotic control homolog; DIS3 mitotic control homolog (S. cerevisiae); exosome complex exonuclease RRP44; LOC306103; RGD1304646; similar to mitotic control protein dis3 homolog
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01583,466,330 - 83,494,107 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1583,466,428 - 83,494,423 (-)Ensembl
Rnor_5.01586,975,865 - 87,005,393 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41582,855,389 - 82,881,767 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11582,871,188 - 82,897,665 (-)NCBI
Celera1575,064,436 - 75,090,827 (-)NCBICelera
Cytogenetic Map15q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dis3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304646
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.