Mitf (melanocyte inducing transcription factor) - Rat Genome Database

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Gene: Mitf (melanocyte inducing transcription factor) Rattus norvegicus
Analyze
Symbol: Mitf
Name: melanocyte inducing transcription factor
RGD ID: 3092
Description: Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; E-box binding activity; and protein dimerization activity. Involved in transcription, DNA-templated. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Tietz syndrome; Tietze's syndrome; Waardenburg syndrome type 2A; Waardenburg's syndrome; and familial melanoma. Orthologous to human MITF (melanocyte inducing transcription factor); PARTICIPATES IN interleukin-6 signaling pathway; melanoma pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: melanogenesis associated transcription factor; microphthalmia-associated transcription factor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24130,409,020 - 130,621,145 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl4130,409,217 - 130,621,145 (+)Ensembl
Rnor_6.04130,172,484 - 130,425,496 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4130,172,727 - 130,425,532 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04194,667,943 - 194,921,498 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44132,534,187 - 132,745,669 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14132,971,000 - 132,989,691 (+)NCBI
Celera4119,282,401 - 119,497,938 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinic acid  (ISO)
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
9-cis-retinal  (ISO)
9-cis-retinoic acid  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
afzelin  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
aristolochic acid  (ISO)
arsenite(3-)  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbaryl  (ISO)
carbon nanotube  (ISO)
chaetocin  (ISO)
chlorpromazine  (ISO)
ciguatoxin CTX1B  (ISO)
ciprofloxacin  (ISO)
cisplatin  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cyanamide  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
DDT  (EXP)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
emodin  (ISO)
entinostat  (ISO)
fenofibrate  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
ivermectin  (ISO)
lawsone  (ISO)
lead diacetate  (ISO)
lithium chloride  (ISO)
LY294002  (ISO)
melphalan  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methylseleninic acid  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-phenylthiourea  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nonanedioic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
permethrin  (EXP)
phenylmercury acetate  (ISO)
phytol  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
Ptaquiloside  (ISO)
quercetin  (ISO)
resorcinol  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
stilbenoid  (ISO)
Sweroside  (ISO)
tamoxifen  (ISO)
taurine  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
theophylline  (ISO)
thioacetamide  (EXP)
thymol  (ISO)
thymol sulfate(1-)  (ISO)
torcetrapib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vemurafenib  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cellular_component  (ND)
cytoplasm  (IEA,ISO,ISS)
nucleus  (IBA,IEA,ISO,ISS)
protein-containing complex  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:2379821   PMID:8995290   PMID:9199364   PMID:9647758   PMID:11930005   PMID:12086670   PMID:12204775   PMID:12235125   PMID:14575687   PMID:14737107   PMID:15304486   PMID:15576400  
PMID:15716956   PMID:15729346   PMID:16411896   PMID:17442941   PMID:19188590   PMID:19201870   PMID:20530484   PMID:21209915   PMID:22234890   PMID:22523078   PMID:23207919   PMID:23980096  
PMID:24769727   PMID:26388265   PMID:27889061  


Genomics

Comparative Map Data
Mitf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24130,409,020 - 130,621,145 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl4130,409,217 - 130,621,145 (+)Ensembl
Rnor_6.04130,172,484 - 130,425,496 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4130,172,727 - 130,425,532 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04194,667,943 - 194,921,498 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44132,534,187 - 132,745,669 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14132,971,000 - 132,989,691 (+)NCBI
Celera4119,282,401 - 119,497,938 (+)NCBICelera
Cytogenetic Map4q34NCBI
MITF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38369,739,464 - 69,968,332 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl369,739,456 - 69,968,336 (+)EnsemblGRCh38hg38GRCh38
GRCh37369,788,615 - 70,017,483 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36369,871,323 - 70,100,177 (+)NCBINCBI36hg18NCBI36
Build 34370,010,945 - 70,100,176NCBI
Celera369,715,972 - 69,944,858 (+)NCBI
Cytogenetic Map3p13NCBI
HuRef369,788,411 - 70,016,737 (+)NCBIHuRef
CHM1_1369,739,823 - 69,968,702 (+)NCBICHM1_1
Mitf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39697,783,966 - 97,998,321 (+)NCBIGRCm39mm39
GRCm39 Ensembl697,784,013 - 97,998,310 (+)Ensembl
GRCm38697,807,002 - 98,021,360 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl697,807,052 - 98,021,349 (+)EnsemblGRCm38mm10GRCm38
MGSCv37697,757,052 - 97,971,352 (+)NCBIGRCm37mm9NCBIm37
MGSCv36697,957,255 - 97,984,170 (+)NCBImm8
Celera699,672,554 - 99,880,690 (+)NCBICelera
Cytogenetic Map6D3NCBI
cM Map645.05NCBI
Mitf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542117,947,277 - 18,154,090 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542117,948,117 - 18,157,379 (-)NCBIChiLan1.0ChiLan1.0
MITF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1371,037,671 - 71,265,445 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl371,037,665 - 71,265,445 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0369,674,064 - 69,902,078 (+)NCBIMhudiblu_PPA_v0panPan3
MITF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12021,772,147 - 21,873,545 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2021,612,927 - 21,870,578 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2021,826,585 - 21,857,697 (-)NCBI
ROS_Cfam_1.02021,883,312 - 22,101,930 (-)NCBI
ROS_Cfam_1.0 Ensembl2021,886,050 - 22,101,945 (-)Ensembl
UMICH_Zoey_3.12021,572,611 - 21,603,715 (-)NCBI
UNSW_CanFamBas_1.02021,921,161 - 21,952,266 (-)NCBI
UU_Cfam_GSD_1.02021,991,588 - 22,022,704 (-)NCBI
Mitf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049421,682,409 - 1,858,295 (+)NCBI
SpeTri2.0NW_0049366031,682,411 - 1,858,295 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MITF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1351,178,203 - 51,422,096 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11351,177,356 - 51,422,096 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21356,593,519 - 56,594,255 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MITF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12230,747,747 - 30,971,951 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2230,748,440 - 30,972,168 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041135,815,967 - 136,039,769 (-)NCBIVero_WHO_p1.0
Mitf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247734,346,072 - 4,561,218 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D4Rat116  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,492,986 - 130,493,224 (+)MAPPERmRatBN7.2
Rnor_6.04130,297,677 - 130,297,914NCBIRnor6.0
Rnor_5.04194,793,679 - 194,793,916UniSTSRnor5.0
RGSC_v3.44132,619,018 - 132,619,344RGDRGSC3.4
RGSC_v3.44132,619,103 - 132,619,340UniSTSRGSC3.4
RGSC_v3.14132,863,944 - 132,864,181RGD
Celera4119,365,717 - 119,365,954UniSTS
RH 3.4 Map4805.7RGD
RH 3.4 Map4805.7UniSTS
RH 2.0 Map4867.2RGD
SHRSP x BN Map456.66RGD
FHH x ACI Map477.9799RGD
Cytogenetic Map4q34-q41UniSTS
D4Got97  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.04194,882,127 - 194,882,230NCBIRnor5.0
Rnor_5.04194,882,126 - 194,882,230NCBIRnor5.0
Rnor_5.04194,882,087 - 194,882,230NCBIRnor5.0
Rnor_5.04194,882,086 - 194,882,230NCBIRnor5.0
RGSC_v3.44132,709,021 - 132,709,164RGDRGSC3.4
RGSC_v3.44132,709,022 - 132,709,164UniSTSRGSC3.4
RGSC_v3.44132,709,062 - 132,709,164UniSTSRGSC3.4
RGSC_v3.44132,709,061 - 132,709,164RGDRGSC3.4
RGSC_v3.14132,953,863 - 132,954,005RGD
Celera4119,458,562 - 119,458,656UniSTS
RH 3.4 Map4795.01RGD
RH 3.4 Map4795.01UniSTS
Cytogenetic Map4q34-q41UniSTS
Mitf  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,538,293 - 130,538,433 (+)MAPPERmRatBN7.2
Rnor_6.04130,342,654 - 130,342,793NCBIRnor6.0
Rnor_5.04194,838,656 - 194,838,795UniSTSRnor5.0
RGSC_v3.44132,665,646 - 132,665,785UniSTSRGSC3.4
Celera4119,410,997 - 119,411,136UniSTS
Cytogenetic Map4q34-q41UniSTS
BE097660  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,453,838 - 130,453,996 (+)MAPPERmRatBN7.2
Rnor_6.04130,217,446 - 130,217,603NCBIRnor6.0
Rnor_5.04194,712,765 - 194,712,922UniSTSRnor5.0
RGSC_v3.44132,579,691 - 132,579,848UniSTSRGSC3.4
Celera4119,326,747 - 119,326,904UniSTS
RH 3.4 Map4805.3UniSTS
Cytogenetic Map4q34-q41UniSTS
AU048069  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,561,057 - 130,561,191 (+)MAPPERmRatBN7.2
Rnor_6.04130,365,409 - 130,365,542NCBIRnor6.0
Rnor_5.04194,861,411 - 194,861,544UniSTSRnor5.0
RGSC_v3.44132,688,401 - 132,688,534UniSTSRGSC3.4
Celera4119,433,721 - 119,433,854UniSTS
Cytogenetic Map4q34-q41UniSTS
RH139322  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,489,447 - 130,489,587 (+)MAPPERmRatBN7.2
Rnor_6.04130,294,138 - 130,294,277NCBIRnor6.0
Rnor_5.04194,790,140 - 194,790,279UniSTSRnor5.0
RGSC_v3.44132,615,564 - 132,615,703UniSTSRGSC3.4
Celera4119,362,176 - 119,362,315UniSTS
RH 3.4 Map1850.2UniSTS
Cytogenetic Map4q34-q41UniSTS
UniSTS:496619  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,586,060 - 130,587,341 (+)MAPPERmRatBN7.2
Rnor_6.04130,390,412 - 130,391,692NCBIRnor6.0
Rnor_5.04194,886,414 - 194,887,694UniSTSRnor5.0
RGSC_v3.44132,713,348 - 132,714,628UniSTSRGSC3.4
Celera4119,462,844 - 119,464,124UniSTS
Cytogenetic Map4q34-q41UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4120926564148090731Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4120260281147278687Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4105789505150789505Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106649412151649412Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4116179486151161268Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109827074154827074Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)4106805662151805662Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109827074154827074Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4119463257147278687Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir182rno-miR-182Mirtarbaseexternal_infoWestern blotFunctional MTI19167416
Mir96rno-miR-96-5pMirtarbaseexternal_infoWestern blotFunctional MTI19167416

Predicted Target Of
Summary Value
Count of predictions:204
Count of miRNA genes:140
Interacting mature miRNAs:164
Transcripts:ENSRNOT00000051121
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 42 23 6 2
Low 3 1 57 41 19 41 8 11 74 12 32 9 8
Below cutoff 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000051121   ⟹   ENSRNOP00000044350
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4130,409,217 - 130,621,145 (+)Ensembl
Rnor_6.0 Ensembl4130,172,727 - 130,422,735 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083127   ⟹   ENSRNOP00000073565
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4130,527,867 - 130,621,145 (+)Ensembl
Rnor_6.0 Ensembl4130,332,076 - 130,425,532 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094478   ⟹   ENSRNOP00000084182
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4130,584,902 - 130,621,145 (+)Ensembl
RefSeq Acc Id: NM_001191089   ⟹   NP_001178018
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,217 - 130,621,145 (+)NCBI
Rnor_6.04130,172,856 - 130,425,496 (+)NCBI
Rnor_5.04194,667,943 - 194,921,498 (+)NCBI
Celera4119,282,401 - 119,497,938 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592477   ⟹   XP_017447966
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,024 - 130,621,145 (+)NCBI
Rnor_6.04130,172,484 - 130,425,496 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592478   ⟹   XP_017447967
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,526,535 - 130,617,941 (+)NCBI
Rnor_6.04130,332,222 - 130,425,496 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107083   ⟹   XP_038963011
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,020 - 130,617,941 (+)NCBI
RefSeq Acc Id: XM_039107085   ⟹   XP_038963013
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,217 - 130,617,941 (+)NCBI
RefSeq Acc Id: XM_039107086   ⟹   XP_038963014
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,526,535 - 130,617,941 (+)NCBI
RefSeq Acc Id: XM_039107087   ⟹   XP_038963015
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,427,689 - 130,617,941 (+)NCBI
RefSeq Acc Id: XM_039107088   ⟹   XP_038963016
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,284 - 130,617,941 (+)NCBI
RefSeq Acc Id: XM_039107089   ⟹   XP_038963017
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,024 - 130,621,145 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001178018   ⟸   NM_001191089
- UniProtKB: O88368 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017447966   ⟸   XM_017592477
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017447967   ⟸   XM_017592478
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K5U8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000044350   ⟸   ENSRNOT00000051121
RefSeq Acc Id: ENSRNOP00000073565   ⟸   ENSRNOT00000083127
RefSeq Acc Id: XP_038963011   ⟸   XM_039107083
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038963017   ⟸   XM_039107089
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038963013   ⟸   XM_039107085
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963016   ⟸   XM_039107088
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038963015   ⟸   XM_039107087
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038963014   ⟸   XM_039107086
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000084182   ⟸   ENSRNOT00000094478
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88368-F1-model_v2 AlphaFold O88368 1-526 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693271
Promoter ID:EPDNEW_R3796
Type:single initiation site
Name:Mitf_1
Description:melanogenesis associated transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04130,172,727 - 130,172,787EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3092 AgrOrtholog
BioCyc Gene G2FUF-43595 BioCyc
Ensembl Genes ENSRNOG00000008658 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000044350 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000073565 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000051121 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000083127 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MiT/TFE_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MiT/TFE_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MITF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25094 UniProtKB/Swiss-Prot
NCBI Gene 25094 ENTREZGENE
PANTHER PTHR45776:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF3371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MITF_TFEB_C_3_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mitf PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K5U8 ENTREZGENE, UniProtKB/TrEMBL
  MITF_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary F1LQV3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-10-16 Mitf  melanocyte inducing transcription factor  Mitf  melanogenesis associated transcription factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-06-02 Mitf  melanogenesis associated transcription factor  Mitf  microphthalmia-associated transcription factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Mitf  Microphthalmia-associated transcription factor      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease deletion in gene may be associated with osteopetrosis 729082
gene_process may be involved in pigmentation, mast cells, and bone development 729082