Mitf (melanocyte inducing transcription factor) - Rat Genome Database

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Gene: Mitf (melanocyte inducing transcription factor) Rattus norvegicus
Analyze
Symbol: Mitf
Name: melanocyte inducing transcription factor
RGD ID: 3092
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; E-box binding activity; and protein dimerization activity. Involved in transcription, DNA-templated. Predicted to localize to cytoplasm; nucleus; and protein-containing complex. Human ortholog(s) of this gene implicated in Tietz syndrome; Tietze's syndrome; Waardenburg syndrome type 2A; Waardenburg's syndrome; and familial melanoma. Orthologous to human MITF (melanocyte inducing transcription factor); PARTICIPATES IN interleukin-6 signaling pathway; melanoma pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: melanogenesis associated transcription factor; microphthalmia-associated transcription factor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24130,409,020 - 130,621,145 (+)NCBI
Rnor_6.0 Ensembl4130,172,727 - 130,425,532 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04130,172,484 - 130,425,496 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04194,667,943 - 194,921,498 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44132,534,187 - 132,745,669 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14132,971,000 - 132,989,691 (+)NCBI
Celera4119,282,401 - 119,497,938 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinic acid  (ISO)
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
9-cis-retinal  (ISO)
9-cis-retinoic acid  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
afzelin  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
aristolochic acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbaryl  (ISO)
carbon nanotube  (ISO)
chaetocin  (ISO)
chlorpromazine  (ISO)
ciguatoxin CTX1B  (ISO)
ciprofloxacin  (ISO)
cisplatin  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cyanamide  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
DDT  (EXP)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
emodin  (ISO)
entinostat  (ISO)
fenofibrate  (ISO)
formaldehyde  (ISO)
lawsone  (ISO)
lead diacetate  (ISO)
lithium chloride  (ISO)
LY294002  (ISO)
melphalan  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methylseleninic acid  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-phenylthiourea  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nonanedioic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
phenylmercury acetate  (ISO)
phytol  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
Ptaquiloside  (ISO)
quercetin  (ISO)
resorcinol  (ISO)
resveratrol  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
stilbenoid  (ISO)
Sweroside  (ISO)
tamoxifen  (ISO)
taurine  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
theophylline  (ISO)
thymol  (ISO)
thymol sulfate(1-)  (ISO)
torcetrapib  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vemurafenib  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cellular_component  (ND)
cytoplasm  (ISO,ISS)
nucleus  (IBA,IEA,ISO,ISS)
protein-containing complex  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:2379821   PMID:8995290   PMID:9199364   PMID:9647758   PMID:11930005   PMID:12086670   PMID:12204775   PMID:12235125   PMID:14575687   PMID:14737107   PMID:15304486   PMID:15576400  
PMID:15716956   PMID:15729346   PMID:16411896   PMID:17442941   PMID:19188590   PMID:19201870   PMID:20530484   PMID:21209915   PMID:22234890   PMID:22523078   PMID:23207919   PMID:23980096  
PMID:24769727   PMID:26388265   PMID:27889061   PMID:31408435  


Genomics

Comparative Map Data
Mitf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24130,409,020 - 130,621,145 (+)NCBI
Rnor_6.0 Ensembl4130,172,727 - 130,425,532 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04130,172,484 - 130,425,496 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04194,667,943 - 194,921,498 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44132,534,187 - 132,745,669 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14132,971,000 - 132,989,691 (+)NCBI
Celera4119,282,401 - 119,497,938 (+)NCBICelera
Cytogenetic Map4q34NCBI
MITF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl369,739,464 - 69,968,336 (+)EnsemblGRCh38hg38GRCh38
GRCh38369,739,464 - 69,968,332 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37369,788,615 - 70,017,483 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36369,871,323 - 70,100,177 (+)NCBINCBI36hg18NCBI36
Build 34370,010,945 - 70,100,176NCBI
Celera369,715,972 - 69,944,858 (+)NCBI
Cytogenetic Map3p13NCBI
HuRef369,788,411 - 70,016,737 (+)NCBIHuRef
CHM1_1369,739,823 - 69,968,702 (+)NCBICHM1_1
Mitf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39697,783,966 - 97,998,321 (+)NCBIGRCm39mm39
GRCm39 Ensembl697,784,013 - 97,998,310 (+)Ensembl
GRCm38697,807,002 - 98,021,360 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl697,807,052 - 98,021,349 (+)EnsemblGRCm38mm10GRCm38
MGSCv37697,757,052 - 97,971,352 (+)NCBIGRCm37mm9NCBIm37
MGSCv36697,957,255 - 97,984,170 (+)NCBImm8
Celera699,672,554 - 99,880,690 (+)NCBICelera
Cytogenetic Map6D3NCBI
cM Map645.05NCBI
Mitf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542117,947,277 - 18,154,090 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542117,948,117 - 18,157,379 (-)NCBIChiLan1.0ChiLan1.0
MITF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1371,037,671 - 71,265,445 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl371,037,665 - 71,265,445 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0369,674,064 - 69,902,078 (+)NCBIMhudiblu_PPA_v0panPan3
MITF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12021,772,147 - 21,873,545 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2021,612,927 - 21,870,578 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2021,826,585 - 21,857,697 (-)NCBI
ROS_Cfam_1.02021,883,312 - 22,101,930 (-)NCBI
UMICH_Zoey_3.12021,572,611 - 21,603,715 (-)NCBI
UNSW_CanFamBas_1.02021,921,161 - 21,952,266 (-)NCBI
UU_Cfam_GSD_1.02021,991,588 - 22,022,704 (-)NCBI
Mitf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049421,682,409 - 1,858,295 (+)NCBI
SpeTri2.0NW_0049366031,682,411 - 1,858,295 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MITF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1351,178,203 - 51,422,096 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11351,177,356 - 51,422,096 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21356,593,519 - 56,594,255 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MITF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12230,747,747 - 30,971,951 (+)NCBI
ChlSab1.1 Ensembl2230,748,440 - 30,972,168 (+)Ensembl
Vero_WHO_p1.0NW_023666041135,815,967 - 136,039,769 (-)NCBI
Mitf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247734,346,072 - 4,561,218 (+)NCBI

Position Markers
D4Rat116  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,492,986 - 130,493,224 (+)MAPPER
Rnor_6.04130,297,677 - 130,297,914NCBIRnor6.0
Rnor_5.04194,793,679 - 194,793,916UniSTSRnor5.0
RGSC_v3.44132,619,103 - 132,619,340UniSTSRGSC3.4
RGSC_v3.44132,619,018 - 132,619,344RGDRGSC3.4
RGSC_v3.14132,863,944 - 132,864,181RGD
Celera4119,365,717 - 119,365,954UniSTS
RH 3.4 Map4805.7RGD
RH 3.4 Map4805.7UniSTS
RH 2.0 Map4867.2RGD
SHRSP x BN Map456.66RGD
FHH x ACI Map477.9799RGD
Cytogenetic Map4q34-q41UniSTS
D4Got97  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.04194,882,127 - 194,882,230NCBIRnor5.0
Rnor_5.04194,882,126 - 194,882,230NCBIRnor5.0
Rnor_5.04194,882,087 - 194,882,230NCBIRnor5.0
Rnor_5.04194,882,086 - 194,882,230NCBIRnor5.0
RGSC_v3.44132,709,022 - 132,709,164UniSTSRGSC3.4
RGSC_v3.44132,709,061 - 132,709,164RGDRGSC3.4
RGSC_v3.44132,709,021 - 132,709,164RGDRGSC3.4
RGSC_v3.44132,709,062 - 132,709,164UniSTSRGSC3.4
RGSC_v3.14132,953,863 - 132,954,005RGD
Celera4119,458,562 - 119,458,656UniSTS
RH 3.4 Map4795.01RGD
RH 3.4 Map4795.01UniSTS
Cytogenetic Map4q34-q41UniSTS
Mitf  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,538,293 - 130,538,433 (+)MAPPER
Rnor_6.04130,342,654 - 130,342,793NCBIRnor6.0
Rnor_5.04194,838,656 - 194,838,795UniSTSRnor5.0
RGSC_v3.44132,665,646 - 132,665,785UniSTSRGSC3.4
Celera4119,410,997 - 119,411,136UniSTS
Cytogenetic Map4q34-q41UniSTS
BE097660  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,453,838 - 130,453,996 (+)MAPPER
Rnor_6.04130,217,446 - 130,217,603NCBIRnor6.0
Rnor_5.04194,712,765 - 194,712,922UniSTSRnor5.0
RGSC_v3.44132,579,691 - 132,579,848UniSTSRGSC3.4
Celera4119,326,747 - 119,326,904UniSTS
RH 3.4 Map4805.3UniSTS
Cytogenetic Map4q34-q41UniSTS
AU048069  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,561,057 - 130,561,191 (+)MAPPER
Rnor_6.04130,365,409 - 130,365,542NCBIRnor6.0
Rnor_5.04194,861,411 - 194,861,544UniSTSRnor5.0
RGSC_v3.44132,688,401 - 132,688,534UniSTSRGSC3.4
Celera4119,433,721 - 119,433,854UniSTS
Cytogenetic Map4q34-q41UniSTS
RH139322  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,489,447 - 130,489,587 (+)MAPPER
Rnor_6.04130,294,138 - 130,294,277NCBIRnor6.0
Rnor_5.04194,790,140 - 194,790,279UniSTSRnor5.0
RGSC_v3.44132,615,564 - 132,615,703UniSTSRGSC3.4
Celera4119,362,176 - 119,362,315UniSTS
RH 3.4 Map1850.2UniSTS
Cytogenetic Map4q34-q41UniSTS
UniSTS:496619  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24130,586,060 - 130,587,341 (+)MAPPER
Rnor_6.04130,390,412 - 130,391,692NCBIRnor6.0
Rnor_5.04194,886,414 - 194,887,694UniSTSRnor5.0
RGSC_v3.44132,713,348 - 132,714,628UniSTSRGSC3.4
Celera4119,462,844 - 119,464,124UniSTS
Cytogenetic Map4q34-q41UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)43043231145254791Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)47850904182171018Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)423850384169318094Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)436615599145611886Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)443414605155469929Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)443414792146942075Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)443414792146942075Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)446898276145611886Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)449906054145611886Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)455324953148360954Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)458640017154427984Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)458640017154427984Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)458640017154427984Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)463537179157286626Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470773471132455556Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473786419132455556Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)481959983152055009Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)484475257178931073Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486312589146942261Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486312589147702403Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486438317168047091Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486532519131532519Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487136446132136446Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487136446132136446Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)494414208139414208Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494893247168046938Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)499066823144066823Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4105277348150277348Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)4105682594150682594Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4105971071168047091Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106347236151347236Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4108876717169215811Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109636356154636356Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109636356154636356Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110702761155702761Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110702761155702761Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4112807675157807675Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4115372758150038284Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4116726724157291438Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4117926139162926139Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4119705414146087100Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4120318422146087100Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4120400597146942261Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4123111827168111827Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123478354168478354Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4123587009168587009Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4124442168169442168Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4125884464168047091Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4128602727173602727Rat

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir182rno-miR-182Mirtarbaseexternal_infoWestern blotFunctional MTI19167416
Mir96rno-miR-96-5pMirtarbaseexternal_infoWestern blotFunctional MTI19167416

Predicted Target Of
Summary Value
Count of predictions:204
Count of miRNA genes:140
Interacting mature miRNAs:164
Transcripts:ENSRNOT00000051121
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 42 23 6 2
Low 3 1 57 41 19 41 8 11 74 12 32 9 8
Below cutoff 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000051121   ⟹   ENSRNOP00000044350
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4130,172,727 - 130,422,735 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083127   ⟹   ENSRNOP00000073565
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4130,332,076 - 130,425,532 (+)Ensembl
RefSeq Acc Id: NM_001191089   ⟹   NP_001178018
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,217 - 130,621,145 (+)NCBI
Rnor_6.04130,172,856 - 130,425,496 (+)NCBI
Rnor_5.04194,667,943 - 194,921,498 (+)NCBI
Celera4119,282,401 - 119,497,938 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592477   ⟹   XP_017447966
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,024 - 130,621,145 (+)NCBI
Rnor_6.04130,172,484 - 130,425,496 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592478   ⟹   XP_017447967
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,526,535 - 130,617,941 (+)NCBI
Rnor_6.04130,332,222 - 130,425,496 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107083   ⟹   XP_038963011
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,020 - 130,617,941 (+)NCBI
RefSeq Acc Id: XM_039107085   ⟹   XP_038963013
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,217 - 130,617,941 (+)NCBI
RefSeq Acc Id: XM_039107086   ⟹   XP_038963014
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,526,535 - 130,617,941 (+)NCBI
RefSeq Acc Id: XM_039107087   ⟹   XP_038963015
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,427,689 - 130,617,941 (+)NCBI
RefSeq Acc Id: XM_039107088   ⟹   XP_038963016
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,284 - 130,617,941 (+)NCBI
RefSeq Acc Id: XM_039107089   ⟹   XP_038963017
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24130,409,024 - 130,621,145 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001178018   ⟸   NM_001191089
- UniProtKB: O88368 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017447966   ⟸   XM_017592477
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017447967   ⟸   XM_017592478
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K5U8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000044350   ⟸   ENSRNOT00000051121
RefSeq Acc Id: ENSRNOP00000073565   ⟸   ENSRNOT00000083127
RefSeq Acc Id: XP_038963011   ⟸   XM_039107083
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038963017   ⟸   XM_039107089
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038963013   ⟸   XM_039107085
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963016   ⟸   XM_039107088
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038963015   ⟸   XM_039107087
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038963014   ⟸   XM_039107086
- Peptide Label: isoform X5
Protein Domains
bHLH

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693271
Promoter ID:EPDNEW_R3796
Type:single initiation site
Name:Mitf_1
Description:melanogenesis associated transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04130,172,727 - 130,172,787EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3092 AgrOrtholog
Ensembl Genes ENSRNOG00000008658 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000044350 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000073565 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000051121 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000083127 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MiT/TFE_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MiT/TFE_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MITF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25094 UniProtKB/Swiss-Prot
NCBI Gene 25094 ENTREZGENE
PANTHER PTHR45776:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF3371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MITF_TFEB_C_3_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mitf PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K5U8 ENTREZGENE, UniProtKB/TrEMBL
  MITF_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary F1LQV3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-10-16 Mitf  melanocyte inducing transcription factor  Mitf  melanogenesis associated transcription factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-06-02 Mitf  melanogenesis associated transcription factor  Mitf  microphthalmia-associated transcription factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Mitf  Microphthalmia-associated transcription factor      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease deletion in gene may be associated with osteopetrosis 729082
gene_process may be involved in pigmentation, mast cells, and bone development 729082