Gene: Prps1 (phosphoribosyl pyrophosphate synthetase 1) Rattus norvegicus
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Symbol: Prps1
Name: phosphoribosyl pyrophosphate synthetase 1
Description: Exhibits several functions, including anion binding activity, carbohydrate binding activity, and cation binding activity; involved in 5-phosphoribose 1-diphosphate biosynthetic process, AMP biosynthetic process, and animal organ regeneration; localizes to the ribose phosphate diphosphokinase complex; orthologous to human PRPS1 (phosphoribosyl pyrophosphate synthetase 1); PARTICIPATES IN de novo purine biosynthetic pathway; pentose phosphate pathway; purine metabolic pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: phosphoribosyl pyrophosphate synthase I; phosphoribosyl pyrophosphate synthetase I; PRS-I; ribose-phosphate pyrophosphokinase 1
Orthologs:
Homo sapiens (human) : PRPS1 (phosphoribosyl pyrophosphate synthetase 1)  HGNC  Alliance
Mus musculus (house mouse) : Prps1 (phosphoribosyl pyrophosphate synthetase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prps1 (phosphoribosyl pyrophosphate synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PRPS1 (phosphoribosyl pyrophosphate synthetase 1)
Canis lupus familiaris (dog) : PRPS1 (phosphoribosyl pyrophosphate synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prps1 (phosphoribosyl pyrophosphate synthetase 1)
Sus scrofa (pig) : PRPS1 (phosphoribosyl pyrophosphate synthetase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X111,798,233 - 111,820,270 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0352,779,462 - 52,801,499 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X128,249,843 - 128,271,893 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X128,323,278 - 128,345,324 (+)NCBI
Celera343,777,612 - 43,799,661 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prps1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61955
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.