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Gene: Eif4e (eukaryotic translation initiation factor 4E) Rattus norvegicus
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Symbol: Eif4e
Name: eukaryotic translation initiation factor 4E
Description: Exhibits eukaryotic initiation factor 4G binding activity. Involved in lung development. Localizes to the eukaryotic translation initiation factor 4F complex; glutamatergic synapse; and postsynaptic cytosol. Biomarker of vascular dementia. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human EIF4E (eukaryotic translation initiation factor 4E); PARTICIPATES IN CRM1 export pathway; mTOR signaling pathway; translation initiation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: eIF-4E; eIF-4F 25 kDa subunit; eukaryotic initiation factor 4E; MGC93265; mRNA cap-binding protein
Orthologs:
Homo sapiens (human) : EIF4E (eukaryotic translation initiation factor 4E)  HGNC  Alliance
Mus musculus (house mouse) : Eif4e (eukaryotic translation initiation factor 4E)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eif4e (eukaryotic translation initiation factor 4E)
Pan paniscus (bonobo/pygmy chimpanzee) : EIF4E (eukaryotic translation initiation factor 4E)
Canis lupus familiaris (dog) : EIF4E (eukaryotic translation initiation factor 4E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eif4e (eukaryotic translation initiation factor 4E)
Sus scrofa (pig) : EIF4E (eukaryotic translation initiation factor 4E)
Chlorocebus sabaeus (African green monkey) : EIF4E (eukaryotic translation initiation factor 4E)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02243,819,616 - 243,853,987 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,820,661 - 243,852,631 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02262,354,375 - 262,387,512 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42236,072,748 - 236,104,714 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12236,059,487 - 236,091,453 (+)NCBI
Celera2219,223,372 - 219,255,078 (+)NCBICelera
Cytogenetic Map2q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Eif4e
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69647
Created: 2001-12-06
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.