Eif4e Rat (-)-anisomycin increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Anisomycin results in increased phosphorylation of EIF4E protein CTD PMID:9545260 Eif4e Rat (-)-anisomycin increases phosphorylation ISO Eif4e (Mus musculus) 6480464 Anisomycin results in increased phosphorylation of EIF4E protein CTD PMID:9545260 Eif4e Rat (-)-anisomycin multiple interactions ISO Eif4e (Mus musculus) 6480464 SB 203580 inhibits the reaction [Anisomycin results in increased phosphorylation of EIF4E protein] CTD PMID:9545260 Eif4e Rat (-)-anisomycin multiple interactions ISO EIF4E (Homo sapiens) 6480464 SB 203580 inhibits the reaction [Anisomycin results in increased phosphorylation of EIF4E protein] CTD PMID:9545260 Eif4e Rat (S)-nicotine multiple interactions ISO Eif4e (Mus musculus) 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Eif4e Rat (S)-nicotine multiple interactions ISO EIF4E (Homo sapiens) 6480464 EIF4E protein affects the reaction [Nicotine results in increased expression of BCL2 protein] more ... CTD PMID:30836163 Eif4e Rat 1,2-dichloroethane increases expression ISO Eif4e (Mus musculus) 6480464 ethylene dichloride results in increased expression of EIF4E mRNA CTD PMID:28960355 Eif4e Rat 1,2-dimethylhydrazine decreases expression ISO Eif4e (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of EIF4E mRNA CTD PMID:22206623 Eif4e Rat 1,2-dimethylhydrazine multiple interactions ISO Eif4e (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4E mRNA CTD PMID:22206623 Eif4e Rat 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Eif4e (Mus musculus) 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Eif4e Rat 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Eif4e (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Eif4e Rat 17alpha-ethynylestradiol affects expression ISO Eif4e (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of EIF4E mRNA CTD PMID:17555576 Eif4e Rat 17alpha-ethynylestradiol increases expression ISO Eif4e (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of EIF4E mRNA CTD PMID:16174780 and PMID:17942748 Eif4e Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of EIF4E mRNA CTD PMID:16174780 Eif4e Rat 17alpha-ethynylestradiol multiple interactions ISO Eif4e (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EIF4E mRNA CTD PMID:17942748 Eif4e Rat 17beta-estradiol decreases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Estradiol results in decreased phosphorylation of EIF4E protein CTD PMID:16033851 Eif4e Rat 17beta-estradiol increases expression ISO EIF4E (Homo sapiens) 6480464 Estradiol results in increased expression of EIF4E mRNA CTD PMID:31614463 Eif4e Rat 17beta-estradiol affects expression ISO EIF4E (Homo sapiens) 6480464 Estradiol affects the expression of EIF4E mRNA CTD PMID:21826169 Eif4e Rat 17beta-estradiol multiple interactions ISO EIF4E (Homo sapiens) 6480464 everolimus inhibits the reaction [Estradiol results in decreased phosphorylation of EIF4E protein] CTD PMID:16033851 Eif4e Rat 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Eif4e (Mus musculus) 6480464 2 more ... CTD PMID:30294300 Eif4e Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO EIF4E (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of EIF4E mRNA CTD PMID:15056799 Eif4e Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Eif4e (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of EIF4E mRNA CTD PMID:21570461 Eif4e Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Eif4e (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of EIF4E mRNA CTD PMID:17942748 Eif4e Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Eif4e (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EIF4E mRNA CTD PMID:17942748 Eif4e Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of EIF4E mRNA CTD PMID:21346803 Eif4e Rat 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of EIF4E mRNA CTD PMID:21346803 Eif4e Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO EIF4E (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of EIF4E mRNA CTD PMID:28628672 Eif4e Rat 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of EIF4E mRNA CTD PMID:19162173 Eif4e Rat 4,4'-diaminodiphenylmethane decreases expression ISO Eif4e (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of EIF4E mRNA CTD PMID:18648102 Eif4e Rat 4,4'-sulfonyldiphenol decreases methylation ISO EIF4E (Homo sapiens) 6480464 bisphenol S results in decreased methylation of EIF4E gene CTD PMID:31601247 Eif4e Rat 4-hydroxynon-2-enal increases expression ISO Eif4e (Mus musculus) 6480464 4-hydroxy-2-nonenal results in increased expression of EIF4E mRNA CTD PMID:19191707 Eif4e Rat 5-chloro-7-iodoquinolin-8-ol multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E mRNA and [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E protein CTD PMID:22415087 Eif4e Rat 5-fluorouracil multiple interactions ISO EIF4E (Homo sapiens) 6480464 Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] and TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIF4E mRNA] CTD PMID:15016801 and PMID:15611226 Eif4e Rat 5-fluorouracil increases expression ISO EIF4E (Homo sapiens) 6480464 Fluorouracil results in increased expression of EIF4E mRNA CTD PMID:16584549 Eif4e Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of EIF4E mRNA CTD PMID:30047161 Eif4e Rat 7-methyl-7,8-dihydroguanosine-5'-diphosphate affects binding ISO EIF4E (Homo sapiens) 6480464 7-methylguanosine 5'-diphosphate analog binds to EIF4E protein CTD PMID:27592390 Eif4e Rat 7-methyl-7,8-dihydroguanosine-5'-diphosphate multiple interactions ISO EIF4E (Homo sapiens) 6480464 7-methylguanosine triphosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein] more ... CTD PMID:27592390 Eif4e Rat 7-methyl-GTP multiple interactions ISO EIF4E (Homo sapiens) 6480464 7-methylguanosine triphosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein] and 7-methylguanosine triphosphate inhibits the reaction [RNA Caps binds to EIF4E protein] CTD PMID:27592390 Eif4e Rat acetylleucyl-leucyl-norleucinal multiple interactions ISO EIF4E (Homo sapiens) 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium Chloride results in decreased expression of EIF4E protein] CTD PMID:15878868 Eif4e Rat acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of EIF4E mRNA CTD PMID:28959563 Eif4e Rat actinomycin D multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of EIF4E protein CTD PMID:38460933 Eif4e Rat aldehydo-D-glucose increases phosphorylation ISO Eif4e (Mus musculus) 6480464 Glucose results in increased phosphorylation of EIF4E protein CTD PMID:19765649 Eif4e Rat aldehydo-D-glucose multiple interactions ISO Eif4e (Mus musculus) 6480464 Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein] more ... CTD PMID:19765649 Eif4e Rat all-trans-retinoic acid multiple interactions ISO EIF4E (Homo sapiens) 6480464 Thiophenes analog promotes the reaction [Tretinoin results in decreased expression of EIF4E mRNA] CTD PMID:16140955 Eif4e Rat all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of EIF4E mRNA CTD PMID:24977338 Eif4e Rat all-trans-retinoic acid decreases expression ISO EIF4E (Homo sapiens) 6480464 Tretinoin results in decreased expression of EIF4E mRNA CTD PMID:16140955 and PMID:33167477 Eif4e Rat amiodarone multiple interactions ISO EIF4E (Homo sapiens) 6480464 Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 Eif4e Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of EIF4E mRNA CTD PMID:30047161 Eif4e Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of EIF4E mRNA CTD PMID:16483693 Eif4e Rat arsenite(3-) increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 arsenite results in increased phosphorylation of EIF4E protein CTD PMID:12781867 and PMID:9545260 Eif4e Rat arsenite(3-) multiple interactions ISO EIF4E (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenite results in increased phosphorylation of EIF4E protein] more ... CTD PMID:12781867 and PMID:9545260 Eif4e Rat arsenous acid affects expression ISO EIF4E (Homo sapiens) 6480464 Arsenic Trioxide affects the expression of EIF4E mRNA CTD PMID:20458559 Eif4e Rat arsenous acid multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein] which results in increased phosphorylation of EIF4E protein more ... CTD PMID:18299328 and PMID:29042487 Eif4e Rat arsenous acid increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of EIF4E protein CTD PMID:29042487 Eif4e Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of EIF4E gene CTD PMID:28931070 and PMID:35440735 Eif4e Rat benzo[a]pyrene increases expression ISO Eif4e (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of EIF4E mRNA CTD PMID:20127859 and PMID:22228805 Eif4e Rat benzo[a]pyrene decreases methylation ISO Eif4e (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of EIF4E exon and Benzo(a)pyrene results in decreased methylation of EIF4E intron CTD PMID:27901495 Eif4e Rat benzo[a]pyrene diol epoxide I decreases expression ISO EIF4E (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 Eif4e Rat bisphenol A increases expression ISO EIF4E (Homo sapiens) 6480464 bisphenol A results in increased expression of EIF4E mRNA CTD PMID:21890461 Eif4e Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EIF4E mRNA and bisphenol A results in increased expression of EIF4E protein CTD PMID:25181051 more ... Eif4e Rat bisphenol A affects expression ISO EIF4E (Homo sapiens) 6480464 bisphenol A affects the expression of EIF4E mRNA CTD PMID:21826169 Eif4e Rat bisphenol F multiple interactions ISO EIF4E (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of EIF4E mRNA CTD PMID:28628672 Eif4e Rat cadmium dichloride multiple interactions ISO EIF4E (Homo sapiens) 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium Chloride results in decreased expression of EIF4E protein] more ... CTD PMID:15878868 Eif4e Rat cadmium dichloride increases expression ISO EIF4E (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of EIF4E protein CTD PMID:24527689 and PMID:26220685 Eif4e Rat cadmium dichloride decreases response to substance ISO EIF4E (Homo sapiens) 6480464 EIF4E results in decreased susceptibility to Cadmium Chloride CTD PMID:15878868 Eif4e Rat cadmium dichloride decreases expression ISO EIF4E (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of EIF4E protein CTD PMID:15878868 Eif4e Rat caffeine multiple interactions ISO Eif4e (Mus musculus) 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Eif4e Rat caffeine increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Caffeine results in increased phosphorylation of EIF4E protein CTD PMID:35688186 Eif4e Rat cannabidiol multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Cannabidiol co-treated with moringin] results in increased expression of EIF4E mRNA CTD PMID:30096889 Eif4e Rat carbon nanotube increases expression ISO Eif4e (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 Eif4e Rat carbon nanotube decreases methylation ISO EIF4E (Homo sapiens) 6480464 Nanotubes and Carbon results in decreased methylation of EIF4E gene CTD PMID:29426343 Eif4e Rat cisplatin multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of EIF4E mRNA more ... CTD PMID:21858171 more ... Eif4e Rat cisplatin decreases expression ISO EIF4E (Homo sapiens) 6480464 Cisplatin results in decreased expression of EIF4E mRNA CTD PMID:27594783 Eif4e Rat cisplatin increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Cisplatin results in increased phosphorylation of EIF4E protein CTD PMID:25923732 Eif4e Rat clozapine multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Cuprizone co-treated with Clozapine] results in increased expression of EIF4E protein CTD PMID:34122009 Eif4e Rat copper atom multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in decreased expression of EIF4E mRNA CTD PMID:30911355 Eif4e Rat copper(0) multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in decreased expression of EIF4E mRNA CTD PMID:30911355 Eif4e Rat copper(II) sulfate decreases expression ISO EIF4E (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of EIF4E mRNA CTD PMID:19549813 Eif4e Rat Cuprizon multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Cuprizone co-treated with Clozapine] results in increased expression of EIF4E protein CTD PMID:34122009 Eif4e Rat cycloheximide multiple interactions ISO EIF4E (Homo sapiens) 6480464 Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of CCND1 protein]] more ... CTD PMID:25923732 Eif4e Rat cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein] CTD PMID:22689575 Eif4e Rat cypermethrin increases expression ISO Eif4e (Mus musculus) 6480464 cypermethrin results in increased expression of EIF4E mRNA CTD PMID:29020013 Eif4e Rat D-glucitol multiple interactions ISO EIF4E (Homo sapiens) 6480464 Sorbitol promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:9545260 Eif4e Rat D-glucose multiple interactions ISO Eif4e (Mus musculus) 6480464 Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein] more ... CTD PMID:19765649 Eif4e Rat D-glucose increases phosphorylation ISO Eif4e (Mus musculus) 6480464 Glucose results in increased phosphorylation of EIF4E protein CTD PMID:19765649 Eif4e Rat DDE increases expression ISO EIF4E (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of EIF4E mRNA CTD PMID:38568856 Eif4e Rat dexamethasone multiple interactions ISO EIF4E (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of EIF4E mRNA CTD PMID:28628672 Eif4e Rat diarsenic trioxide affects expression ISO EIF4E (Homo sapiens) 6480464 Arsenic Trioxide affects the expression of EIF4E mRNA CTD PMID:20458559 Eif4e Rat diarsenic trioxide multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein] which results in increased phosphorylation of EIF4E protein more ... CTD PMID:18299328 and PMID:29042487 Eif4e Rat diarsenic trioxide increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of EIF4E protein CTD PMID:29042487 Eif4e Rat Dibutyl phosphate affects expression ISO EIF4E (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of EIF4E mRNA CTD PMID:37042841 Eif4e Rat dibutyl phthalate decreases expression ISO Eif4e (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of EIF4E mRNA CTD PMID:21266533 Eif4e Rat dibutylstannane affects phosphorylation ISO EIF4E (Homo sapiens) 6480464 di-n-butyltin affects the phosphorylation of EIF4E protein CTD PMID:36372856 Eif4e Rat dicrotophos decreases expression ISO EIF4E (Homo sapiens) 6480464 dicrotophos results in decreased expression of EIF4E mRNA CTD PMID:28302478 Eif4e Rat Dictamnine multiple interactions ISO EIF4E (Homo sapiens) 6480464 [dictamnine co-treated with Oxygen deficiency] results in decreased phosphorylation of EIF4E protein CTD PMID:30266538 Eif4e Rat Dihydrotanshinone I decreases phosphorylation ISO EIF4E (Homo sapiens) 6480464 dihydrotanshinone I results in decreased phosphorylation of EIF4E protein CTD PMID:26282490 Eif4e Rat dioxygen multiple interactions ISO EIF4E (Homo sapiens) 6480464 [dictamnine co-treated with Oxygen deficiency] results in decreased phosphorylation of EIF4E protein CTD PMID:30266538 Eif4e Rat doxorubicin decreases expression ISO EIF4E (Homo sapiens) 6480464 Doxorubicin results in decreased expression of EIF4E mRNA CTD PMID:29803840 Eif4e Rat doxorubicin increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Doxorubicin results in increased phosphorylation of EIF4E protein CTD PMID:29112301 Eif4e Rat doxorubicin multiple interactions ISO EIF4E (Homo sapiens) 6480464 Ribavirin inhibits the reaction [Doxorubicin results in increased phosphorylation of EIF4E protein] CTD PMID:29112301 Eif4e Rat ethyl methanesulfonate decreases expression ISO EIF4E (Homo sapiens) 6480464 Ethyl Methanesulfonate results in decreased expression of EIF4E mRNA CTD PMID:23649840 Eif4e Rat everolimus multiple interactions ISO EIF4E (Homo sapiens) 6480464 Everolimus inhibits the reaction [Estradiol results in decreased phosphorylation of EIF4E protein] CTD PMID:16033851 Eif4e Rat everolimus increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Everolimus results in increased phosphorylation of EIF4E protein CTD PMID:16033851 Eif4e Rat flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of EIF4E mRNA CTD PMID:18035473 Eif4e Rat fluoxetine increases phosphorylation EXP 6480464 Fluoxetine results in increased phosphorylation of EIF4E protein CTD PMID:16817885 Eif4e Rat flurbiprofen increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Flurbiprofen results in increased phosphorylation of EIF4E protein CTD PMID:18056468 Eif4e Rat flurbiprofen multiple interactions ISO EIF4E (Homo sapiens) 6480464 MAPK14 protein promotes the reaction [Flurbiprofen results in increased phosphorylation of EIF4E protein] CTD PMID:18056468 Eif4e Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of EIF4E mRNA CTD PMID:24136188 Eif4e Rat folic acid multiple interactions ISO Eif4e (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF4E mRNA CTD PMID:22206623 Eif4e Rat formaldehyde decreases expression ISO EIF4E (Homo sapiens) 6480464 Formaldehyde results in decreased expression of EIF4E mRNA CTD PMID:23649840 Eif4e Rat genistein decreases expression ISO EIF4E (Homo sapiens) 6480464 Genistein results in decreased expression of EIF4E mRNA CTD PMID:22228119 Eif4e Rat glucose multiple interactions ISO Eif4e (Mus musculus) 6480464 Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein] more ... CTD PMID:19765649 Eif4e Rat glucose increases phosphorylation ISO Eif4e (Mus musculus) 6480464 Glucose results in increased phosphorylation of EIF4E protein CTD PMID:19765649 Eif4e Rat gold atom multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in decreased expression of EIF4E protein CTD PMID:27470402 Eif4e Rat gold(0) multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in decreased expression of EIF4E protein CTD PMID:27470402 Eif4e Rat guanosine affects binding ISO EIF4E (Homo sapiens) 6480464 Guanosine analog binds to EIF4E protein CTD PMID:27592390 Eif4e Rat guanosine multiple interactions ISO EIF4E (Homo sapiens) 6480464 Guanosine analog inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein] and Guanosine analog inhibits the reaction [RNA Caps binds to EIF4E protein] CTD PMID:27592390 Eif4e Rat hyaluronic acid increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Hyaluronic Acid results in increased phosphorylation of EIF4E protein CTD PMID:16864594 Eif4e Rat hydrogen peroxide multiple interactions ISO EIF4E (Homo sapiens) 6480464 Hydrogen Peroxide promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:9545260 Eif4e Rat ibuprofen multiple interactions ISO EIF4E (Homo sapiens) 6480464 MAPK14 protein promotes the reaction [Ibuprofen results in increased phosphorylation of EIF4E protein] CTD PMID:18056468 Eif4e Rat ibuprofen increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Ibuprofen results in increased phosphorylation of EIF4E protein CTD PMID:18056468 Eif4e Rat indometacin multiple interactions ISO EIF4E (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of EIF4E mRNA CTD PMID:28628672 Eif4e Rat irinotecan multiple interactions ISO Eif4e (Mus musculus) 6480464 [PHY 906 co-treated with Irinotecan] affects the expression of EIF4E mRNA CTD PMID:32812032 Eif4e Rat isoprenaline decreases expression ISO Eif4e (Mus musculus) 6480464 Isoproterenol results in decreased expression of EIF4E mRNA CTD PMID:20003209 Eif4e Rat isotretinoin decreases expression ISO EIF4E (Homo sapiens) 6480464 Isotretinoin results in decreased expression of EIF4E mRNA CTD PMID:20436886 Eif4e Rat ivermectin decreases expression ISO EIF4E (Homo sapiens) 6480464 Ivermectin results in decreased expression of EIF4E protein CTD PMID:32959892 Eif4e Rat jaspamide multiple interactions ISO EIF4E (Homo sapiens) 6480464 jasplakinolide inhibits the reaction [EIF4E protein affects the expression of CDH1 protein] more ... CTD PMID:20388789 Eif4e Rat kojic acid decreases expression ISO EIF4E (Homo sapiens) 6480464 kojic acid results in decreased expression of EIF4E mRNA CTD PMID:16595896 Eif4e Rat lactacystin multiple interactions ISO EIF4E (Homo sapiens) 6480464 lactacystin inhibits the reaction [Cadmium Chloride results in decreased expression of EIF4E protein] CTD PMID:15878868 Eif4e Rat linuron decreases expression EXP 6480464 Linuron results in decreased expression of EIF4E mRNA CTD PMID:28705778 Eif4e Rat lipopolysaccharide multiple interactions ISO Eif4e (Mus musculus) 6480464 [SB 203580 co-treated with U 0126] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EIF4E protein] more ... CTD PMID:16431125 more ... Eif4e Rat lipopolysaccharide increases phosphorylation ISO Eif4e (Mus musculus) 6480464 Lipopolysaccharides results in increased phosphorylation of EIF4E protein CTD PMID:16431125 Eif4e Rat lipopolysaccharide increases activity ISO Eif4e (Mus musculus) 6480464 Lipopolysaccharides results in increased activity of EIF4E protein CTD PMID:21291324 Eif4e Rat LY294002 multiple interactions ISO EIF4E (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [arsenite results in increased phosphorylation of EIF4E protein] CTD PMID:12781867 Eif4e Rat LY294002 decreases phosphorylation ISO EIF4E (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of EIF4E protein CTD PMID:26282490 Eif4e Rat metformin decreases expression ISO EIF4E (Homo sapiens) 6480464 Metformin results in decreased expression of EIF4E mRNA CTD PMID:32589349 Eif4e Rat metformin multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Metformin co-treated with Pioglitazone] results in decreased expression of EIF4E mRNA CTD PMID:32589349 Eif4e Rat methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of EIF4E mRNA CTD PMID:30467583 Eif4e Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of EIF4E mRNA CTD PMID:30047161 Eif4e Rat methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of EIF4E gene CTD PMID:23303685 Eif4e Rat methyl methanesulfonate decreases expression ISO EIF4E (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of EIF4E mRNA CTD PMID:23649840 Eif4e Rat N-Acetyl-S-(1,2-dichlorovinyl)-cysteine affects expression ISO EIF4E (Homo sapiens) 6480464 S-1 and 2-dichlorovinyl-N-acetylcysteine affects the expression of EIF4E mRNA CTD PMID:16844155 Eif4e Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO EIF4E (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in decreased expression of EIF4E protein] CTD PMID:15878868 Eif4e Rat naphthalene multiple interactions ISO Eif4e (Mus musculus) 6480464 [naphthalene co-treated with AKT1] results in increased expression of EIF4E protein and [naphthalene co-treated with AKT1] results in increased phosphorylation of EIF4E protein CTD PMID:22122896 Eif4e Rat nefazodone increases expression EXP 6480464 nefazodone results in increased expression of EIF4E mRNA CTD PMID:24136188 Eif4e Rat niclosamide multiple interactions ISO EIF4E (Homo sapiens) 6480464 Niclosamide promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 Eif4e Rat nicotine multiple interactions ISO Eif4e (Mus musculus) 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Eif4e Rat nicotine multiple interactions ISO EIF4E (Homo sapiens) 6480464 EIF4E protein affects the reaction [Nicotine results in increased expression of BCL2 protein] more ... CTD PMID:30836163 Eif4e Rat Nutlin-3 multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of EIF4E protein CTD PMID:38460933 Eif4e Rat orlistat increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 orlistat results in increased phosphorylation of EIF4E protein CTD PMID:18796435 Eif4e Rat oxybenzone increases expression ISO EIF4E (Homo sapiens) 6480464 oxybenzone results in increased expression of EIF4E mRNA CTD PMID:36581016 Eif4e Rat ozone multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of EIF4E mRNA CTD PMID:35430440 Eif4e Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of EIF4E mRNA CTD PMID:19162173 Eif4e Rat perhexiline multiple interactions ISO EIF4E (Homo sapiens) 6480464 Perhexiline promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 Eif4e Rat phenanthrene increases expression ISO Eif4e (Mus musculus) 6480464 phenanthrene results in increased expression of EIF4E mRNA CTD PMID:34453960 Eif4e Rat phenobarbital increases expression ISO Eif4e (Mus musculus) 6480464 Phenobarbital results in increased expression of EIF4E mRNA CTD PMID:19363144 Eif4e Rat phenylephrine multiple interactions EXP 6480464 CGP 57380 inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4E protein] more ... CTD PMID:15757502 Eif4e Rat phenylephrine increases phosphorylation EXP 6480464 Phenylephrine results in increased phosphorylation of EIF4E protein CTD PMID:15757502 Eif4e Rat phorbol 13-acetate 12-myristate multiple interactions ISO EIF4E (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein] more ... CTD PMID:12781867 and PMID:9545260 Eif4e Rat phorbol 13-acetate 12-myristate increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein CTD PMID:12781867 and PMID:9545260 Eif4e Rat pioglitazone multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Metformin co-treated with Pioglitazone] results in decreased expression of EIF4E mRNA CTD PMID:32589349 Eif4e Rat piroxicam multiple interactions ISO EIF4E (Homo sapiens) 6480464 Cisplatin affects the reaction [Piroxicam results in decreased expression of EIF4E mRNA] CTD PMID:21858171 Eif4e Rat piroxicam decreases expression ISO EIF4E (Homo sapiens) 6480464 Piroxicam results in decreased expression of EIF4E mRNA CTD PMID:21858171 Eif4e Rat pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of EIF4E mRNA CTD PMID:30047161 Eif4e Rat propiconazole increases expression ISO Eif4e (Mus musculus) 6480464 propiconazole results in increased expression of EIF4E mRNA CTD PMID:19363144 and PMID:21278054 Eif4e Rat quercetin multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in decreased expression of EIF4E protein and Quercetin inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] CTD PMID:15611226 and PMID:27470402 Eif4e Rat quinolone multiple interactions ISO EIF4E (Homo sapiens) 6480464 Quinolones inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein] and Quinolones inhibits the reaction [RNA Caps binds to EIF4E protein] CTD PMID:27592390 Eif4e Rat resveratrol multiple interactions ISO EIF4E (Homo sapiens) 6480464 resveratrol inhibits the reaction [IGF1 protein results in increased phosphorylation of EIF4E protein] CTD PMID:15297429 Eif4e Rat resveratrol multiple interactions ISO Eif4e (Mus musculus) 6480464 resveratrol inhibits the reaction [Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]] and resveratrol inhibits the reaction [Glucose results in increased phosphorylation of EIF4E protein] CTD PMID:19765649 Eif4e Rat ribavirin decreases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Ribavirin results in decreased phosphorylation of EIF4E protein CTD PMID:29112301 Eif4e Rat ribavirin decreases expression ISO EIF4E (Homo sapiens) 6480464 Ribavirin results in decreased expression of EIF4E mRNA and Ribavirin results in decreased expression of EIF4E protein CTD PMID:33577917 and PMID:34919946 Eif4e Rat ribavirin multiple interactions ISO EIF4E (Homo sapiens) 6480464 Ribavirin inhibits the reaction [CARM1 protein binds to EIF4E promoter] and Ribavirin inhibits the reaction [Doxorubicin results in increased phosphorylation of EIF4E protein] CTD PMID:29112301 and PMID:34919946 Eif4e Rat rottlerin multiple interactions ISO EIF4E (Homo sapiens) 6480464 rottlerin promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 Eif4e Rat SB 203580 multiple interactions ISO EIF4E (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]] more ... CTD PMID:12781867 and PMID:9545260 Eif4e Rat SB 203580 multiple interactions ISO Eif4e (Mus musculus) 6480464 [SB 203580 co-treated with U 0126] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EIF4E protein] and SB 203580 inhibits the reaction [Anisomycin results in increased phosphorylation of EIF4E protein] CTD PMID:16431125 and PMID:9545260 Eif4e Rat sirolimus multiple interactions ISO EIF4E (Homo sapiens) 6480464 EIF4E protein inhibits the reaction [Sirolimus results in decreased expression of MDM2 protein] CTD PMID:19560264 Eif4e Rat sirolimus increases expression ISO Eif4e (Mus musculus) 6480464 Sirolimus results in increased expression of EIF4E mRNA CTD PMID:34453960 Eif4e Rat sirolimus increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 Sirolimus results in increased phosphorylation of EIF4E protein CTD PMID:26282490 Eif4e Rat sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4E protein] CTD PMID:15757502 Eif4e Rat sirolimus decreases activity ISO EIF4E (Homo sapiens) 6480464 Sirolimus results in decreased activity of EIF4E protein CTD PMID:19560264 Eif4e Rat sodium arsenite multiple interactions ISO EIF4E (Homo sapiens) 6480464 CGP 57380 inhibits the reaction [sodium arsenite promotes the reaction [EIF4E protein modified form binds to EIF4ENIF1 protein]] more ... CTD PMID:16283521 more ... Eif4e Rat sodium arsenite decreases expression ISO EIF4E (Homo sapiens) 6480464 sodium arsenite results in decreased expression of EIF4E mRNA CTD PMID:38568856 Eif4e Rat sodium arsenite affects methylation ISO EIF4E (Homo sapiens) 6480464 sodium arsenite affects the methylation of EIF4E gene CTD PMID:28589171 Eif4e Rat sodium arsenite increases phosphorylation ISO EIF4E (Homo sapiens) 6480464 sodium arsenite results in increased phosphorylation of EIF4E protein CTD PMID:25923732 Eif4e Rat sodium arsenite increases expression ISO EIF4E (Homo sapiens) 6480464 sodium arsenite results in increased expression of EIF4E mRNA CTD PMID:12016162 more ... Eif4e Rat sodium arsenite affects localization ISO EIF4E (Homo sapiens) 6480464 sodium arsenite affects the localization of EIF4E protein CTD PMID:16951406 Eif4e Rat sodium arsenite decreases response to substance ISO EIF4E (Homo sapiens) 6480464 EIF4E protein modified form results in decreased susceptibility to sodium arsenite and EIF4E protein results in decreased susceptibility to sodium arsenite CTD PMID:16283521 and PMID:25923732 Eif4e Rat sodium arsenite increases response to substance ISO EIF4E (Homo sapiens) 6480464 EIF4E mutant form results in increased susceptibility to sodium arsenite CTD PMID:25923732 Eif4e Rat sorafenib multiple interactions ISO EIF4E (Homo sapiens) 6480464 [sorafenib results in decreased phosphorylation of EIF4E protein] which results in decreased expression of MCL1 and sorafenib inhibits the reaction [MKNK1 protein results in increased phosphorylation of EIF4E protein] CTD PMID:16109713 and PMID:21750559 Eif4e Rat sorafenib decreases phosphorylation ISO EIF4E (Homo sapiens) 6480464 sorafenib results in decreased phosphorylation of EIF4E protein CTD PMID:16109713 and PMID:21750559 Eif4e Rat sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of EIF4E mRNA CTD PMID:30047161 Eif4e Rat tamoxifen affects expression ISO Eif4e (Mus musculus) 6480464 Tamoxifen affects the expression of EIF4E mRNA CTD PMID:17555576 Eif4e Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of EIF4E mRNA CTD PMID:31150632 Eif4e Rat tetrachloromethane increases expression ISO Eif4e (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of EIF4E mRNA CTD PMID:31919559 Eif4e Rat thalidomide decreases expression EXP 6480464 Thalidomide results in decreased expression of EIF4E protein CTD PMID:18291259 Eif4e Rat thapsigargin decreases expression ISO Eif4e (Mus musculus) 6480464 Thapsigargin results in decreased expression of EIF4E mRNA and Thapsigargin results in decreased expression of EIF4E protein CTD PMID:24648495 Eif4e Rat thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of EIF4E protein CTD PMID:35544339 Eif4e Rat thiophenes multiple interactions ISO EIF4E (Homo sapiens) 6480464 Thiophenes analog promotes the reaction [Tretinoin results in decreased expression of EIF4E mRNA] CTD PMID:16140955 Eif4e Rat triadimefon increases expression ISO Eif4e (Mus musculus) 6480464 triadimefon results in increased expression of EIF4E mRNA CTD PMID:19363144 Eif4e Rat tributylstannane multiple interactions ISO EIF4E (Homo sapiens) 6480464 tributyltin affects the expression of and results in increased phosphorylation of EIF4E protein CTD PMID:36372856 Eif4e Rat trichostatin A affects expression ISO EIF4E (Homo sapiens) 6480464 trichostatin A affects the expression of EIF4E mRNA CTD PMID:28542535 Eif4e Rat triphenyl phosphate affects expression ISO EIF4E (Homo sapiens) 6480464 triphenyl phosphate affects the expression of EIF4E mRNA CTD PMID:37042841 Eif4e Rat Triptolide increases expression ISO Eif4e (Mus musculus) 6480464 triptolide results in increased expression of EIF4E mRNA CTD PMID:32835833 Eif4e Rat triptonide increases expression ISO Eif4e (Mus musculus) 6480464 triptonide results in increased expression of EIF4E mRNA CTD PMID:33045310 Eif4e Rat tunicamycin increases expression ISO Eif4e (Mus musculus) 6480464 Tunicamycin results in increased expression of EIF4E mRNA CTD PMID:17127020 Eif4e Rat valproic acid decreases expression ISO Eif4e (Mus musculus) 6480464 Valproic Acid results in decreased expression of EIF4E mRNA CTD PMID:20546886 Eif4e Rat zinc dichloride multiple interactions ISO EIF4E (Homo sapiens) 6480464 [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E mRNA and [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E protein CTD PMID:22415087