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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69647
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eif4e
Name: eukaryotic translation initiation factor 4E
Acc ID: CHEBI:43977
Term: 7-methyl-7,8-dihydroguanosine-5'-diphosphate
Definition: A purine ribonucleoside 5'-diphosphate having 7-methyl-7,8-dihydroguanine as the nucleobase.
Chemical ID: MESH:C111106
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif4eaffects bindingISORGD:7328336480464CTD7-methylguanosine 5'-diphosphate analog binds to EIF4E protein

PMID:27592390
Eif4emultiple interactionsISORGD:7328336480464CTD7-methylguanosine triphosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein] 7-methylguanosine-5'-monophosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein] Guanosine analog inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein] Quinolones inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein] Sulfonamides inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]

PMID:27592390
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