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Gene: Eif4ebp1 (eukaryotic translation initiation factor 4E binding protein 1) Rattus norvegicus
Symbol: Eif4ebp1
Name: eukaryotic translation initiation factor 4E binding protein 1
Description: Exhibits eukaryotic initiation factor 4E binding activity and protein phosphatase 2A binding activity. Involved in several processes, including negative regulation of translational initiation; response to ethanol; and response to ischemia. Localizes to several cellular components, including the glutamatergic synapse; nucleus; and postsynaptic cytosol. Used to study tuberous sclerosis. Orthologous to human EIF4EBP1 (eukaryotic translation initiation factor 4E binding protein 1); PARTICIPATES IN insulin signaling pathway; mTOR signaling pathway; acute myeloid leukemia pathway; INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4E-BP1; eIF4E-binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; phosphorylated heat- and acid-stable protein regulated by insulin 1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01668,954,860 - 68,968,248 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01668,580,263 - 68,593,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41669,110,522 - 69,123,895 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11669,110,729 - 69,124,101 (-)NCBI
Celera1662,716,014 - 62,729,409 (-)NCBICelera
Cytogenetic Map16q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Eif4ebp1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620259
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.