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Gene: Oxt (oxytocin/neurophysin I prepropeptide) Rattus norvegicus
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Symbol: Oxt
Name: oxytocin/neurophysin I prepropeptide
Description: Exhibits neuropeptide hormone activity and oxytocin receptor binding activity. Involved in several processes, including mating; positive regulation of smooth muscle contraction; and regulation of secretion. Localizes to the extracellular space; secretory granule; and terminal bouton. Used to study gastric ulcer and hypertension. Biomarker of hypertension. Orthologous to human OXT (oxytocin/neurophysin I prepropeptide); PARTICIPATES IN oxytocin signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,4-D.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: OT-NPI; oxcytocin; oxytocin; oxytocin, prepropeptide; oxytocin-neurophysin 1; Oxytocin/neurophysin; oxytocin/neurophysin (Oxt) gene, complete gene, complete cds; oxytocin/neurophysin 1 prepropeptide; Rat oxytocin/neurophysin (Oxt) gene complete gene complete cds
Orthologs:
Homo sapiens (human) : OXT (oxytocin/neurophysin I prepropeptide)  HGNC  Alliance
Mus musculus (house mouse) : Oxt (oxytocin)  MGI  Alliance
Canis lupus familiaris (dog) : OXT (oxytocin/neurophysin I prepropeptide)
Sus scrofa (pig) : OXT (oxytocin/neurophysin I prepropeptide)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03123,106,694 - 123,107,534 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03129,604,822 - 129,605,662 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,194,219 - 118,195,056 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13118,097,303 - 118,100,512 (+)NCBI
Celera3116,593,509 - 116,594,349 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Oxt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3238
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.