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Gene: Oxt (oxytocin/neurophysin I prepropeptide) Rattus norvegicus
Symbol: Oxt
Name: oxytocin/neurophysin I prepropeptide
RGD ID: 3238
Description: Exhibits neuropeptide hormone activity and oxytocin receptor binding activity. Involved in several processes, including mating; positive regulation of smooth muscle contraction; and regulation of secretion. Localizes to extracellular space; secretory granule; and terminal bouton. Used to study gastric ulcer and hypertension. Biomarker of hypertension. Orthologous to human OXT (oxytocin/neurophysin I prepropeptide); PARTICIPATES IN oxytocin signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,4-D.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: OT-NPI; oxcytocin; oxytocin; oxytocin, prepropeptide; oxytocin-neurophysin 1; Oxytocin/neurophysin; oxytocin/neurophysin (Oxt) gene, complete gene, complete cds; oxytocin/neurophysin 1 prepropeptide; Rat oxytocin/neurophysin (Oxt) gene complete gene complete cds
Homo sapiens (human) : OXT (oxytocin/neurophysin I prepropeptide)  HGNC  Alliance
Mus musculus (house mouse) : Oxt (oxytocin)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : OXT (oxytocin/neurophysin I prepropeptide)
Canis lupus familiaris (dog) : OXT (oxytocin/neurophysin I prepropeptide)
Sus scrofa (pig) : OXT (oxytocin/neurophysin I prepropeptide)
Chlorocebus sabaeus (African green monkey) : OXT (oxytocin/neurophysin I prepropeptide)
Heterocephalus glaber (naked mole-rat) : Oxt (oxytocin/neurophysin I prepropeptide)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03123,106,694 - 123,107,534 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,106,694 - 123,107,534 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,604,822 - 129,605,662 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,194,219 - 118,195,056 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13118,097,303 - 118,100,512 (+)NCBI
Celera3116,593,509 - 116,594,349 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Oxt
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3238
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.