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Gene: Gria2 (glutamate ionotropic receptor AMPA type subunit 2) Rattus norvegicus
Symbol: Gria2
Name: glutamate ionotropic receptor AMPA type subunit 2
Description: Exhibits several functions, including PDZ domain binding activity; enzyme binding activity; and transmitter-gated ion channel activity. Predicted to contribute to calcium channel regulator activity. Involved in several processes, including modulation of chemical synaptic transmission; protein tetramerization; and response to lithium ion. Localizes to several cellular components, including dendrite; distal axon; and integral component of plasma membrane. Biomarker of status epilepticus. Orthologous to human GRIA2 (glutamate ionotropic receptor AMPA type subunit 2); PARTICIPATES IN N-cadherin signaling pathway; amyotrophic lateral sclerosis pathway; glutamate signaling pathway; INTERACTS WITH (+)-pilocarpine; (S)-AMPA; 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AMPA-selective glutamate receptor 2; GluA2; gluR-B; GluR-K2; GluR2; glutamate receptor 2; glutamate receptor B; glutamate receptor ionotropic AMPA2 (alpha 2); glutamate receptor, ionotropic, 2; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA2; glutamate receptor, ionotropic, AMPA2 (alpha 2)
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02179,584,302 - 179,704,629 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2179,584,308 - 179,704,629 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02198,991,672 - 199,113,059 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42172,265,155 - 172,385,285 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12172,216,247 - 172,335,391 (-)NCBI
Celera2159,991,989 - 160,110,044 (-)NCBICelera
Cytogenetic Map2q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gria2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61862
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.