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Gene: Pik3r2 (phosphoinositide-3-kinase regulatory subunit 2) Rattus norvegicus
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Symbol: Pik3r2
Name: phosphoinositide-3-kinase regulatory subunit 2
Description: Predicted to have several functions, including 1-phosphatidylinositol-3-kinase regulator activity; enzyme binding activity; and phosphatidylinositol 3-kinase regulatory subunit binding activity. Involved in negative regulation of cell migration involved in sprouting angiogenesis. Predicted to localize to focal adhesion; nucleus; and phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in pancreatic ductal adenocarcinoma. Orthologous to human PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; FasL mediated signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC108697; phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; phosphatidylinositol 3-kinase regulartory subunit polypeptide 2; phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase regulatory subunit polypeptide 2 (p85 beta); phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosphoinositide-3-kinase, regulatory subunit 2 (beta); PI3-kinase p85 subunit beta; PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PI3K regulatory subunit beta; ptdIns-3-kinase p85-beta; ptdIns-3-kinase regulatory subunit beta; ptdIns-3-kinase regulatory subunit p85-beta
Orthologs:
Homo sapiens (human) : PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2)  HGNC  Alliance
Mus musculus (house mouse) : Pik3r2 (phosphoinositide-3-kinase regulatory subunit 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pik3r2 (phosphoinositide-3-kinase regulatory subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2)
Canis lupus familiaris (dog) : PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pik3r2 (phosphoinositide-3-kinase regulatory subunit 2)
Sus scrofa (pig) : PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2)
Chlorocebus sabaeus (African green monkey) : PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2)
Heterocephalus glaber (naked mole-rat) : Pik3r2 (phosphoinositide-3-kinase regulatory subunit 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01620,415,109 - 20,424,982 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,416,432 - 20,424,980 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,273,500 - 20,282,051 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,171,101 - 19,179,650 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11619,171,098 - 19,179,648 (+)NCBI
Celera1618,857,756 - 18,866,282 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pik3r2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68341
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.