Erap1 (endoplasmic reticulum aminopeptidase 1) - Rat Genome Database
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Gene: Erap1 (endoplasmic reticulum aminopeptidase 1) Rattus norvegicus
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Symbol: Erap1
Name: endoplasmic reticulum aminopeptidase 1
RGD ID: 708542
Description: Exhibits aminopeptidase activity; tumor necrosis factor receptor binding activity; and zinc ion binding activity. Involved in proteolysis. Localizes to endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in cervix carcinoma. Orthologous to human ERAP1 (endoplasmic reticulum aminopeptidase 1); INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: A-LAP; adipocyte-derived leucine aminopeptidase; aminopeptidase PILS; Appils; ARTS-1; Arts1; ER-aminopeptidase 1; leucyl-specific aminopeptidase PILS; MGC112613; PILS-AP; puromycin-insensitive leucyl-specific aminopeptidase; type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.223,931,817 - 3,970,735 (+)NCBI
Rnor_6.0 Ensembl21,410,934 - 1,449,733 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.021,410,877 - 1,449,734 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.021,381,061 - 1,419,645 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.421,453,878 - 1,492,671 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.121,457,924 - 1,492,670 (+)NCBI
Celera2431,649 - 466,037 (+)NCBICelera
Cytogenetic Map2q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Additional References at PubMed
PMID:10220586   PMID:11056387   PMID:11964289   PMID:12436110   PMID:12477932   PMID:12748171   PMID:16502470   PMID:17088086   PMID:19199708   PMID:19946888   PMID:23610143  


Genomics

Comparative Map Data
Erap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.223,931,817 - 3,970,735 (+)NCBI
Rnor_6.0 Ensembl21,410,934 - 1,449,733 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.021,410,877 - 1,449,734 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.021,381,061 - 1,419,645 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.421,453,878 - 1,492,671 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.121,457,924 - 1,492,670 (+)NCBI
Celera2431,649 - 466,037 (+)NCBICelera
Cytogenetic Map2q11NCBI
ERAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl596,760,810 - 96,808,100 (-)EnsemblGRCh38hg38GRCh38
GRCh38596,760,273 - 96,935,983 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37596,096,517 - 96,149,848 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36596,122,270 - 96,169,648 (-)NCBINCBI36hg18NCBI36
Build 34596,122,276 - 96,169,398NCBI
Celera591,980,937 - 92,028,293 (-)NCBI
Cytogenetic Map5q15NCBI
HuRef591,286,769 - 91,340,086 (-)NCBIHuRef
CHM1_1595,529,237 - 95,582,553 (-)NCBICHM1_1
Erap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391374,787,692 - 74,841,324 (+)NCBIGRCm39mm39
GRCm39 Ensembl1374,787,687 - 74,841,320 (+)Ensembl
GRCm381374,639,573 - 74,693,205 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1374,639,568 - 74,693,201 (+)EnsemblGRCm38mm10GRCm38
MGSCv371374,777,320 - 74,829,323 (+)NCBIGRCm37mm9NCBIm37
MGSCv361375,105,874 - 75,157,877 (+)NCBImm8
Celera1376,970,386 - 77,021,970 (+)NCBICelera
Cytogenetic Map13C1NCBI
Erap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541815,830,371 - 15,859,720 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541815,827,560 - 15,859,720 (+)NCBIChiLan1.0ChiLan1.0
ERAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1597,625,811 - 97,799,499 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl597,641,353 - 97,668,365 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0592,061,414 - 92,119,087 (-)NCBIMhudiblu_PPA_v0panPan3
ERAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl312,879,477 - 12,919,634 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1312,879,823 - 12,920,710 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Erap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365236,661,119 - 6,686,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2103,378,429 - 103,408,759 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12103,378,428 - 103,415,066 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22107,137,501 - 107,167,876 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERAP1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1490,591,198 - 90,642,331 (-)NCBI
ChlSab1.1 Ensembl490,600,690 - 90,637,563 (-)Ensembl
Erap1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474315,407,217 - 15,442,610 (-)NCBI

Position Markers
UniSTS:495933  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.021,421,869 - 1,421,963NCBIRnor6.0
Rnor_5.021,392,045 - 1,392,139UniSTSRnor5.0
RGSC_v3.421,464,806 - 1,464,900UniSTSRGSC3.4
Celera2438,530 - 438,624UniSTS
Cytogenetic Map2q11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631682Bp115Blood pressure QTL 1154.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135167060Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141179397Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:45
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000013625
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 32 57 41 19 41 8 8 23 34 33 11 8
Low 11 3 51 1 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000013625   ⟹   ENSRNOP00000013625
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl21,410,934 - 1,449,733 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080222   ⟹   ENSRNOP00000072424
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl21,410,941 - 1,449,733 (+)Ensembl
RefSeq Acc Id: NM_030836   ⟹   NP_110463
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.223,931,942 - 3,970,735 (+)NCBI
Rnor_6.021,410,941 - 1,449,734 (+)NCBI
Rnor_5.021,381,061 - 1,419,645 (+)NCBI
RGSC_v3.421,453,878 - 1,492,671 (+)RGD
Celera2431,649 - 466,037 (+)RGD
Sequence:
RefSeq Acc Id: XM_006231700   ⟹   XP_006231762
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.223,931,925 - 3,970,735 (+)NCBI
Rnor_6.021,410,938 - 1,449,734 (+)NCBI
Rnor_5.021,381,061 - 1,419,645 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231701   ⟹   XP_006231763
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.223,931,818 - 3,970,735 (+)NCBI
Rnor_6.021,410,877 - 1,449,734 (+)NCBI
Rnor_5.021,381,061 - 1,419,645 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231704   ⟹   XP_006231766
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.223,931,818 - 3,970,735 (+)NCBI
Rnor_6.021,410,877 - 1,449,734 (+)NCBI
Rnor_5.021,381,061 - 1,419,645 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008760600   ⟹   XP_008758822
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.021,412,828 - 1,449,734 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008760601   ⟹   XP_008758823
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.223,931,817 - 3,970,735 (+)NCBI
Rnor_6.021,412,827 - 1,449,734 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008760602   ⟹   XP_008758824
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.021,412,829 - 1,449,734 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039103202   ⟹   XP_038959130
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.223,931,817 - 3,970,659 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_110463   ⟸   NM_030836
- Peptide Label: precursor
- UniProtKB: Q9JJ22 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006231763   ⟸   XM_006231701
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006231766   ⟸   XM_006231704
- Peptide Label: isoform X3
- UniProtKB: Q4KMA8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231762   ⟸   XM_006231700
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008758823   ⟸   XM_008760601
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008758822   ⟸   XM_008760600
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008758824   ⟸   XM_008760602
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000072424   ⟸   ENSRNOT00000080222
RefSeq Acc Id: ENSRNOP00000013625   ⟸   ENSRNOT00000013625
RefSeq Acc Id: XP_038959130   ⟸   XM_039103202
- Peptide Label: isoform X4
Protein Domains
ERAP1_C   Peptidase_M1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691029
Promoter ID:EPDNEW_R1554
Type:multiple initiation site
Name:Erap1_1
Description:endoplasmic reticulum aminopeptidase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.021,410,914 - 1,410,974EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708542 AgrOrtholog
Ensembl Genes ENSRNOG00000009997 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000013625 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000072424 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013625 UniProtKB/TrEMBL
  ENSRNOT00000080222 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1730 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7192921 IMAGE-MGC_LOAD
InterPro Aminopeptidase_N-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ERAP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ERAP1-like_C_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  M1_APN-typ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:80897 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112613 IMAGE-MGC_LOAD
NCBI Gene 80897 ENTREZGENE
PANTHER PTHR11533:SF156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ERAP1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Erap1 PhenoGen
PRINTS ALADIPTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ZINC_PROTEASE UniProtKB/Swiss-Prot
Superfamily-SCOP SSF63737 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K2Y3_RAT UniProtKB/TrEMBL
  ERAP1_RAT UniProtKB/Swiss-Prot
  Q4KMA8 ENTREZGENE, UniProtKB/TrEMBL
  Q9JJ22 ENTREZGENE
UniProt Secondary Q9JJ23 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-25 Erap1  endoplasmic reticulum aminopeptidase 1  Arts1  type 1 tumor necrosis factor receptor shedding aminopeptidase regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Arts1  type 1 tumor necrosis factor receptor shedding aminopeptidase regulator  Appils  leucyl-specific aminopeptidase PILS  Symbol and Name updated 1299863 APPROVED