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Gene: Fgb (fibrinogen beta chain) Rattus norvegicus
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Symbol: Fgb
Name: fibrinogen beta chain
Description: Predicted to contribute to cell adhesion molecule binding activity and signaling receptor binding activity. Involved in cellular response to interleukin-1 and cellular response to leptin stimulus. Localizes to the blood microparticle and cytoplasm. Biomarker of pancreatitis and pulmonary embolism. Human ortholog(s) of this gene implicated in cardiovascular system disease (multiple); congenital afibrinogenemia; and end stage renal failure. Orthologous to human FGB (fibrinogen beta chain); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ab1-181; Ab1-216; Ac1-581; beta-fibrinogen; Fibrinogen B beta polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; liver regeneration-related protein LRRG036/LRRG043/LRRG189
Orthologs:
Homo sapiens (human) : FGB (fibrinogen beta chain)  HGNC  Alliance
Mus musculus (house mouse) : Fgb (fibrinogen beta chain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgb (fibrinogen beta chain)
Pan paniscus (bonobo/pygmy chimpanzee) : FGB (fibrinogen beta chain)
Canis lupus familiaris (dog) : FGB (fibrinogen beta chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgb (fibrinogen beta chain)
Sus scrofa (pig) : FGB (fibrinogen beta chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02182,028,044 - 182,035,026 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2182,027,115 - 182,038,178 (-)Ensembl
Rnor_5.02201,442,664 - 201,449,657 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42174,768,193 - 174,775,102 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12174,718,265 - 174,725,209 (-)NCBI
Celera2162,422,542 - 162,429,467 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fgb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2604
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.