Gene: Jak3 (Janus kinase 3) Rattus norvegicus
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Symbol: Jak3
Name: Janus kinase 3
Description: ENCODES a protein that exhibits protein phosphatase binding (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway; positive regulation of activated T cell proliferation; positive regulation of calcium ion transport; PARTICIPATES IN altered Jak-Stat signaling pathway; interleukin-2 signaling pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Colonic Neoplasms; Diabetes Mellitus, Experimental ; Experimental Arthritis; FOUND IN cytoplasm; INTERACTS WITH bisphenol A; cadmium dichloride; endosulfan
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: JAK-3; Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; RATJAK3; tyrosine-protein kinase JAK3
Orthologs:
Homo sapiens (human) : JAK3 (Janus kinase 3)  HGNC  Alliance
Mus musculus (house mouse) : Jak3 (Janus kinase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Jak3 (Janus kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : JAK3 (Janus kinase 3)
Canis lupus familiaris (dog) : JAK3 (Janus kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Jak3 (Janus kinase 3)
Sus scrofa (pig) : JAK3 (Janus kinase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01620,107,471 - 20,120,678 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01619,968,486 - 19,981,132 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,878,139 - 18,889,441 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11618,878,136 - 18,889,439 (+)NCBI
Celera1618,589,820 - 18,601,138 (+)NCBICelera
Cytogenetic Map16p14NCBI
RH 3.4 Map16181.8RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Jak3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2940
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE