Abhd6 (abhydrolase domain containing 6, acylglycerol lipase) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Abhd6 (abhydrolase domain containing 6, acylglycerol lipase) Rattus norvegicus
Analyze
Symbol: Abhd6
Name: abhydrolase domain containing 6, acylglycerol lipase
RGD ID: 1359323
Description: Predicted to enable acylglycerol lipase activity and phospholipase activity. Predicted to be involved in several processes, including monoacylglycerol catabolic process; negative regulation of cold-induced thermogenesis; and phospholipid metabolic process. Predicted to act upstream of or within long-term synaptic depression; negative regulation of cell migration; and regulation of endocannabinoid signaling pathway. Predicted to be located in late endosome membrane and lysosomal membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynaptic membrane. Orthologous to human ABHD6 (abhydrolase domain containing 6, acylglycerol lipase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 2-arachidonoylglycerol hydrolase; abhydrolase domain containing 6; abhydrolase domain-containing protein 6; MGC94917; monoacylglycerol lipase ABHD6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21516,859,740 - 16,907,094 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1516,859,738 - 16,906,985 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1519,034,098 - 19,081,627 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01519,992,574 - 20,040,102 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01518,247,481 - 18,295,013 (-)NCBIRnor_WKY
Rnor_6.01518,647,903 - 18,695,133 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1518,647,844 - 18,695,133 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01522,614,361 - 22,661,344 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41518,846,512 - 18,894,003 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11518,846,513 - 18,894,003 (-)NCBI
Celera1516,815,723 - 16,863,221 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-arachidonoylglycerol  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
azoxystrobin  (ISO)
Benoxacor  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
captan  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
Cyclopamine  (ISO)
cyclosporin A  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
finasteride  (EXP)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
oxaliplatin  (EXP)
oxycodone  (EXP)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenylmercury acetate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. null JRS Domain-based curation
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
7. alpha/beta-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes. Zhao S, etal., Cell Rep. 2016 Mar 29;14(12):2872-88. doi: 10.1016/j.celrep.2016.02.076. Epub 2016 Mar 17.
Additional References at PubMed
PMID:15489334   PMID:18096503   PMID:20657592   PMID:22632720   PMID:22969151   PMID:23376485   PMID:24095738   PMID:26491015   PMID:34468198  


Genomics

Comparative Map Data
Abhd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21516,859,740 - 16,907,094 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1516,859,738 - 16,906,985 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1519,034,098 - 19,081,627 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01519,992,574 - 20,040,102 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01518,247,481 - 18,295,013 (-)NCBIRnor_WKY
Rnor_6.01518,647,903 - 18,695,133 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1518,647,844 - 18,695,133 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01522,614,361 - 22,661,344 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41518,846,512 - 18,894,003 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11518,846,513 - 18,894,003 (-)NCBI
Celera1516,815,723 - 16,863,221 (-)NCBICelera
Cytogenetic Map15p14NCBI
ABHD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38358,237,792 - 58,294,734 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl358,237,532 - 58,295,693 (+)EnsemblGRCh38hg38GRCh38
GRCh37358,223,519 - 58,280,461 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36358,198,349 - 58,255,501 (+)NCBINCBI36Build 36hg18NCBI36
Build 34358,198,348 - 58,255,499NCBI
Celera358,237,772 - 58,295,009 (+)NCBICelera
Cytogenetic Map3p14.3NCBI
HuRef358,320,101 - 58,376,917 (+)NCBIHuRef
CHM1_1358,173,601 - 58,230,753 (+)NCBICHM1_1
T2T-CHM13v2.0358,278,191 - 58,335,141 (+)NCBIT2T-CHM13v2.0
Abhd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391414,413,000 - 14,466,885 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1414,413,010 - 14,466,871 (-)EnsemblGRCm39 Ensembl
GRCm38148,002,888 - 8,056,773 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl148,002,902 - 8,056,763 (+)EnsemblGRCm38mm10GRCm38
MGSCv37148,835,416 - 8,889,069 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36146,794,781 - 6,848,434 (+)NCBIMGSCv36mm8
Celera143,626,234 - 3,679,797 (+)NCBICelera
Cytogenetic Map14A1NCBI
Abhd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554301,808,924 - 1,861,441 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554301,809,969 - 1,861,441 (-)NCBIChiLan1.0ChiLan1.0
ABHD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1359,586,537 - 59,641,824 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl359,586,573 - 59,641,824 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0358,172,334 - 58,227,531 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ABHD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12032,301,120 - 32,331,030 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2032,302,104 - 32,330,998 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2032,230,178 - 32,271,085 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02032,573,573 - 32,614,688 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2032,573,597 - 32,614,474 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12032,029,624 - 32,070,713 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02032,386,128 - 32,427,061 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02032,557,760 - 32,599,072 (-)NCBIUU_Cfam_GSD_1.0
Abhd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118169,549,211 - 169,593,878 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364732,687,746 - 2,732,473 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049364732,687,784 - 2,732,413 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABHD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1340,009,737 - 40,060,394 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11339,982,536 - 40,055,467 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21343,989,292 - 44,015,528 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABHD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12219,530,543 - 19,593,083 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2219,542,161 - 19,582,310 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041147,247,753 - 147,302,666 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abhd6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248225,336,427 - 5,376,721 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248225,332,197 - 5,376,372 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Abhd6
276 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:337
Count of miRNA genes:197
Interacting mature miRNAs:233
Transcripts:ENSRNOT00000012271
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)colorectal tumor number (CMO:0001794)15226636822711984Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15226636822711984Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat

Markers in Region
D15Rat138  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21516,887,573 - 16,887,753 (+)MAPPERmRatBN7.2
Rnor_6.01518,675,740 - 18,675,919NCBIRnor6.0
Rnor_5.01522,642,195 - 22,642,374NCBIRnor5.0
RGSC_v3.41518,874,347 - 18,874,526UniSTSRGSC3.4
Celera1516,843,876 - 16,844,055UniSTS
SHRSP x BN Map1515.3399UniSTS
SHRSP x BN Map1515.3399RGD
Cytogenetic Map15p14UniSTS
RH128805  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21516,859,903 - 16,860,091 (+)MAPPERmRatBN7.2
Rnor_6.01518,648,069 - 18,648,256NCBIRnor6.0
Rnor_5.01522,614,527 - 22,614,714UniSTSRnor5.0
RGSC_v3.41518,846,676 - 18,846,863UniSTSRGSC3.4
Celera1516,815,887 - 16,816,074UniSTS
RH 3.4 Map15139.7UniSTS
Cytogenetic Map15p14UniSTS
AV065425  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21516,860,720 - 16,860,812 (+)MAPPERmRatBN7.2
Rnor_6.01518,648,886 - 18,648,977NCBIRnor6.0
Rnor_5.01522,615,344 - 22,615,435UniSTSRnor5.0
RGSC_v3.41518,847,493 - 18,847,584UniSTSRGSC3.4
Celera1516,816,704 - 16,816,795UniSTS
Cytogenetic Map15p14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 2 57 41 19 41 74 35 41 10
Low 41 8 11 1 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000012271   ⟹   ENSRNOP00000012271
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1516,859,738 - 16,906,985 (-)Ensembl
Rnor_6.0 Ensembl1518,647,907 - 18,695,133 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000080794   ⟹   ENSRNOP00000074573
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1516,859,738 - 16,884,547 (-)Ensembl
Rnor_6.0 Ensembl1518,647,844 - 18,675,431 (-)Ensembl
RefSeq Acc Id: NM_001007680   ⟹   NP_001007681
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21516,859,740 - 16,906,970 (-)NCBI
Rnor_6.01518,647,905 - 18,695,133 (-)NCBI
Rnor_5.01522,614,361 - 22,661,344 (-)NCBI
RGSC_v3.41518,846,512 - 18,894,003 (-)RGD
Celera1516,815,723 - 16,863,221 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251767   ⟹   XP_006251829
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21516,859,740 - 16,906,909 (-)NCBI
Rnor_6.01518,647,903 - 18,695,081 (-)NCBI
Rnor_5.01522,614,361 - 22,661,344 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251768   ⟹   XP_006251830
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21516,859,740 - 16,887,826 (-)NCBI
Rnor_6.01518,647,903 - 18,675,973 (-)NCBI
Rnor_5.01522,614,361 - 22,661,344 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093251   ⟹   XP_038949179
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21516,859,740 - 16,907,094 (-)NCBI
RefSeq Acc Id: XM_039093252   ⟹   XP_038949180
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21516,859,740 - 16,874,845 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001007681   ⟸   NM_001007680
- UniProtKB: Q5XI64 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006251829   ⟸   XM_006251767
- Peptide Label: isoform X1
- UniProtKB: Q5XI64 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006251830   ⟸   XM_006251768
- Peptide Label: isoform X1
- UniProtKB: Q5XI64 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074573   ⟸   ENSRNOT00000080794
RefSeq Acc Id: ENSRNOP00000012271   ⟸   ENSRNOT00000012271
RefSeq Acc Id: XP_038949179   ⟸   XM_039093251
- Peptide Label: isoform X1
- UniProtKB: Q5XI64 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038949180   ⟸   XM_039093252
- Peptide Label: isoform X2
Protein Domains
AB hydrolase-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XI64-F1-model_v2 AlphaFold Q5XI64 1-337 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699591
Promoter ID:EPDNEW_R10114
Type:multiple initiation site
Name:Abhd6_1
Description:abhydrolase domain containing 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01518,695,116 - 18,695,176EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359323 AgrOrtholog
BioCyc Gene G2FUF-14285 BioCyc
BioCyc Pathway LIPAS-PWY [triacylglycerol degradation] BioCyc
  PWY-7420 [monoacylglycerol metabolism (yeast)] BioCyc
Ensembl Genes ENSRNOG00000008167 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000012271 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000074573 ENTREZGENE
  ENSRNOP00000074573.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012271 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000080794 ENTREZGENE
  ENSRNOT00000080794.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7112208 IMAGE-MGC_LOAD
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AB_hydrolase_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Epox_hydrolase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:305795 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94917 IMAGE-MGC_LOAD
NCBI Gene 305795 ENTREZGENE
Pfam Abhydrolase_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Abhd6 PhenoGen
PRINTS ABHYDROLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPOXHYDRLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2R9X1_RAT UniProtKB/TrEMBL
  ABHD6_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-13 Abhd6  abhydrolase domain containing 6, acylglycerol lipase  Abhd6  abhydrolase domain containing 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Abhd6  abhydrolase domain containing 6      Symbol and Name status set to approved 1299863 APPROVED
2005-07-29 Abhd6  abhydrolase domain containing 6      Symbol and Name status set to provisional 70820 PROVISIONAL