Plin2 (perilipin 2) - Rat Genome Database

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Gene: Plin2 (perilipin 2) Rattus norvegicus
Analyze
Symbol: Plin2
Name: perilipin 2
RGD ID: 728889
Description: Involved in response to organic cyclic compound and response to xenobiotic stimulus. Located in lipid droplet. Orthologous to human PLIN2 (perilipin 2); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Adfp; adipose differentiation related protein; Adrp; MGC94591; perilipin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25101,156,643 - 101,211,738 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5101,154,411 - 101,242,319 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5103,538,038 - 103,564,407 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05105,328,590 - 105,354,959 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05105,361,730 - 105,388,111 (-)NCBIRnor_WKY
Rnor_6.05104,984,413 - 105,010,863 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5104,984,414 - 105,010,857 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05108,972,976 - 108,999,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45105,718,496 - 105,732,817 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15105,723,721 - 105,738,043 (-)NCBI
Celera599,654,064 - 99,667,851 (-)NCBICelera
Cytogenetic Map5q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
1,4-phenylenediamine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5-triiodo-L-thyronine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (EXP)
acetylsalicylic acid  (EXP)
aconitine  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-linolenic acid  (EXP,ISO)
amphetamine  (EXP)
arachidonic acid  (EXP,ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atorvastatin calcium  (EXP)
atrazine  (ISO)
avobenzone  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (ISO)
benzoates  (ISO)
beta-naphthoflavone  (EXP)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
boron nitride  (ISO)
bromobenzene  (EXP)
buspirone  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
capsaicin  (EXP)
carbon nanotube  (ISO)
celecoxib  (ISO)
chloropicrin  (ISO)
chloroprene  (EXP)
chlorpromazine  (EXP)
ciglitazone  (ISO)
ciprofibrate  (ISO)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (ISO)
Clofop  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (EXP,ISO)
dapagliflozin  (EXP)
deguelin  (ISO)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
diethyl maleate  (ISO)
dioxygen  (EXP,ISO)
diuron  (EXP)
doxorubicin  (ISO)
epoxiconazole  (EXP,ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
farnesol  (ISO)
fenofibrate  (EXP,ISO)
fenpyroximate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fructose  (EXP)
fumonisin B1  (ISO)
gamma-linolenic acid  (ISO)
gemfibrozil  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
glutathione  (ISO)
GW 4064  (ISO)
GW 501516  (ISO)
GW 7647  (ISO)
hexadecanoic acid  (EXP,ISO)
ibuprofen  (EXP,ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
Licarin A  (ISO)
Licochalcone B  (ISO)
lidocaine  (EXP)
metformin  (EXP)
methapyrilene  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (ISO)
Muraglitazar  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
naproxen  (EXP)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nimesulide  (ISO)
nitrofen  (EXP)
ochratoxin A  (ISO)
octadecanoic acid  (ISO)
oleic acid  (EXP,ISO)
oxaliplatin  (EXP)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (ISO)
perflubutane  (ISO)
perfluorobutanesulfonic acid  (ISO)
perfluorobutyric acid  (ISO)
perfluorodecanoic acid  (ISO)
perfluorododecanoic acid  (ISO)
perfluoroheptanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorohexanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perfluoroundecanoic acid  (ISO)
phenformin  (EXP)
phenobarbital  (EXP,ISO)
phorbol 13-acetate 12-myristate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP)
rimonabant  (ISO)
rotenone  (EXP)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
Soman  (EXP)
steviol  (ISO)
stevioside  (ISO)
streptozocin  (EXP)
sumatriptan  (EXP)
sunitinib  (ISO)
Tesaglitazar  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP,ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
topotecan  (EXP)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
troglitazone  (EXP,ISO)
trovafloxacin  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IBA,ISO)
lipid droplet  (IBA,IDA,ISO,TAS)
nucleus  (ISO)
plasma membrane  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Magnolol induces the distributional changes of p160 and adipose differentiation-related protein in adrenal cells. Chien CL, etal., Histochem Cell Biol. 2005 Jun;123(4-5):429-39. Epub 2005 Apr 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide. Imai Y, etal., Gastroenterology. 2007 May;132(5):1947-54. Epub 2007 Feb 23.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Adipose differentiation-related protein has two independent domains for targeting to lipid droplets. Nakamura N and Fujimoto T, Biochem Biophys Res Commun 2003 Jun 27;306(2):333-8.
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Role of adipocyte differentiation-related protein in surfactant phospholipid synthesis by type II cells. Schultz CJ, etal., Am J Physiol Lung Cell Mol Physiol 2002 Aug;283(2):L288-96.
11. Induction of the adipose differentiation-related protein in liver of etomoxir-treated rats. Steiner S, etal., Biochem Biophys Res Commun. 1996 Jan 26;218(3):777-82.
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10358026   PMID:12562852   PMID:14741744   PMID:16448220   PMID:16571721   PMID:16581799   PMID:16627799   PMID:18341646   PMID:19602560   PMID:20198297   PMID:21420243   PMID:24888826  
PMID:25023943   PMID:28336294   PMID:31754142   PMID:33784258  


Genomics

Candidate Gene Status
Plin2 is a candidate Gene for QTL Scl18
Comparative Map Data
Plin2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25101,156,643 - 101,211,738 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5101,154,411 - 101,242,319 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5103,538,038 - 103,564,407 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05105,328,590 - 105,354,959 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05105,361,730 - 105,388,111 (-)NCBIRnor_WKY
Rnor_6.05104,984,413 - 105,010,863 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5104,984,414 - 105,010,857 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05108,972,976 - 108,999,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45105,718,496 - 105,732,817 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15105,723,721 - 105,738,043 (-)NCBI
Celera599,654,064 - 99,667,851 (-)NCBICelera
Cytogenetic Map5q32NCBI
PLIN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38919,108,388 - 19,127,492 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl919,108,375 - 19,149,290 (-)EnsemblGRCh38hg38GRCh38
GRCh37919,115,759 - 19,127,490 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36919,105,759 - 19,117,573 (-)NCBINCBI36Build 36hg18NCBI36
Build 34919,105,759 - 19,117,573NCBI
Celera919,041,952 - 19,053,704 (-)NCBICelera
Cytogenetic Map9p22.1NCBI
HuRef919,077,611 - 19,089,275 (-)NCBIHuRef
CHM1_1919,115,770 - 19,127,537 (-)NCBICHM1_1
T2T-CHM13v2.0919,128,612 - 19,140,276 (-)NCBIT2T-CHM13v2.0
Plin2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39486,545,147 - 86,588,518 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl486,566,623 - 86,588,297 (-)EnsemblGRCm39 Ensembl
GRCm38486,626,910 - 86,670,217 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl486,648,386 - 86,670,060 (-)EnsemblGRCm38mm10GRCm38
MGSCv37486,302,469 - 86,315,963 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36486,127,797 - 86,141,225 (-)NCBIMGSCv36mm8
Celera485,171,641 - 85,185,400 (-)NCBICelera
Cytogenetic Map4C4NCBI
cM Map440.69NCBI
Plin2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543421,574,292 - 21,580,988 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543421,573,860 - 21,580,990 (-)NCBIChiLan1.0ChiLan1.0
PLIN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1919,421,928 - 19,537,676 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl919,421,928 - 19,462,222 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0918,928,455 - 18,951,132 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PLIN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11138,940,063 - 38,959,126 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1138,940,065 - 38,959,070 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1137,598,800 - 37,617,859 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01139,873,157 - 39,892,049 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1139,873,157 - 39,891,976 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11138,566,314 - 38,585,390 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01138,361,251 - 38,380,316 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01138,998,438 - 39,017,321 (-)NCBIUU_Cfam_GSD_1.0
Plin2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947153,369,919 - 153,390,479 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366521,039,248 - 1,059,983 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLIN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1203,683,862 - 203,709,273 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11203,683,867 - 203,709,277 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21227,334,036 - 227,357,123 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103219401
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11260,526,394 - 60,606,262 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1260,590,222 - 60,610,727 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236665992,224 - 20,825 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plin2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473623,111,265 - 23,122,193 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473623,114,149 - 23,122,634 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
15.MMHAP53FRE9.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,174,343 - 101,174,552 (+)MAPPERmRatBN7.2
Rnor_6.05105,002,108 - 105,002,316NCBIRnor6.0
Rnor_5.05108,990,469 - 108,990,677UniSTSRnor5.0
RGSC_v3.45105,724,138 - 105,724,346UniSTSRGSC3.4
Celera599,659,180 - 99,659,388UniSTS
Cytogenetic Map5q32UniSTS
RH140053  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,169,322 - 101,169,541 (+)MAPPERmRatBN7.2
Rnor_6.05104,997,087 - 104,997,305NCBIRnor6.0
Rnor_5.05108,985,651 - 108,985,869UniSTSRnor5.0
RGSC_v3.45105,718,584 - 105,718,802UniSTSRGSC3.4
Celera599,654,153 - 99,654,371UniSTS
RH 3.4 Map5735.3UniSTS
Cytogenetic Map5q32UniSTS
RH140452  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,169,318 - 101,169,483 (+)MAPPERmRatBN7.2
Rnor_6.05104,997,083 - 104,997,247NCBIRnor6.0
Rnor_5.05108,985,647 - 108,985,811UniSTSRnor5.0
RGSC_v3.45105,718,580 - 105,718,744UniSTSRGSC3.4
Celera599,654,149 - 99,654,313UniSTS
Cytogenetic Map5q32UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)568984307104251008Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)599016066119085810Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)599485997103690167Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)599753548113061097Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:300
Count of miRNA genes:188
Interacting mature miRNAs:220
Transcripts:ENSRNOT00000009749
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 58 35 41 11 8
Low 16
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001007144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001400551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001400552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001400553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001400554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001400555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001400556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC108974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW913874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000009749   ⟹   ENSRNOP00000009749
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5101,156,712 - 101,183,025 (-)Ensembl
Rnor_6.0 Ensembl5104,984,414 - 105,010,857 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097668   ⟹   ENSRNOP00000093118
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5101,169,241 - 101,242,319 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105644   ⟹   ENSRNOP00000093929
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5101,169,236 - 101,183,150 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115133   ⟹   ENSRNOP00000079287
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5101,154,411 - 101,183,041 (-)Ensembl
RefSeq Acc Id: NM_001007144   ⟹   NP_001007145
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,169,235 - 101,183,036 (-)NCBI
Rnor_6.05104,996,999 - 105,010,799 (-)NCBI
Rnor_5.05108,972,976 - 108,999,210 (-)NCBI
RGSC_v3.45105,718,496 - 105,732,817 (-)RGD
Celera599,654,064 - 99,667,851 (-)RGD
Sequence:
RefSeq Acc Id: XM_006238360   ⟹   XP_006238422
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,156,643 - 101,183,126 (-)NCBI
Rnor_6.05104,984,413 - 105,010,835 (-)NCBI
Rnor_5.05108,972,976 - 108,999,210 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008763778   ⟹   XP_008762000
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,169,226 - 101,183,129 (-)NCBI
Rnor_6.05104,996,990 - 105,010,835 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109518   ⟹   XP_038965446
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,169,226 - 101,211,738 (-)NCBI
RefSeq Acc Id: XM_039109519   ⟹   XP_038965447
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,156,648 - 101,211,738 (-)NCBI
RefSeq Acc Id: XM_039109520   ⟹   XP_038965448
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,169,226 - 101,211,738 (-)NCBI
RefSeq Acc Id: XM_039109521   ⟹   XP_038965449
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,169,226 - 101,182,927 (-)NCBI
RefSeq Acc Id: XM_039109522   ⟹   XP_038965450
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,169,226 - 101,182,867 (-)NCBI
RefSeq Acc Id: XM_039109524   ⟹   XP_038965452
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,156,648 - 101,182,865 (-)NCBI
RefSeq Acc Id: XM_039109525   ⟹   XP_038965453
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,156,648 - 101,183,129 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001007145   ⟸   NM_001007144
- UniProtKB: Q5U2U5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238422   ⟸   XM_006238360
- Peptide Label: isoform X2
- UniProtKB: F6QBA3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762000   ⟸   XM_008763778
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000009749   ⟸   ENSRNOT00000009749
RefSeq Acc Id: XP_038965447   ⟸   XM_039109519
- Peptide Label: isoform X2
- UniProtKB: F6QBA3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965453   ⟸   XM_039109525
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038965452   ⟸   XM_039109524
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038965448   ⟸   XM_039109520
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038965446   ⟸   XM_039109518
- Peptide Label: isoform X1
- UniProtKB: Q5U2U5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965449   ⟸   XM_039109521
- Peptide Label: isoform X1
- UniProtKB: Q5U2U5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965450   ⟸   XM_039109522
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000079287   ⟸   ENSRNOT00000115133
RefSeq Acc Id: ENSRNOP00000093118   ⟸   ENSRNOT00000097668
RefSeq Acc Id: ENSRNOP00000093929   ⟸   ENSRNOT00000105644

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F6QBA3-F1-model_v2 AlphaFold F6QBA3 1-421 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693825
Promoter ID:EPDNEW_R4350
Type:multiple initiation site
Name:Plin2_1
Description:perilipin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05105,010,797 - 105,010,857EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:728889 AgrOrtholog
BioCyc Gene G2FUF-40842 BioCyc
Ensembl Genes ENSRNOG00000007060 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000009749.5 UniProtKB/TrEMBL
  ENSRNOP00000079287 ENTREZGENE
  ENSRNOP00000079287.1 UniProtKB/TrEMBL
  ENSRNOP00000093118 ENTREZGENE
  ENSRNOP00000093118.1 UniProtKB/TrEMBL
  ENSRNOP00000093929.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009749.6 UniProtKB/TrEMBL
  ENSRNOT00000097668 ENTREZGENE
  ENSRNOT00000097668.1 UniProtKB/TrEMBL
  ENSRNOT00000105644.1 UniProtKB/TrEMBL
  ENSRNOT00000115133 ENTREZGENE
  ENSRNOT00000115133.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7190361 IMAGE-MGC_LOAD
InterPro Perilipin UniProtKB/TrEMBL
KEGG Report rno:298199 UniProtKB/TrEMBL
MGC_CLONE MGC:94591 IMAGE-MGC_LOAD
NCBI Gene 298199 ENTREZGENE
Pfam Perilipin UniProtKB/TrEMBL
PhenoGen Plin2 PhenoGen
PIRSF PAT UniProtKB/TrEMBL
UniProt A0A8I5ZQJ5_RAT UniProtKB/TrEMBL
  A0A8I6AJS7_RAT UniProtKB/TrEMBL
  F6QBA3 ENTREZGENE, UniProtKB/TrEMBL
  Q5U2U5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-28 Plin2  perilipin 2  Adfp  adipose differentiation related protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-04-05 Adfp  adipose differentiation related protein  ADRP  adipose differentiation-related protein  Data Merged 737654 APPROVED
2005-07-29 ADRP  adipose differentiation-related protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-12-14 Adfp  adipose differentiation related protein      Symbol and Name status set to approved 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization in the lung, mRNA expression is concentrated in lipofibroblasts and minimal in fetal alveolar type II epithelial (EPII) cells  
gene_expression mRNA highly expressed in lung; also expressed in heart, brain, spleen, liver, skeletal muscle, kidney, and testes 625646
gene_expression in the lung, mRNA expression is concentrated in lipofibroblasts and minimal in fetal alveolar type II epithelial (EPII) cells 625646
gene_process mediates lipid transfer between lipofibrobalst and alveolar type II epithelial (EPII) cells  
gene_product intrinsic lipid storage droplet protein 625646