PLIN2 (perilipin 2) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PLIN2 (perilipin 2) Sus scrofa
Analyze
Symbol: PLIN2
Name: perilipin 2
RGD ID: 13984625
Description: INVOLVED IN lipid storage (ortholog); long-chain fatty acid transport (ortholog); response to drug (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); fatty liver disease (ortholog); Hypertriglyceridemia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); lipid droplet (ortholog); INTERACTS WITH malathion; melatonin
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ADFP; adipophilin; adipose differentiation-related protein; ADRP; perilipin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1203,683,862 - 203,709,274 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11203,683,867 - 203,709,277 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21227,334,036 - 227,357,123 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
malathion  (EXP)
melatonin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
cytosol  (IBA,IEA,ISO)
lipid droplet  (IBA,IEA,ISO)
membrane  (IEA)
nucleus  (IEA,ISO)
plasma membrane  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:14970690   PMID:16060490   PMID:16167998   PMID:20842447   PMID:21420243   PMID:25131988   PMID:25824029  


Genomics

Comparative Map Data
PLIN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1203,683,862 - 203,709,274 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11203,683,867 - 203,709,277 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21227,334,036 - 227,357,123 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLIN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl919,108,375 - 19,149,290 (-)EnsemblGRCh38hg38GRCh38
GRCh38919,108,391 - 19,127,518 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37919,115,759 - 19,127,490 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36919,105,759 - 19,117,573 (-)NCBINCBI36hg18NCBI36
Build 34919,105,759 - 19,117,573NCBI
Celera919,041,952 - 19,053,704 (-)NCBI
Cytogenetic Map9p22.1NCBI
HuRef919,077,611 - 19,089,275 (-)NCBIHuRef
CHM1_1919,115,770 - 19,127,537 (-)NCBICHM1_1
Plin2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39486,545,147 - 86,588,518 (-)NCBIGRCm39mm39
GRCm39 Ensembl486,566,623 - 86,588,297 (-)Ensembl
GRCm38486,626,910 - 86,670,217 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl486,648,386 - 86,670,060 (-)EnsemblGRCm38mm10GRCm38
MGSCv37486,302,469 - 86,315,963 (-)NCBIGRCm37mm9NCBIm37
MGSCv36486,127,797 - 86,141,225 (-)NCBImm8
Celera485,171,641 - 85,185,400 (-)NCBICelera
Cytogenetic Map4C4NCBI
cM Map440.69NCBI
Plin2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25101,156,643 - 101,211,738 (-)NCBI
Rnor_6.0 Ensembl5104,984,414 - 105,010,857 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05104,984,413 - 105,010,863 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05108,972,976 - 108,999,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45105,718,496 - 105,732,817 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15105,723,721 - 105,738,043 (-)NCBI
Celera599,654,064 - 99,667,851 (-)NCBICelera
Cytogenetic Map5q32NCBI
Plin2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543421,574,292 - 21,580,988 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543421,573,860 - 21,580,990 (-)NCBIChiLan1.0ChiLan1.0
PLIN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1919,421,928 - 19,537,676 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl919,421,928 - 19,462,222 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0918,928,455 - 18,951,132 (-)NCBIMhudiblu_PPA_v0panPan3
PLIN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1138,940,065 - 38,959,070 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11138,940,063 - 38,959,126 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Plin2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366521,039,248 - 1,059,983 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103219401
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11260,526,394 - 60,606,262 (+)NCBI
ChlSab1.1 Ensembl1260,590,222 - 60,610,727 (+)Ensembl
Plin2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473623,114,149 - 23,122,634 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 2 2 1 1 2
Low 8 4 3 3 23 1 2 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_214200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005660074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005660075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013993524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021082975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB527057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEMK02000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF234676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK232656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY550037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY621062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY835336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU481860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU571191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ066658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ066659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01097072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU461314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU461315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU461316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU461317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN616387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC733245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000054843   ⟹   ENSSSCP00000041181
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1203,683,862 - 203,709,274 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000070153   ⟹   ENSSSCP00000073029
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1203,684,047 - 203,697,099 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000079064   ⟹   ENSSSCP00000067740
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1203,683,862 - 203,694,211 (+)Ensembl
RefSeq Acc Id: NM_214200   ⟹   NP_999365
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11203,684,047 - 203,694,674 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005660074   ⟹   XP_005660131
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11203,684,006 - 203,694,677 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005660075   ⟹   XP_005660132
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11203,683,867 - 203,709,277 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013993524   ⟹   XP_013848978
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11203,683,956 - 203,699,149 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021082975   ⟹   XP_020938634
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11203,684,007 - 203,709,277 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005660132   ⟸   XM_005660075
- Peptide Label: isoform X2
- UniProtKB: A0A287AAY1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013848978   ⟸   XM_013993524
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005660131   ⟸   XM_005660074
- Peptide Label: isoform X1
- UniProtKB: D0G0B6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020938634   ⟸   XM_021082975
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_999365   ⟸   NM_214200
- UniProtKB: Q9MZE5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000041181   ⟸   ENSSSCT00000054843
RefSeq Acc Id: ENSSSCP00000073029   ⟸   ENSSSCT00000070153
RefSeq Acc Id: ENSSSCP00000067740   ⟸   ENSSSCT00000079064


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000035863 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070030233 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000041181 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000067740 UniProtKB/TrEMBL
  ENSSSCP00000073029 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070051842 UniProtKB/TrEMBL
  ENSSSCP00070051843 UniProtKB/TrEMBL
  ENSSSCP00070051845 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000054843 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000070153 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000079064 UniProtKB/TrEMBL
  ENSSSCT00070060834 UniProtKB/TrEMBL
  ENSSSCT00070060835 UniProtKB/TrEMBL
  ENSSSCT00070060837 UniProtKB/TrEMBL
InterPro Perilipin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397402 UniProtKB/TrEMBL
NCBI Gene PLIN2 ENTREZGENE
Pfam Perilipin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF PAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287AAY1 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1WBF2_PIG UniProtKB/TrEMBL
  A0A4X1WBQ4_PIG UniProtKB/TrEMBL
  A0A4X1WCX4_PIG UniProtKB/TrEMBL
  A0A5G2QS35_PIG UniProtKB/TrEMBL
  D0G0B6 ENTREZGENE, UniProtKB/TrEMBL
  E2E6Q9_PIG UniProtKB/TrEMBL
  E2E6R0_PIG UniProtKB/TrEMBL
  E2E6R1_PIG UniProtKB/TrEMBL
  PLIN2_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q9MZE5 ENTREZGENE, UniProtKB/TrEMBL
  R9WDQ0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:91558 ENTREZGENE