(+)-epicatechin-3-O-gallate multiple interactions ISO RGD:1348034 6480464 [Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] affects the reaction [Hydrogen Peroxide affects the expression of CLOCK mRNA], [Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] affects the reaction [Hydrogen Peroxide affects the expression of CLOCK protein] CTD PMID:29061316 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1348034 6480464 [Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] affects the reaction [Hydrogen Peroxide affects the expression of CLOCK mRNA] more ... CTD PMID:22079256 , PMID:29061316 1,2-dimethylhydrazine decreases expression ISO RGD:1552430 6480464 1, 2-Dimethylhydrazine results in decreased expression of CLOCK mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:1552430 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLOCK mRNA CTD PMID:22206623 17alpha-ethynylestradiol affects expression ISO RGD:1552430 6480464 Ethinyl Estradiol affects the expression of CLOCK mRNA CTD PMID:17555576 17alpha-ethynylestradiol increases expression ISO RGD:1552430 6480464 Ethinyl Estradiol results in increased expression of CLOCK mRNA CTD PMID:17942748 17alpha-ethynylestradiol multiple interactions ISO RGD:1552430 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CLOCK mRNA CTD PMID:17942748 2,2',4,4',5,5'-hexachlorobiphenyl increases activity ISO RGD:1348034 6480464 2 more ... CTD PMID:27589886 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1552430 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 2,2',5,5'-tetrachlorobiphenyl increases expression ISO RGD:1348034 6480464 2 more ... CTD PMID:21703328 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1552430 6480464 Tetrachlorodibenzodioxin results in increased expression of CLOCK mRNA CTD PMID:17942748 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1552430 6480464 Tetrachlorodibenzodioxin results in decreased expression of CLOCK mRNA CTD PMID:18295293 , PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1552430 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17942748 , PMID:28433925 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1552430 6480464 Tetrachlorodibenzodioxin affects the expression of CLOCK mRNA CTD PMID:21570461 , PMID:28922406 2-amino-2-deoxy-D-glucopyranose decreases expression ISO RGD:1552430 6480464 Glucosamine results in decreased expression of CLOCK mRNA, Glucosamine results in decreased expression of CLOCK protein CTD PMID:24442997 20-HETE affects abundance ISO RGD:1552430 6480464 CLOCK protein affects the abundance of 20-hydroxy-5 more ... CTD PMID:22440902 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:1552430 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of CLOCK mRNA CTD PMID:26251327 4,4'-diaminodiphenylmethane increases expression ISO RGD:1552430 6480464 4, 4'-diaminodiphenylmethane results in increased expression of CLOCK mRNA CTD PMID:18648102 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of CLOCK mRNA CTD PMID:30723492 4,4'-sulfonyldiphenol increases expression ISO RGD:1552430 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of CLOCK mRNA CTD PMID:33297965 acrolein multiple interactions ISO RGD:1348034 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of CLOCK mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of CLOCK mRNA CTD PMID:32699268 aflatoxin B1 increases expression ISO RGD:1552430 6480464 Aflatoxin B1 results in increased expression of CLOCK mRNA CTD PMID:19770486 aldehydo-D-glucosamine decreases expression ISO RGD:1552430 6480464 Glucosamine results in decreased expression of CLOCK mRNA, Glucosamine results in decreased expression of CLOCK protein CTD PMID:24442997 all-trans-retinoic acid multiple interactions ISO RGD:1552430 6480464 RARA protein inhibits the reaction [Tretinoin results in increased activity of [CLOCK protein binds to ARNTL protein]], Tretinoin results in increased activity of [CLOCK protein binds to ARNTL protein] CTD PMID:17069763 alpha-pinene multiple interactions ISO RGD:1348034 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of CLOCK mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of CLOCK mRNA CTD PMID:32699268 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CLOCK mRNA CTD PMID:16483693 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of CLOCK mRNA CTD PMID:30779732 aristolochic acid decreases expression ISO RGD:1348034 6480464 aristolochic acid I results in decreased expression of CLOCK mRNA CTD PMID:33212167 Aroclor 1254 decreases expression ISO RGD:1552430 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CLOCK mRNA CTD PMID:23650126 benzo[a]pyrene increases expression ISO RGD:1348034 6480464 Benzo(a)pyrene results in increased expression of CLOCK mRNA CTD PMID:17879257 benzo[a]pyrene increases expression ISO RGD:1552430 6480464 Benzo(a)pyrene results in increased expression of CLOCK mRNA CTD PMID:20127859 , PMID:22228805 benzo[a]pyrene multiple interactions ISO RGD:1552430 6480464 CLOCK gene mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] CTD PMID:21978865 benzo[b]fluoranthene decreases expression ISO RGD:1552430 6480464 benzo(b)fluoranthene results in decreased expression of CLOCK mRNA CTD PMID:26377693 beta-D-glucosamine decreases expression ISO RGD:1552430 6480464 Glucosamine results in decreased expression of CLOCK mRNA, Glucosamine results in decreased expression of CLOCK protein CTD PMID:24442997 beta-naphthoflavone multiple interactions ISO RGD:1552430 6480464 beta-Naphthoflavone inhibits the reaction [CLOCK protein binds to ARNTL protein], beta-Naphthoflavone inhibits the reaction [CLOCK protein binds to PER1 promoter] CTD PMID:20106950 bezafibrate multiple interactions ISO RGD:1552430 6480464 [CLOCK protein binds to ARNTL protein] promotes the reaction [Bezafibrate results in increased expression of SERPINE1 mRNA], CLOCK protein affects the reaction [Bezafibrate results in increased expression of SERPINE1 mRNA] CTD PMID:20400680 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of CLOCK mRNA CTD PMID:28871463 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:1552430 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CLOCK mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:1552430 6480464 bisphenol A results in increased expression of CLOCK mRNA CTD PMID:33221593 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CLOCK mRNA CTD PMID:30816183 bisphenol A affects methylation ISO RGD:1552430 6480464 bisphenol A affects the methylation of CLOCK promoter CTD PMID:27334623 bisphenol A multiple interactions ISO RGD:1552430 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of CLOCK gene CTD PMID:28505145 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of CLOCK mRNA CTD PMID:32479839 butanal decreases expression ISO RGD:1348034 6480464 butyraldehyde results in decreased expression of CLOCK mRNA CTD PMID:26079696 cadmium dichloride affects expression EXP 6480464 Cadmium Chloride affects the expression of CLOCK, Cadmium Chloride affects the expression of CLOCK mRNA CTD PMID:21442002 , PMID:23085516 cadmium dichloride multiple interactions EXP 6480464 Melatonin inhibits the reaction [Cadmium Chloride affects the expression of CLOCK] CTD PMID:23085516 cadmium dichloride affects methylation EXP 6480464 Cadmium Chloride affects the methylation of CLOCK promoter CTD PMID:22457795 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of CLOCK mRNA CTD PMID:20107868 cannabidiol decreases expression ISO RGD:1552430 6480464 Cannabidiol results in decreased expression of CLOCK mRNA CTD PMID:30307084 , PMID:33019509 cannabigerol decreases expression ISO RGD:1552430 6480464 cannabigerol results in decreased expression of CLOCK mRNA CTD PMID:33019509 carbon nanotube increases expression ISO RGD:1552430 6480464 Nanotubes, Carbon results in increased expression of CLOCK mRNA CTD PMID:25554681 , PMID:25620056 CGS-21680 increases expression ISO RGD:1348034 6480464 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of CLOCK mRNA CTD PMID:22923002 cisplatin decreases expression ISO RGD:1348034 6480464 Cisplatin results in decreased expression of CLOCK protein CTD PMID:21157427 clozapine affects response to substance ISO RGD:1348034 6480464 CLOCK gene SNP affects the susceptibility to Clozapine CTD PMID:15331141 cocaine increases expression ISO RGD:1552430 6480464 Cocaine results in increased expression of CLOCK mRNA CTD PMID:15994025 crocidolite asbestos decreases expression ISO RGD:1348034 6480464 Asbestos, Crocidolite results in decreased expression of CLOCK mRNA CTD PMID:29523930 DDE increases activity ISO RGD:1348034 6480464 Dichlorodiphenyl Dichloroethylene results in increased activity of CLOCK protein CTD PMID:27589886 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of CLOCK mRNA CTD PMID:23640034 dexamethasone affects expression ISO RGD:1348034 6480464 Dexamethasone affects the expression of CLOCK mRNA CTD PMID:23251369 dibenz[a,h]anthracene decreases expression ISO RGD:1552430 6480464 1 more ... CTD PMID:26377693 dichloromethane decreases expression ISO RGD:1552430 6480464 Methylene Chloride results in decreased expression of CLOCK mRNA CTD PMID:28392392 doxorubicin decreases expression ISO RGD:1348034 6480464 Doxorubicin results in decreased expression of CLOCK mRNA CTD PMID:29803840 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of CLOCK mRNA CTD PMID:29391264 fluoxetine increases expression ISO RGD:1552430 6480464 Fluoxetine results in increased expression of CLOCK mRNA CTD PMID:15994025 folic acid multiple interactions ISO RGD:1552430 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CLOCK mRNA CTD PMID:22206623 furan increases expression ISO RGD:1552430 6480464 furan results in increased expression of CLOCK mRNA CTD PMID:24183702 gallic acid multiple interactions ISO RGD:1348034 6480464 [Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] affects the reaction [Hydrogen Peroxide affects the expression of CLOCK mRNA], [Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] affects the reaction [Hydrogen Peroxide affects the expression of CLOCK protein] CTD PMID:29061316 gallocatechin multiple interactions ISO RGD:1348034 6480464 [Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] affects the reaction [Hydrogen Peroxide affects the expression of CLOCK mRNA], [Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] affects the reaction [Hydrogen Peroxide affects the expression of CLOCK protein] CTD PMID:29061316 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of CLOCK mRNA CTD PMID:33387578 hexadecanoic acid decreases expression ISO RGD:1552430 6480464 Palmitic Acid results in decreased expression of CLOCK mRNA, Palmitic Acid results in decreased expression of CLOCK protein CTD PMID:24442997 hydrogen peroxide multiple interactions ISO RGD:1348034 6480464 [Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] affects the reaction [Hydrogen Peroxide affects the expression of CLOCK mRNA] more ... CTD PMID:29061316 , PMID:30316844 hydrogen peroxide affects expression ISO RGD:1348034 6480464 Hydrogen Peroxide affects the expression of CLOCK mRNA, Hydrogen Peroxide affects the expression of CLOCK protein CTD PMID:29061316 , PMID:30316844 lead(0) decreases expression ISO RGD:1348034 6480464 Lead results in decreased expression of CLOCK mRNA CTD PMID:19921347 lead(2+) decreases expression ISO RGD:1348034 6480464 Lead results in decreased expression of CLOCK mRNA CTD PMID:19921347 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of CLOCK mRNA CTD PMID:28511934 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Cadmium Chloride affects the expression of CLOCK] CTD PMID:23085516 methidathion decreases expression ISO RGD:1552430 6480464 methidathion results in decreased expression of CLOCK mRNA CTD PMID:34813904 methylmercury chloride decreases expression ISO RGD:1348034 6480464 methylmercuric chloride results in decreased expression of CLOCK mRNA CTD PMID:28001369 N-nitrosodiethylamine multiple interactions ISO RGD:1552430 6480464 CLOCK protein promotes the reaction [Diethylnitrosamine results in increased activity of CASP3 protein] more ... CTD PMID:17942915 , PMID:21167249 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLOCK mRNA CTD PMID:20360939 N-nitrosodiethylamine increases response to substance ISO RGD:1552430 6480464 CLOCK protein results in increased susceptibility to Diethylnitrosamine CTD PMID:21167249 N-nitrosodiethylamine increases expression ISO RGD:1552430 6480464 Diethylnitrosamine results in increased expression of CLOCK mRNA CTD PMID:17942915 ozone multiple interactions ISO RGD:1348034 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of CLOCK mRNA more ... CTD PMID:32699268 parathion decreases expression ISO RGD:1552430 6480464 Parathion results in decreased expression of CLOCK mRNA CTD PMID:34813904 pentanal decreases expression ISO RGD:1348034 6480464 pentanal results in decreased expression of CLOCK mRNA CTD PMID:26079696 perfluorooctanoic acid increases expression ISO RGD:1348034 6480464 perfluorooctanoic acid results in increased expression of CLOCK mRNA CTD PMID:23146750 phenethyl caffeate multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLOCK mRNA CTD PMID:20360939 phenobarbital decreases expression ISO RGD:1552430 6480464 Phenobarbital results in decreased expression of CLOCK mRNA CTD PMID:19270015 pirinixic acid increases expression ISO RGD:1552430 6480464 pirinixic acid results in increased expression of CLOCK mRNA CTD PMID:23811191 pirinixic acid multiple interactions ISO RGD:1552430 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CLOCK mRNA CTD PMID:19710929 potassium chromate decreases expression ISO RGD:1348034 6480464 potassium chromate(VI) results in decreased expression of CLOCK mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:1348034 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CLOCK mRNA CTD PMID:22079256 rotenone multiple interactions EXP 6480464 [lipopolysaccharide more ... CTD PMID:30328585 sodium arsenate increases expression ISO RGD:1552430 6480464 sodium arsenate results in increased expression of CLOCK mRNA CTD PMID:21795629 sodium arsenite decreases expression ISO RGD:1552430 6480464 sodium arsenite results in decreased expression of CLOCK mRNA CTD PMID:30130555 styrene decreases expression ISO RGD:1552430 6480464 Styrene results in decreased expression of CLOCK mRNA CTD PMID:28951217 sunitinib increases expression ISO RGD:1348034 6480464 Sunitinib results in increased expression of CLOCK mRNA CTD PMID:31533062 tamoxifen affects expression ISO RGD:1552430 6480464 Tamoxifen affects the expression of CLOCK mRNA CTD PMID:17555576 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of CLOCK mRNA CTD PMID:31150632 tetraphene decreases expression ISO RGD:1552430 6480464 benz(a)anthracene results in decreased expression of CLOCK mRNA CTD PMID:26377693 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of CLOCK mRNA CTD PMID:34492290 trichloroethene decreases methylation EXP 6480464 Trichloroethylene results in decreased methylation of CLOCK gene CTD PMID:27618143 triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of CLOCK mRNA CTD PMID:30589522 valproic acid decreases expression ISO RGD:1348034 6480464 Valproic Acid results in decreased expression of CLOCK mRNA CTD PMID:23179753 , PMID:28001369 valproic acid decreases methylation ISO RGD:1348034 6480464 Valproic Acid results in decreased methylation of CLOCK gene CTD PMID:29154799 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of CLOCK mRNA CTD PMID:23034163
